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EMBL
Euro-BioImaging Bio-Hub - Administrator
Heidelberg, Germany
Europe
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Deadline: Apr 25, 2024

The international Euro-BioImaging Bio-Hub team hosted by EMBL in Heidelberg, Germany, is seeking a dynamic individual with a background in administration and finance, ideally with previous experience in supporting international travel administration. This pivotal role involves supporting the Bio-Hub team in administering the finances of their growing portfolio of EU-funded projects as well as in supporting the organisation of external activities such as webinars, smaller in person events or training courses.

EMBL
Global BioImaging Network Manager
Heidelberg, Germany
Europe
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Deadline: Apr 25, 2024

The international Global BioImaging team, operating within the Euro-BioImaging Bio-Hub hosted by EMBL in Heidelberg, Germany, is seeking a dynamic individual with a scientific management and, ideally, imaging background. This pivotal role involves supporting and coordinating our network of Global BioImaging partners (www.globalbioimaging.org), contributing to strategic initiatives, supporting our communication activities and ensuring seamless execution of administrative functions linked to the GBI activities. If you're passionate about advancing bioimaging research on a global scale and thrive in a collaborative environment, we invite you to apply and be part of our impactful mission (www.globalbioimaging.org).

Max Planck Institute for Biological Intelligence (MPI-BI)
Microscopy Specialist
Munich, Bavaria, Germany
Europe
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Deadline: Apr 22, 2024

The Max Planck Institute for Biological Intelligence (MPI-BI) is located in the southwest of Munich, with its two locations in Martinsried and Seewiesen. It is one of more than 80 independent research institutes of the Max Planck Society. With around 500 employees from more than 50 nations, we investigate the fundamentals of "biological intelligence". We aim to understand how, in the course of evolution, animals developed abilities to cope with a constantly changing environment and to find ever new solutions to problems.

Within other service units, the Imaging Facility supports scientists in many aspects of modern microscopy. Our aim is to maintain our state-of-the-art instruments, train scientists on various light setups, support them in establishing their experimental pipelines and develop new techniques or microscopes to tackle new challenges in modern neuroscience. We are looking for a: Microscopy Specialist (m/f/d).

Your responsibilities

  • First level maintenance and troubleshooting of a variety of instruments including widefield,  confocal, spinning disk, 2-photon and lightsheet microscopes.
  • Theoretical and practical training of institute members.
  • Selection, installation and upgrade of commercial systems.
  • Development of new optical hardware and applications as well as solutions for image processing and analysis.

    Your profile

  • Diploma or Master’s degree in biophysics, physics or biology with a strong focus on microscopy, PhD is an advantage.
  • Excellent knowledge of principles and methods of microscopy (including fluorescence, confocal and 2-photon microscopy, properties of light sources and detectors).
  • Good skills in handling optics, microscopy hardware and software.
  • High degree of motivation and self-reliance combined with excellent organizational and team-work skills.
  • A strong sense for diligence and accuracy.
  • Fluent in English, German is an advantage.

    What we offer

  • An interesting, multifaceted and rewarding job in a scientific, modern and international environment.
  • Opportunities for regular professional exchange, individual training and further qualification.
  • Remuneration according to TVöD Bund, depending on qualifications, activities and experience.
  • Social benefits of the public service (company pension scheme (VBL), annual bonus, subsidized MVV job ticket, group accident insurance).
  • Modern workplaces and active company health management with health and sports facilities.
  • Work-life balance (cooperation with a family service, flexible working hours).
  • A diverse working environment where equal opportunities and diversity are actively promoted.

The position is initially limited to a period of 2 years, with the possibility of an extension or a permanent contract depending on the suitable candidate. The Max Planck Society strives for gender equality and diversity. Furthermore, the Max Planck Society wants to increase the proportion of women in areas in which they are underrepresented. Women are therefore expressly encouraged to apply. The Max Planck Society has set itself the goal of employing more disabled people who are thus explicitely encouraged to apply. If you have any questions, please contact Claudio Polisseni via claudio.polisseni@bi.mpg.de.

Your application

Did we attract your interest? Then please apply until 22.04.2024 by submitting your complete application documents via our online application portal. For more information, please visit our homepage at www.bi.mpg.de.                               MAX PLANCK INSTITUTE FOR BIOLOGICAL INTELLIGENCE Am Klopferspitz 18 | 82152 Planegg, Martinsried Eberhard-Gwinner-Strasse | 82319 Starnberg - Seewiesen

Carl Zeiss Research Microscopy Systems
Sales and Marketing Intern
Multiple, California, Delaware, Pennsylvania, New Jersey, Oregon, Massachusetts, Virginia, Maryland, North Carolina, Texas, Minnesota, Illinois, "Washington, DC (District of Colombia)", New York, Wisconsin, Washington
USA

About Us: ZEISS Microscopy is the world's only one-stop manufacturer of light, electron, X-ray and ion microscope systems and offers solutions for correlative microscopy. The portfolio comprises of products and services for life sciences, materials and industrial research, as well as education and clinical practice. With its unique portfolio, constant innovations and strong partnerships, ZEISS Microscopy enables leading researchers to find answers to our society’s most pressing challenges and drive scientific discovery forward. A dedicated and well-trained sales force and a responsive service team enable customers to use their ZEISS microscopes to their full potential. Carl Zeiss Research Microscopy Systems (RMS) is the North American operation of the 177-year-old global organization, responsible for Sales, Service, Applications and Marketing for the United States and Canada.  To learn more about ZEISS RMS, visit:  https://www.zeiss.com/microscopy/en/about-us.html Here's What You'll Do: Our goal is to introduce students (later undergrad, masters or PhDs) to career paths in industry related to the company’s sales organization including roles directly in sales as well those in technical support, instrument service, business development, marketing, product management, customer service and leadership. The program is designed to give interns a holistic view of career paths in the organization and work directly with colleagues with technical and advanced degrees. You also will have the opportunity to interact with leading scientists and get hands on experience with cutting edge imaging technologies. This is a remote role (i.e., relocation to a ZEISS facility is not required) with a high degree of travel including daily trips to customer labs to do field work with sales, service and application teams, extended time (1-2 weeks) at our ZEISS Microscopy Customer Center in Dublin CA and a final trip to our headquarters in White Plains NY. Candidate will have a designated mentor and supervisor for duration of internship. There will be a project you work to develop over the course of your internship with your mentor and the team members you work with. The final project presentation will be delivered to the ZEISS leadership team in White Plains at end of the internship and you may share this afterwards as your work product for the internship. In addition to the stipend, all travel expenses will be reimbursed.  Note: this is not a R&D, Engineering, Programming or production internship. Location/Region: This position can be in one of the following areas; Baltimore/Washington, New York, Boston, Chicago, Texas, Bay Area, San Francisco, or Los Angeles. Do you qualify:

  • Science or Engineering background; upper-level BS student or MS/PhD candidates.
  • MS Office and presentation skills.
  • Willingness to learn and work hands-on in a laboratory imaging environment.
  • Valid driver's license. Nice to Haves:
  • Familiarity with high-end microscopy, including laser scanning microscopy, and imaging techniques beyond simple image capture and manipulation.
  • Familiarity in biological applications and workflow solutions, including image analysis and bioinformatics. The hourly pay range for this position is $20.00 – $21.25. The pay offered for this role may be influenced by factors such as job location, scope of role, qualifications, education, experience, & complexity/specialization/scarcity of talent.
Carl Zeiss Microscopy, LLC
Marine Biological Laboratory Intern
Woods Hole, Massachusetts
USA

About Us: Carl Zeiss Microscopy, LLC supports 18 summer courses from May through August in 2024 at the Marine Biological Laboratory (MBL) in Woods Hole, MA consisting of students and faculty attending from 30+ countries around the world. The Zeiss Training Group Summer Interns at MBL are an integral part of our summer support structure. Once interns are oriented, their primary role is to support student and faculty image acquisition activities throughout the summer. This includes basic set up of widefield microscopes, an understanding of Kohler illumination, brightfield, phase contrast, DIC and fluorescence contrasting methods, troubleshooting basic hardware and software issues, as well as conveying an understanding of what constitutes a good scientific image and how to prepare for and carry out image analysis. 

Here's What You'll Do: This will be an opportunity to learn, operate and support more advanced systems as well, including laser scanning confocal microscopy, Airyscan and potentially other super-resolution techniques. MBL Interns must have good analytic and time management skills, and be detail oriented and conscientious. Additionally, be able to work closely with people from a diverse range of cultural and scientific backgrounds. Inventory and QC along with tracking of equipment is critical. An outgoing disposition is an advantage, with a willingness to proactively engage with faculty and students. Working in overlapping shifts will be essential, so enjoying a strong team environment but also being able to work independently, are both essential for a successful internship. Do you qualify?

  • Student currently enrolled in a Bachelor’s, Master’s or Ph.D. degree in biology, physics, optics, biochemistry or related field.
  • Skilled in microscopy, optics, and imaging with a focus or interest in biology.
  • Proficiency in computing hardware and software including Microsoft Office Suite (MS Word, MS Excel, PowerPoint).
  • Ability to work independently for periods of time.
  • Excellent verbal & written communication skills.​
  • Must be able to lift, using proper form and technique, up to 50 pounds.
  • Must be able and willing to work between 40 to 50 hours per week, including shift work.
  • Nice to Haves:

  • Experience with imaging and image analysis software preferred. The hourly pay range for this position is $15.50 – $17.00. The pay offered for this role may be influenced by factors such as job location, scope of role, qualifications, education, experience, & complexity/specialization/scarcity of talent.
Aalen University
Marie-Curie Doctoral Network PhD Position in Correlative Microscopy
Aalen, Germany
Europe
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Deadline: Apr 3, 2024

PUSH THE FRONTIERS OF LIFE SCIENCES – MICROSCOPY ACROSS SCALES. The Group of Prof. Dr. Walter at the Centre of Optical Technologies (ZOT) aims at developing novel correlative microscopy solutions to facilitate imaging across scales in life sciences – in close collaborations with regional industrial partners: We plan to combine advanced fluorescence microscopy with electron microscopy to visualize molecules within their subcellular context at high resolution using Correlative Light and Electron Microscopy (CLEM). Specifically, we envision a unique advanced super-resolution and volume CLEM workflow under cryo-conditions that allows us, together with our collaboration partners, to tackle specific biomedical research questions that could not be answered before due to the lack of accessible solutions. This is a highly interdisciplinary project between physics, engineering, optics, and life sciences, and we are looking for   A PhD Student (3 years, E13, 70%) within the EU-funded Marie Sklodowska-Curie Doctoral Networks Action under Horizon Europe   To help us tackle several biomedical showcase projects (from microplastics to nanoparticles for targeted cancer therapy) by building and applying novel CLEM techniques. This is an exciting position since it is part of a European network of 13 partners & universities that will host all PhD candidates during secondments. The project will give candidates the opportunity to work closely with different imaging modalities while allowing them to network with other candidates and other project supervisors: https://clexm.eu/   Key responsibilities & Qualifications For the implementation of the project, according to your skill set and interests, you will work on (1) building a cryo-super-resolution microscope, (2) establishing Focused Ion Beam Scanning Electron Microscopy (FIBSEM) for biological samples at Aalen University, and (3) setting up correlative (automated) workflows between the two imaging techniques.

How to apply If you are interested in R&D in advanced microscopy with different radiations (from light to electrons), biophotonics, biomedicine, and image & data processing and want to help push the frontiers in cell biology, we look forward to receiving your application (motivation letter, CV, 2 reference letters or contact list of referees, and any other relevant information). Please send in one pdf file to Andreas Walter [andreas.walter@hs-aalen.de] by April 3rd, 2024. For further information about the position please contact Prof. Dr. Andreas Walter.

Due to the tight deadline, we prefer applicants that do not require a visa/working permit for Germany (i.e., EU citizens).

Max Perutz Labs Vienna - Central Facility BioOptics
Imaging Specialist
Vienna, Austria
Europe
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Deadline: Apr 8, 2024

Your role Your primary responsibilities will include: - Supervision of available top-notch light microscopy related systems (spinning disc and superresolution microscopy), including o training of users o overall maintenance (inclusive system calibration) o on-demand troubleshooting o user communication o all other aspects of experimental support to researchers (e.g. sample preparation; development of complex experimental workflows; data processing and analyses) ⎯ Involvement in every day’s facility operation: o Instruction/Service of users and maintenance of the instruments (= collaborative team effort) o Evaluation of techniques and data, as well as optimization of resources o Administration (statistics, surveys, homepage) o Assistance in organizing workshops/demos and core-promotion and outreach-initiatives ⎯ Academic Teaching (lectures, practical courses)

University of Sussex
PhD Engineering Scholarship: Laser Technologies in Medical Applications
Falmer, Brighton, UK
Europe
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Deadline: May 31, 2024

The university of Sussex is offering a a 3.5 year Engineering PhD scholarship based in the High Precision and Optical Metrology research lab led by Dr Rodrigo Aviles-Espinosa.

What you get You will receive a tax-free stipend at a standard rate of £19,237 per year and your fees will be waived (at the UK, EU, or International rate). In addition, to a one-off Research and Training Support Grant of £2,000.

PhD project Description: Within the last two decades, multiple efforts have been focused on introducing robotic surgeries in routine procedures including ophthalmology, urology, gynaecology, cardiology, etc. Current commercial robotic systems allow the surgeon to manipulate laparoscopic tools with millimetric precision. However, specialized procedures such as reconstructive microsurgeries, surgical anastomosis, vitreoretinal eye surgery, neurosurgery etc have not yet benefited from robotic surgery given the requirement for sub-millimetre precision considering both the robotic system and surgical tools. This project will bring the fields of ultra short-pulsed laser surgical tools development with high precision robotics to develop the future optical surgical devices delivering submillimetre accuracy for those structures present in specialized procedures (i.e. blood vessels, nerves, cells).

The researcher will design, develop, and test novel laser based surgical devices which will be fully integrated in our existing high precision robotic devices to address the above-mentioned challenges. This will be carried out by:

*Designing optical devices for optimum laser beam delivery considering the surgical task requirements. *Building optical probes capable of providing visualization and manipulation suited for a given micro-surgical task. *Assessing the performance of the developed tool to propose enhancements. *Integrating the optical tool with our high precision robot. *Analysing complex sets of big-data images to extract relevant information using automated strategies.

https://www.sussex.ac.uk/research/centres/robotics-and-mechatronic-systems/research/rodrigo

Eligibility This scholarship is available to UK, EU and overseas applicants. Eligible candidates will have an upper second-class (2:1) undergraduate honours degree (or equivalent qualification) in Physics or Physics Engineering. In addition, to having obtained an an internationally recognised master’s degree (or evidence of its completion in the nearest future) in Physics, Bioengineering, Electrical Engineering or a related field.

Required areas of knowledge in: *Optics and implementation of optical setups and Zemax simulation *Control software and programming skills (LabView, NI-RIO, NI-DAQ, etc.) *Image processing (image J, Matlab, etc) *CAD design.

It will be evaluated favourably if the candidate has experience in spectroscopy and microscopy techniques, and in handling/developing tissue phantoms. Likewise, it will be desirable for the candidate to demonstrate good communication skills and command of the English language. The candidate should hold appropriate expertise from their studies or MSc project to contribute to the research field described above.

The University of Sussex believes that the diversity of its staff and student community is fundamental to creative thinking, pedagogic innovation, intellectual challenge, and the interdisciplinary approach to research and learning. We celebrate and promote diversity, equality and inclusion amongst our staff and students. As such, we welcome applicants from all backgrounds.

Number of scholarships available 1

Deadline 31 May 2024 0:00 How to apply Apply online for a full time PhD in Engineering (SEP2024) using our step-by-step guide.

Please clearly state on your application that you are applying for the Laser Technologies in Medical Applications Scholarship under the supervision of Dr Rodrigo Aviles-Espinosa.

Please ensure you application includes each of the following:

1)A research proposal. For guidance on preparing your proposal, please see here. 2)Degree certificates and transcripts. 3)References, including a minimum of 2 from any institution studied at within the last 5 years. 4)If your first language is not English you will need to demonstrate that you meet the University’s English language requirements, see here for details of our accepted documentation. Contact us For general enquiries, please email phd.engineering@sussex.ac.uk.

For project specific queries, please email r.aviles-espinosa@sussex.ac.uk.

Timetable Application deadline: 31st May 2024 00:00 GMT

Interviews: Mid June 2024

Offers issued to successful candidates: By the 1st July

PhD entry: 16th September 2024

UCL
Post-doctoral research associate in the biophysical characterisation of genomic medicines
London, UK
Europe

The key objective is to determine how the properties of adeno-associated virus (AAV), such as serotype, capsid stoichiometry, and transgene length, impact the quantity and types of impurities generated. The goal is an improved understanding of the properties of AAV during bioprocessing and how its attributes impact the types of impurities generated. This work will use cutting-edge biophysical techniques, including UCL's time-resolved intrinsic-fluorescence lifetime extraction (TRIFLE) technology, and Cytiva's resin technologies as tools to separate and identify impurities which will then be characterised off-line using a range of techniques including: ddPCR, capsid ELISA, cell-based infectivity assays, and biophysical techniques such as differential scanning fluorimetry, dynamic light scattering and electron microscopy, as appropriate. Further work will address AAV process-related impurities and characterise non-AAV gene therapies including lipid nanoparticle and cell-free synthesis processes.

Bowling Green State University
Assistant Professor
Bowling Green, Ohio
USA
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Deadline: Apr 1, 2024

The Department of Biological Sciences invites applications for a tenure-track assistant professor position with a start date of August 2024. This is a full-time, 9-month appointment for individuals with demonstrated research experience in molecular or physiological processes with relevance to biomedical applications.

Center for Scalable Data Analytics and Artificial Intelligence Dresden / Leipzig (ScaDS.AI) at Leipzig University
Research Software Engineer (m/f/w)
Leipzig, Germany
Europe

About us

Founded in 1409, Leipzig University is one of Germany’s largest universities and a leader in research and medical training. With around 30,000 students and more than 5000 members of staff across 14 faculties, it is at the heart of the vibrant and outward-looking city of Leipzig. Leipzig University offers an innovative and international working environment as well as an exciting range of career opportunities in research, teaching, knowledge and technology transfer, infrastructure and administration. The Center for Scalable Data Analytics and Artificial Intelligence Dresden / Leipzig (ScaDS.AI) at Leipzig University seeks to fill the above position at the earliest opportunity. ScaDS.AI Dresden/Leipzig is expanding the national competence center for Big Data, ScaDS, which was founded in 2014. With our research, we aim to bridge the gap between the efficient utilization of massive data and advanced AI. We are developing new methods of machine learning, knowledge management, and methods for preserving privacy. In cooperation with a variety of users from the fields of science and industry, we transfer the developed techniques to various application areas. ScaDS.AI is a research center for Data Science, Artificial Intelligence, and Big Data with locations in Leipzig and Dresden. Both sites are affiliated with a local university - the University of Leipzig and the TU Dresden. As one of five new AI centers in Germany, ScaDS.AI originates back to 2014 and is funded funded since 2019 as part of the federal AI strategy, supported by the Federal Ministry of Education and Research and the Free State of Saxony. You will become part of the German National Research Data Management Initiative for Bioimaging Data (NFDI4BioImage, https://nfdi4bioimage.de/). NFDI4BioImage will strive to provide scientists from all natural science and biomedical research fields with workable and trusted solutions to handle the ever-increasing amount of bioimage data from the various (light) microscopy techniques and related biophotonic technologies. Bioimaging data should thus be in accordance with the FAIR principles, i.e., be Findable, Accessible, Interoperable, and Re-Usable. Increasing data accessibility and re-usability will advance bioimage informatics, the scientific discipline devoted to quantitative analysis and software-aided knowledge extraction from bioimage data. Within this nation-wide network we are responsible for setting up a database and search engine for training materials. About the position

  • Fixed term of 3 years
  • 100 % of a full-time position. In principle, the position is also suitable for part-time employees. Please note this preference in your application.
  • Planned remuneration: salary group E13 TV-L

    Duties

  • designing a search index consisting of a database, a search engine and website for Research Data Management, Bio-image Analysis and Data Science related training materials
  • implementing and maintaining the software solution
  • interacting with developers of similar platforms such as bio.tools, biii.eu and microscopydb.io to make sure our resource is interoperable with these platforms.
  • interacting with NFDI4BioImage members and participating scientists guiding them in using our platform
  • developing strategies for involving the scientific community in curation and maintenance of the resource
  • presenting the resource on national and international conferences

    Requirements

  • University degree in data science, computer science, software engineering or related fields
  • English and German communication skills (B2)
  • Experience with web development (e.g. Drupal, sphinx, Javascript, HTML)
  • Experience with ontologies and databases (e.g. EDAM, SPARQL, SQL)
  • Experience in Python programming
  • Experience in open-source software development is a plus

    What we offer

  • A modern workplace and attractive working conditions
  • Flexible working hours and work-life balance
  • Goal-oriented staff development throughout your working life, with opportunities for continuing professional development
  • Pension plan
  • a discounted local public transport ticket (e.g. the Deutschlandticket as a job ticket) Please upload your application as a single PDF file. Please note that it is not possible to guarantee confidentiality and rule out unauthorised access by third parties when communicating by unencrypted email. We kindly request that you submit copies only, as we are unable to return application documents. Interview expenses will not be reimbursed. Questions about the position can be addressed to: Dr. Robert Haase, robert.haase@uni-leipzig.de . 0341 97 39309   Leipzig University aims to increase the proportion of women in positions of responsibility and therefore expressly invites qualified women to apply. Severely disabled persons – or persons deemed legally equal to them under Book IX of the German Social Code – are encouraged to apply and will be given preference in the case of equal suitability. 

    Kontakt

    Universität Leipzig Robert Haase Humboldtstraße 25 04105 Leipzig

Tel. 0341 97 39309

Indiana University School of Medicine
Asst / Assoc / Professor of Medicine
Indianapolis, Indiana
USA
The Indiana University School of Medicine is seeking a faculty member at any rank for a tenure track position.  The candidate should be a creative, independent and energetic individual to direct the Indiana Center for Biological Microscopy (ICBM), a 25-year-old core facility whose mission is to promote the effective use of advanced forms of optical microscopy by Indiana University researchers. 
 
The Director will lead a team that provides state-of-art microscopy capabilities to more than 70 Indiana University investigators,100 NIH-funded projects and 3 NIH Centers.  As described on the Center website, (http://web.medicine.iupui.edu/icbm/) the ICBM is equipped with two Leica confocal/multiphoton microscopes, an Olympus confocal/multiphoton microscope, an ISS Fast-FLIM/confocal system, a Nikon live-cell spinning disk confocal microscope, two Akoya Phenocycler (CODEX) multiplexing microscope systems and a Keyence BZX800 high-content/high-throughput imaging system.  Quantitative image analysis is supported with four computer workstations devoted to image analysis (Metamorph, FIJI, Autoquant, Imaris, Halo and Amira).
 
A major focus of the Center is to extend services beyond conventional microscopy, to help investigators implement powerful, but challenging imaging methods, including intravital microscopy, 3D tissue cytometry and advanced methods of image and data analysis.  This is a tenure-track position, and while individuals with funded research programs are welcome to apply, promotion and tenure will primarily be evaluated by the success of the director in the missions to (1) ensure that the ICBM supports the microscopy needs of Indiana University investigators, and (2) actively identify and implement powerful new techniques that will extend their research capabilities.  In addition to a strong background in microscopy and image analysis, successful candidates are expected to have excellent interpersonal skills, and a sincere commitment to customer service.
 
The successful candidate will be expected to
1.    Oversee Center operations, supervising two full-time PhD imaging specialists, who manage Center services, equipment maintenance, system repairs and service billing.
2.    Interact and collaborate with an active community of researchers; provide expert advice in experimental design, facilitate development of new techniques and participate in the preparation of manuscripts.
3.    Contribute to proposals for research funding; help researchers identify appropriate imaging approaches, facilitate the collection of crucial preliminary data and provide text and letters of support.
4.    Develop and realize a strategic vision for service development based upon advances in technology and the evolving needs of the Indiana University research community.
5.    Prepare internal and external grants for acquisition of new imaging equipment. 
6.    Promote the development and support the operation of novel microscopy cores for NIH Center grants.
7.    Promote the opportunities of the Center through targeted seminars presented to IU research groups.
8.    Develop informational materials and teach in microscopy workshops.
Micrographia Bio
Engineer in Optical Microscopy
London
Europe

Description

Our mission at Micrographia Bio is to deliver a new era of drug discovery using spatial proteomics. We are adding an Engineer in Optical Microscopy into our multidisciplinary team. This role will be responsible for the design, assembly, maintenance, and validation of our optical imaging systems. The successful candidate will join a world-class team that is united by an intrinsic motivation to develop first-in class technology and new medicines. We hire people who do brilliant work and 10X the work of the people around them. As an early team member, you’ll have a major influence over the direction of the company. We’re looking for people who do stunning work. In return we’ll give you an opportunity to grow and develop in a place that’s fun, supportive, and unrelenting in its pursuit of world-class “DeepTech” technology, all while sharing in the success of the company. We think this is a great opportunity for an industrial microscope engineer who is looking to apply their engineering expertise in a start-up industry environment, here in London. If consider building microscopes that unravel biology to be your professional craft, this might be the perfect role for you.

Responsibilities

  • Design, build, and characterise of advanced light microscopy systems that drive our technology forward (e.g. optical design, hardware control)
  • Collaboratively carry out the design, the acquisition and the analysis of large-scale microscopy experiments in the context of drug discovery
  • Communicating theoretical, practical, and experimental knowledge to the company spanning several disciplines (software, AI, commercial)
  • Working closely with our inter-disciplinary team to establish integrated fluorescence imaging strategies
  • Proactively contributing to a positive, enthusiastic, collaborative engineering culture

    Requirements

    Must haves

  • PhD in a relevant technical field (e.g. biophotonics, optics), or equivalent practical experience (advanced microscopy development)
  • Experience in assembling / customising fluorescent microscopy imaging systems for specific experimental purposes
  • Strong practical and theoretical understanding of optical engineering and fluorescence microscopy
  • Ability to think critically and adapt in a fast-paced start-up environment
  • Excellent technical communication skills

    Should haves

  • Experience in super-resolution microscopy, especially single-molecule imaging
  • Software development experience - version control, unix, docker, cloud operations
  • Knowledge and experience with Python programing language
  • Basic knowledge of cell and molecular biology
  • Post-doctoral or industry experience
  • Experience in microfabrication

    Nice to haves

  • Previous start-up experience
  • Experience in core light microscopy facility
  • Experience in robotics / control theory

    Benefits

    Salary

  • Industry Competitive Salary
  • Equity options to share in the company success

    Benefits

  • The chance to revolutionise the way we find new drugs and increase probability that you will help discovery drugs that matter with your skillset
  • Company matched pension, private healthcare cover, and life insurance
  • Fully stocked kitchen with breakfast and snacks
  • State-of-the-art London zone 2 working location and laboratories
  • The opportunity to work with global thought leaders on our Scientific Advisory Board
  • Access to Bubble for Work - for care needs of young children, elderly care, pet care. People first - a culture enabling you to do your best work
  • Access to the Cycle-To-Work scheme (including access to secure cycle storage, showers, changing rooms on-site)

    Disclaimers

    Micrographia Bio welcomes applications from all candidates irrespective of age, disability, gender, gender identity, sexual orientation, race, religion or belief, or marital or civil partnership status. If you have a career gap on your CV, but feel motivated by the job description to apply with your skills, we highly encourage your application.

Institut Pasteur
Engineer in image analysis
Paris, France
Europe
Learn More
Deadline: May 31, 2024

Our research group (Cell Death and Epithelial Homeostasis unit in Institut Pasteur) is seeking a engineer for image analysis (permanent position) to help us developing pipelines for 4D movies analysis and adapt/maintain pipelines previously developped by the group to share them with a large audience. More information can be found here : https://research.pasteur.fr/en/job/image-analysis-engineer-permanent-position-cell-death-and-epithelial-homeostasis-group-institut-pasteur/

Institut Pasteur
Image analysis engineer position Institut Pasteur/Cell Death and Epithelial Homeostasis group (permanent position)
Paris, France
Europe
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Deadline: May 31, 2024

Our research group (Cell Death and Epithelial Homeostasis) located in Institut Pasteur (Paris, France) in the department of Developmental and Stem Cell Biology is seeking an engineer in image analysis to join our group through a permanent position, ideally to start in September 2024.

Our group is interested by the fine tuning of cell death in epithelial context using mostly Drosophila as a model system (https://research.pasteur.fr/en/team/cell-death-and-epithelial-homeostasis/)..%20) We use a wide range of live imaging technics and develop new tools (including live sensors and optogenetics) to dissect quantitatively the feedback fine tuning cell death. Our group has been developing over the years various pipelines (z reconstruction, segmentation and tracking, automatic recognition of cellular events through deep learning, force inference…) and is looking for a stable support that will help us to:

-      Develop new pipelines for image analysis mostly for 4D movies (PIV, segmentation, tracking, force inference, features extractions…) -      Maintain and update pipelines previously developed by the group -      Survey newly published methods and adapt them for our needs -      Assist us in the quantitative analysis of our datasets -      Help us to maintain and share our pipelines with a large public through the development of user friendly codes and visual interfaces -      Train the members of the unit for good practice in data management, code writing, metada maintenance and data sharing We are looking for a candidate with good coding knowledge (mostly Python, but also Matlab and Java), good theoretical knowledge of fluorescent live imaging, expertise in machine learning applied to image analysis, a real interest for collaborative work, capacity to work on several projects in parallel and with good listening capacity. The applicant will join a dynamic and supportive group that promotes healthy work life balance, with members coming from various backgrounds, and located in a collegial and vibrant department. The application will also get close interactions with the growing community of image analysts on campus.

If you are interested, please, send a single pdf document with CV, cover letter, Github/Gitlab link, and reference contact to romain.levayer@pasteur.fr (with the subject “engineer position”).

The official job advertisement can be found in the following link: https://emploi.pasteur.fr/job/emploi-ingenieur-en-analyse-d-image-et-donnees-quantitatives-h-f_11427.aspx?LCID=2057

Relevant references: Matamoro-Vidal, A., Cumming, T., Davidovic, A., and Levayer, R. Patterned apoptosis modulates local growth and tissue shape in a fast-growing epithelium. Current Biology 34, 1-13, https://doi.org/10.1016/j.cub.2023.12.031 (2024) Villars, A., Letort, G., Valon, L. & Levayer, R. DeXtrusion: automatic recognition of cell extrusion through machine learning in vivo. Development 150 (13) doi: https://doi.org/10.1242/dev.201747 (2023). Villars, A., Matamoro-Vidal, A., Levillayer, F. & Levayer, R. Microtubule disassembly by caspases is an important rate-limiting step of cell extrusion. Nat Commun 13, 3632, doi: https://doi.org/10.1038/s41467-022-31266-8 (2022). Herbert S.*, Valon L.*, Mancini L., Dray N., Caldarelli P., Gros J., Esposito E., Shorte S.L., Bally-Cuif L., Aulner N., Levayer R., Tinevez J.Y., LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images., BMC Biol 2021 Jul; 19(1): 136, doi: https://doi.org/10.1186/s12915-021-01037-w (2021). Valon, L., Davidovic A., Levillayer, F., Villars, A., Chouly, M., Cerqueira-Campos, F., & Levayer, R.* Robustness of epithelial sealing is an emerging property of local ERK feedback driven by cell elimination. Developmental Cell 56, 1-12. doi: https://doi.org/10.1016/j.devcel.2021.05.006 (2021).  Moreno, E., Valon, L., Levillayer, F. & Levayer, R. Competition for Space Induces Cell Elimination through Compaction-Driven ERK Downregulation. Current Biology, 29, 23-34 e28, doi: https://doi.org/10.1016/j.cub.2018.11.007 (2019). 

Salk Institute for Biological Studies
Postdoctoral Fellow - Fluorescence Lifetime Microscopy
La Jolla, California
USA

Postdoctoral position developing a fluorescence lifetime microscope for in vivo imaging of neuron activity and signaling at kilohertz rates. We are developing custom optical systems using electro-optic fluorescence lifetime microscopy (EO-FLIM) to enable fast and quantitative imaging of cellular signals in 3D environments. This work will combine FLIM instrument development, lightsheet microscopy, and applications imaging fluorescent biosensors in vivo.

Yale School of Medicine
Senior Staff Scientist (85998BR)
New Haven, Connecticut
USA
Learn More
Deadline: Jul 31, 2024

Position Focus: Senior Staff Scientist position available in the FIB-SEM Collaboration Core (F-SCC) (https://medicine.yale.edu/fib-sem/) of Yale School of Medicine. At the forefront of volume Electron Microscopy, the F-SCC utilizes the state of the art enhanced Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) technology for large volume imaging with nanometer isotropic resolution. Under supervision of the Director of F-SCC, the candidate will play a leadership role in managing enhanced FIB-SEM sample preparation and image acquisition lab within F-SCC. Explicitly, the candidate will be responsible for pipeline processes of X-ray guided FIB-SEM sample preparation, enhanced FIB-SEM image acquisition, and image registration and alignment. The candidate is expected to be multi-tasking, perform independent experiments using the state-of-the-art laboratory techniques including electron, X-ray, and light microscopes. The candidate will work closely with supervisor, group members, and collaborators. While the job duty will evolve according to the needs of the organization, specific responsibilities include: 1.    Perform FIB-SEM sample preparation: mount and trim heavy metal-stained and resin-embedded samples to target specific region of interest using an ultramicrotome guided by X-ray micro-CT. 2.    Perform FIB-SEM image acquisition using customized enhanced FIB-SEM microscopes. Optimize imaging conditions for the best results. Maintain equipment and troubleshoot hardware and software related issues. Perform system installations and upgrades when needed. 3.    Perform 3D image registration and alignment. 4.    Perform IT related system administration duties to maintain image analysis and data storage platform.   Dept/Section URL Click here for more information   Essential Duties 1.    Carries out the wide range of specialized scientific methods and procedures used in the laboratory. 2.    Responsible for resource planning, allocation, and planning renovations. Determines, develops, and implements the operative framework of the laboratory as it relates to long-term goals, needs, and direction. 3.    Keeps abreast of newly-evolving technologies, instrumentation, and methodologies and purchases new instrumentation. 4.    Develops, analyzes, interprets, and summarizes scientific results. 5.    Establishes policies and procedures governing operation of the laboratory. 6.    Independently investigates and solves biotechnological problems as they arise through research and extensive literary searches. Determines subsequent experimental approaches. 7.    Independently decides when additional analyses are needed, arranges for the needed analyses and interprets the resulting design and implements customized protocols. 8.    Authorizes and organizes the use of laboratory and equipment to ensure timely completion of research projects. 9.    May perform other duties as assigned.   Required Education and Experience Master’s Degree in experimental physics, physical chemistry, engineering, or other related discipline and five years of experience or an equivalent combination of experience and education Required Skill/Ability 1: Proficiency in complex instrumentation operation, maintenance, and troubleshooting. Required Skill/Ability 2: Proven dexterity in manipulating small objects and demonstrated ability in three-dimensional thinking. Required Skill/Ability 3: Proficiency in software coding. Familiar with Windows and Linux operating systems. Ability to maintain computers and troubleshoot hardware and software related issues. Ability to learn and carry out IT related system administration duties. Required Skill/Ability 4 Proven ability to search and interpret scientific papers, protocols, standard operating procedures, safety standards, maintenance instructions and procedure manuals for laboratory equipment. Required Skill/Ability 5: Demonstrated capability to manage laboratory facilities and workspaces. Proven ability to plan project needs to optimize resources necessary for successful project completion.   Preferred Education, Experience and Skills: Ph.D. degree in experimental physics, physical chemistry, engineering, or other related discipline, plus six years of relevant experience. Special considerations will be given to those who have expertise in LabVIEW, Python, and MATLAB. Experience in database management (MySQL) and virtual machine environments (VMware ESXi) is a plus.

Institute of Science and Technology Austria
Microscopy Internship
Klosterneuburg (near Vienna), Austria
Europe

Internship Microscopy

  • Full Time (40 h/w)
  • Klosterneuburg near Vienna, Austria
  • € 1,906 to € 2,044* gross/month depending on level of education - 3 to 6 months (start in April)

    Your Responsibilities

    The Imaging and Optics Facility of ISTA provides state-of-the-art fluorescence microscopy services, flow cytometry services, as well as custom image analysis and optical development services. As an intern in our team, you will support our scientists in carrying out their research work:

  • Contribute to general core facility and infrastructure tasks, including routine facility checks, inventory checks and control of facility (loan) equipment
  • Support in basic operation of microscopy equipment
  • Assist in standard quality monitoring and performance checks
  • Optional: “project involvement” in optimisation of calibration standards and optical maintenance protocols AND/OR involvement in development of advanced imaging controls toolbox (depending on applicant qualification)

    Your Profile

  • Completed BSc or enrolled in MSc in Physics, Life Science or Neuroscience (or equivalent)
  • Basic knowledge in microscopy techniques (e.g. Brightfield, Fluorescence, Confocal)
  • Basic knowledge of programming languages (e.g. FIJI macro, Matlab, Python) of advantage
  • High level of interest in the Imaging and Optics Facility services
  • Knowledge of programming/scripting languages (e.g. C, Python) required for “project involvement” in development of advanced imaging controls toolbox
  • Strong affinity with Optics, Electronics and Programming of advantage for “project involvement”
  • Service-oriented and conscientious approach to work
  • Eager to learn, proactive personality and team player
  • Ability to independently take over small projects
  • Good command of English (Institute language)

    ISTA is growing. Grow with us!

    Institute of Science and Technology Austria (ISTA) is a constantly growing international institute for conducting frontier research in mathematics, computer science, life sciences & physical sciences. We strive to recruit passionate professionals from across the world over all fields who strive to support our goal of excellent research. Located within a beautiful campus on the outskirts of Vienna, we offer multiple opportunities for personal growth in a stable working environment. Get an insight! *This position comes with possible overpayment depending on education, qualification and work experience. For more information on how ISTA processes your personal data, please refer to www.ista.ac.at/data-protection.

Ecole Polytechnique/CNRS
Postdoc in optical microscopy: developement of fast FLIM approaches
Palaiseau, Ile de France, France
Europe
Learn More
Deadline: Mar 31, 2024

Post-doctoral position on " Fast Fluorescence Lifetime with Light Sheet Microscopy for metabolic imaging of zebrafish embryos and brain organoids"

University of Copenhagen
Light Microscopy SR applications specialist at Core Facility for Integrated Microscopy
Copenhagen, Denmark
Europe
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Deadline: Apr 1, 2024

Applications are invited for a permanent position as Light Microscopy Applications Specialist at the Core Facility for Integrated Microscopy (CFIM), the Faculty of Health Sciences, University of Copenhagen, to commence as soon as possible, preferably no later than 1 April 2024.

Zeiss Group
Product Application Sales Specialist (PASS) Protégé - Light Microscope
Pleasanton, California, Illinois, Missouri
USA

Join ZEISS as a Product Application Sales Specialist (PASS) Protégé and be immersed in the latest cutting edge scientific technologies and interact with leading scientists and their exciting research projects. This position is a remote home-office position from St. Louis, MO, Chicago, IL, or Silicon Valley/San Francisco Bay Area.

The ZEISS Product Application Sales Specialist (PASS) Protégé is a 6 - 12 month training program designed to prepare you to step into a highly technical, specialized role within the company that requires extensive product and application knowledge coupled with persuasive communication and sales skills. The protégé position requires active support for product applications, front line sales (Account Managers), and customers with a focus on guiding customers to ZEISS solutions, contributing to and creating customer value and facilitating customer success working both independently and in a team dynamic. During the program, you will receive in - depth training on a variety of scientific and application areas including: Microscopy, 3D Imaging, Research Applications, Image (data) Analysis and Visualization, End-to-End Solutions, Customer Retention, Training, and Support with the Zeiss Selling Process (ZSP). 

Upon successfully demonstrating mastery of key metrics (ZEISS Sales Process, Deep Understanding of Application Space, Operating Microscope Portfolio, understanding of the ZEISS network), the protégé may be offered an opportunity to transition into a PASS role or another specialized function. You will have proficiency milestones established to measure success and advance them through the development process. These Key Performance Indicators (KPI) will be assigned, and they will be relevant, achievable, and measurable.

Primary Duties and Responsibilities:

  • Attend basic and advanced training courses to prepare for a sales role at ZEISS.
  • Shadow and support experienced Account Managers, Sales Specialists, & Application Specialists, as well as participate in customer visits.
  • Expect to attend weekly 1:1 review(s) with the reporting manager for scheduling, debriefing, planning, strategic discussion and knowledge sharing.
  • Actively support the field sales organization with product demonstrations, training and installation, presentation generation, quote generation, data analysis and visualization, remote trainings, content creation of system/widefield workflows, sample analysis and runs, and other field sales activities.
  • Attend on-site customer visits and support of ZEISS equipment.
  • Attend trade shows, conferences, and customer workshops exposing them to cutting edge research and technologies.
  • Be exposed to new product technologies and launches.
  • Protégé will familiarize themselves with equipment installation processes, and ensure that they understand the aspects of expectation setting.
  • Manage MS Teams/MS Office, TeamViewer, Go-to-Assist, and SAP/CRM amongst other sales enablement tools and be trained in-depth during the first three months of onboarding.
  • Be responsible for your personal safety when visiting labs and institutions by understanding the basics of lab behavior and an awareness of risks (BSL 1 - 4).
  • Control direct expenses via strategic planning and employing cost effective measures to their regional business.

Experience and Education Requirements:

  • Undergraduate degree or higher in biological science or bio-engineering from an accredited college or university.
  • Knowledge and experience in biological applications and workflow solutions, including image analysis and bioinformatics a huge plus.
  • Good knowledge of software for post- acquisition analysis such as quantification, visualization, correlation, coding/scripting, and other microscopy based solutions is a plus.
  • Be able to travel 50% or more during the program.
  • Working knowledge of Widefield and/or Confocal Imaging a plus.
  • Strong written and verbal communication skills.
  • Positive “can do” attitude coupled with a willingness to continuously acquire product and application knowledge independently.
  • Energetic, results-driven with excellent organizational, time management and prioritization skills.
  • State issued valid driver’s license.

The annual pay range for this position is $70,000 - $72,000.

The pay offered for this role may be influenced by factors such as job location, scope of role, qualifications, education, experience, & complexity/specialization/scarcity of talent.

This position is also eligible for a performance bonus or sales commissions.  ZEISS also offers robust benefits, including medical plans, retirement savings plan and paid time off.

The University of California: San Francisco
Biological Imaging CoLab Director
San Francisco , California
USA
Learn More
Deadline: Jan 21, 2025

We are recruiting a new director for the Biological Imaging Development CoLab (BIDC) at the University of California in San Francisco.

CoLabs (http://colabs.ucsf.edu/) is a new model for supporting collaborative research at UCSF. The BIDC is one of five CoLabs teams with specialized research and technical expertise in analyzing biological samples using various approaches. These teams work together closely and collaborate with a large group of investigators in many UCSF departments. BIDC’s missions include microscopy education, training, consulting, and technical support and microscopy research and development.

The BIDC Director role is multifaceted and requires independence, initiative, organization, and flexibility. The incumbent must have experience in biological-related microscopy research, strong interpersonal skills to work closely with investigators, students, postdoctoral fellows, visiting scholars, and staff members, and strong time management skills. The incumbent also must have strong mentoring and leadership skills.

In general, the BIDC Director’s activities will include, but are not limited to: maintenance and management of the Biological Imaging Development CoLab’s (BIDC) microscopes and support equipment; training and assisting new users on microscopes, techniques, and data analysis; assisting in experimental design and analysis pipelines; direct supervision of two or more employees; oversight of CoLab’s budget including salaries and materials; coordinating team members for new initiatives and projects; and the mentoring and career development of co-workers. The BIDC Director is also responsible for keeping the facility current with trends and needs of the microscopy community. This is accomplished either through the raising funds and purchasing commercial equipment, designing and developing technology, or adding new support resources for the research community. The incumbent will report directly to the Director of the CoLabs and the BIDC Steering Committee.

Required qualifications:

A PhD in natural sciences; biology, chemistry, physics, or related discipline. At least 5 years of experience in microscopy-based instrument development. At least 5 years of experience in high-dimensional microscopy data analysis. At least 5 years of experience in biology specific microscopy techniques and analysis. Proficiency in microscopy data analysis using available software such as Imaris, Elements, LAS, FIJI, ImageJ, and Ilastik. Demonstrated skills and experience in teaching and mentoring graduate students and professional trainees. Strong interpersonal skills and the ability to work with individuals from diverse backgrounds. Strong time management skills and demonstrated attention to details. Preferred qualifications:

Excellent written and verbal communication including writing of research manuscripts, and scientific oral presentations (in-person and virtually). Experience in preparing grant proposals, especially shared equipment grant proposals. Experience in management of a shared research resource or core facility. Proficiency in custom microscopy data analysis using Matlab and Python. Hands-on experience in confocal, widefield, light-sheet, and super-resolution microscopy techniques. Experience in computer assisted drawing (CAD) for instrument design and development. Experience in electrical circuit design with soldering skills.

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