This position will manage the Microscopy Imaging and Analysis Core (MIAC), funded by a COBRE Project grant from the National Institutes of Health. The manager will manage the facility, train and directly assist investigators in confocal microscopy and image analysis, design experiments utilizing confocal imaging and analysis, network with industry and academic experts, maintain equipment, direct internet outreach, and develop the MIAC’s capabilities. Typical hiring range is $55,000 to $67,000 commensurate with qualifications and experience.

A postdoctoral research position to study Epithelial Membrane Domain Organisation is available in the Stefan laboratory at the LMCB at UCL. We are seeking a highly motivated and creative scientist to contribute to an exciting research programme investigating vital roles of inter-organelle cross talk in the regulation of membrane domain organisation in epithelial cell architecture. The successful candidate will be part of a highly collaborative research team studying membrane domain organisation and mechanics in epithelial architecture, spanning electron microscopy, molecular membrane biology, biochemistry, biophysics and computational approaches to model molecular membrane organisation.

We seek an aspiring microscopy technician to join the Electron Microscopy Core Facility ​​​​​​​in the Faculty of Biology, Medicine, and Health. The primary focus of the role will be to conduct and to contribute to development of electron microscopy approaches including volume electron microscopy and correlative light and electron microscopy techniques. The post holder will also optimize protocols for improved sample preparation. The microscopes are held with excellent core facilities for Histology/Bioimaging and Electron Microscopy and the role holder will work closely with facility staff, learn new techniques they are not familiar with, attend training courses and techniques development workshops   The role is for an initial period of 3 years with a view to it becoming a permanent post and therefore a positive and proactive approach is essential. This is a unique opportunity to join an innovative new research centre and it would be an ideal opportunity for a keen technologist to become part of a team and to develop powerful imaging techniques.

The extracellular matrix is a complex network of fibrillar proteins, glycoproteins and secreted factors that form complex assemblies essential for tissue structure and function. Different specialised mammalian tissues contain many of the same basic building blocks but organised in differently to provide their distinct properties. Most components of the extracellular matrix are large, insoluble multicomponent complexes which are extensively post-translationally modified. The aim of this project is to integrate the imaging of extracellular matrix complexes and fibrillar assemblies from the molecular to the tissue scale. Working with research groups across the Platform and Electron Microscopy Facility, you will develop imaging approaches such as correlative light and EM (CLEM) and volume EM for matrix tissue samples. This will involve using cell or tissue samples with fluorophore-tagged matrix components in addition to tissues with antibody/nanobody labelling.

A Bit About Us: We are Arcadia Science. Arcadia is a science company founded and led by scientists. Our mission is to transform evolutionary innovations into real-world solutions by openly developing more efficient, replicable, and sustainable ways to leverage the biology of diverse organisms.

The Opportunity:

We are seeking a highly collaborative and motivated scientist who is excited about statistical analysis of microscopy data and generating computational tools for biologists. With this hire, we plan to expand functionality in high-content image analysis and expand the predictive capacity of novel features from multi-modal data types. We are looking for someone who enjoys working in a team environment and responds well to the fast pace and iterative nature of experimental work. Enthusiasm for open science is required as we publish our work in smaller units, quickly, and iteratively. 

The overarching goal of the Microscopy Team’s efforts at Arcadia is to enable discovery across the tree of life using label-free image-based experimental approaches. As a part of Arcadia’s Discovery Platform, we are pursuing tools and approaches that are highly adaptable and scalable as we build capacity for high-content imaging experiments across a wide range of organisms. Our Team aims to iterate on existing tools and build flexible pipelines for image processing and statistical analysis that will be deployed for different experimental needs, whether that is through collaboration with scientists at Arcadia or shared openly in the broader community. 

We believe there is untapped potential to extract quantitative information from data-rich videos of live organisms moving in 3D over time. Whether we are working with datasets generated in-house or from open-source data, our goal is to be able to input largely label-free images (DIC/Phase/autofluorescence), quickly get a sense of the distribution of data on many features in the image, and robustly test hypotheses through statistical analysis. 

Within 3 months, you should be able to develop computational pipelines that input raw microscopy data and process the data appropriately, extract quantitative metrics, and statistically evaluate the signal. You should feel ready to implement specific statistical analyses to evaluate the composition of high-resolution images in terms of fine features, volumes of specific shapes and sizes, and identify other signatures without a priori knowledge. You should be able to implement comparative analyses of the morphology and motility of cells/organisms from video data. 

Within the first 6 months, you may also enable new imaging approaches by combining computational algorithms with collecting different types of microscopy data. You may employ machine-learning models to analyze imaging data in high-throughput ways. Throughout this time, you will be solving analysis problems for different projects and collaboratively writing short publications on this work.

If you are a curious person with programming and analytical skills that sound complementary to these types of data, and have a strong background in statistical analysis, please review the responsibilities and answer the questions below. 

Responsibilities

- Designing and implementing computational pipelines for processing of biological data from microscopy images
- Applying appropriate statistical analysis methods for biological data 
- Processing and analyzing high-content microscopy images especially those that are label-free and high-throughput
- Collaborating with biologists and integrate user-feedback into the processing/analysis pipelines
- Communicating readily at different levels of technical expertise
- Applying statistical rigor to a variety of data
- Helping to design figures and write pubs

Education/Experience (Required)

- PhD in Computational Biology, Bioinformatics, Applied Math, Biology, Biomedical Engineering or a related field.
- Experience in image processing and scientific programming in Python (e.g. NumPy, SciPy, scikit-image, PyTorch, etc) and/or R, or MATLAB.
- A strong background in statistical analysis, ideally with biological data (e.g. multivariate models, waveform analysis, Fast Fourier Transform and spectral analysis, denoising and deconvolution algorithms).

Education/Experience (Preferred)

- A strong background in image processing including segmentation, object identification, quantification, and feature extraction.
- Experience in computational imaging and image reconstruction algorithms (e.g. quantitative phase, Fourier ptychography). 
- Experience with fluorescence microscopy, brightfield microscopy, DIC, phase, or other.
- Experience with video data as well as 3D stacks of images. 
- Experience building, maintaining, and using large-scale datasets.
- Excellent interpersonal and project management skills.
- Excellent written and oral communication skills.

Successful applicants can expect to be compensated between 125-150K with benefits and a highly competitive equity offering, depending on experience level. The scientist is part of the microscopy team, and reports to Tara Essock-Burns. The position will require the individual to be on-site at our Berkeley, California headquarters.

Application Process: Interested applicants should send a resume and a one-page cover letter that addresses their interest and qualifications for the position.

Arcadia Science is an equal opportunity workplace; we welcome people from all backgrounds and communities. We provide competitive compensation and practical benefits to keep you happy and healthy so that you can do your best work.

Please note that an offer of employment from Arcadia is contingent upon the successful clearance of a reference and background check.

Not specifically a microscopy job, but microscopy adjacent; this position is to support our volume EM efforts in neuroscience. Please refer all interested people to apply at the URL listed.

https://alleninstitute.org/careers/?p=2&jobId=45da560f-39ac-5d51-dbc0-52a1f26f4b4f#actively-seeking-passionate-people-6

Scientist I – Whole Brain Electron Microscopy - Imaging The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science. The mission of the Allen Institute for Brain Science is to accelerate the understanding of how the human brain works in health and disease. Using a big science approach, we generate useful public resources, drive technological and analytical advances, and discover fundamental brain properties through integration of experiments, modeling and theory. We are seeking a scientist to work on developing novel large scale Electron Microscopy (EM) approaches. The scientist will be responsible for scaling and automating the EM imaging of whole mouse brain sections across a mouse hemisphere. This will involve modifying Transmission Electron Microscopes (TEMs) to handle large sections (~ 1 cm2) and testing tomographic strategies. The goal of the research is to create the technologies to allow the complete mapping of synaptic connectivity of individual neurons across the entire mouse brain, something that has never been done before. The project will first apply this technology within the Cortico-Thalamic-Basal-Ganglia loop to discover cell types and test models of neural computations within this circuit. The scientist will be an essential member of the EM connectomics project studying cell types and will also have opportunities for data analysis in later phases of the project. We are a dynamic multi-disciplinary team with deep expertise in electron microscopy and contribute to cutting-edge research in the field! Our team has already cut and imaged multiple datasets with tens of thousands of sections, making it an exciting time to join and achieve the next level of impact and scaling. No previous sectioning experience is required, as we welcome enthusiastic applicants who are new to the field but possess a strong interest in automation and a passion for scientific progress. The team already includes several EM experts, and therefore also welcomes applicants that are new to electron microscopy but have a strong interest in automation and in the overall goals of the project. Examples of work related to this position can be found on: https://www.nature.com/articles/s41467-020-18659-3 https://elifesciences.org/articles/76534 https://www.cell.com/cell/pdf/S0092-8674(22)00134-9.pdf https://www.pnas.org/doi/10.1073/pnas.2202580119 https://www.biorxiv.org/content/10.1101/2021.07.28.454025v1 https://www.biorxiv.org/content/10.1101/2023.01.23.525290v1 The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

The Life Science Field Service Engineer is responsible for installing, servicing, and supporting the imaging systems product line, including but not limited to confocal and multiphoton microscopes. The position helps develop programs for after sales installation, preventive maintenance, and service contracts to support a growing line of imaging systems. Field Service Engineer must have a solid understanding of the life science industry; laser, optics and microscopy experience is preferred.

A postdoctoral position at the University of Toronto is immediately available for exceptional candidates interested in applying single-molecule imaging to study the molecular and cellular mechanisms involved in the development of the fruit fly embryo. The position will be under the joint supervision of Dr. J. N. Milstein in the Department of Physics (https://www.utm.utoronto.ca/milsteinlab/) and Dr. R. Fernandez-Gonzalez at the Institute of Biomedical Engineering (https://www.quantmorph.ca/)

Qualifications:

• A keen interest in interdisciplinary research.
• Ph.D. in Physics, Chemistry/Biochemistry, Biomedical Engineering, Quantitative Biology, or related field.
• A track record of scientific productivity.
• Have strong verbal and written communication skills.
• The position is funded for a two-year period with an initial salary of $50k/year + benefits. Applicants should directly contact Dr. J. Milstein by email (josh.milstein@utoronto.ca). In your correspondence, please provide an up-to-date CV and contact information for three references.

The University of Toronto is strongly committed to diversity within its community and especially welcomes applications from racialized persons / persons of colour, women, Indigenous / Aboriginal People of North America, persons with disabilities, LGBTQ2S+ persons, and others who may contribute to the further diversification of ideas.

Job description

Identifyn™ LLC, a Sarasota, Florida-based Microscopy Research laboratory specializing in High and Super Resolution Microscopy serving both industry and academia, seeks a fluorescent imaging scientist to support our client needs in light microscopy applications, e.g., wide field, confocal, structured illumination, high-throughput, and super-resolution immunofluorescence.

Identifyn™ Core equipment includes but is not limited to Zeiss Apotome 3 Widefield SIM, Zeiss Elyra with Super Resolution SIM (grid and lattice) and PALM/STORM, Zeiss LSM900 with Airyscan, Vutara VXL STORM. We also have IF Multiplex from Bio-Techne (Jess). Command of Zen Blue and Black are essential. Identifyn™ processes data via our Acquifer HIVE built on a 10 GB internal network. General knowledge of computing large image files, 3D files, and super resolution files, moving them is a plus.

As a start-up in biotechnology, we seek to create an innovative company where our team can build on their personal expertise while experiencing a strong work/life balance. Identifyn™ provides a collaborative, inclusive culture of passionate people for advancing super-resolution applications throughout the many disciplines of scientific research. Our company's mission is to ensure unfettered access to all divisors of the research community, academia, and industry via our model of refined experimentation, fast-paced results, and affordable solutions to much-needed data, breaking down the barriers to this groundbreaking technology.

The ideal candidate will hold a Ph.D. in Molecular or Cell Biology, Biochemistry, Pharmacology, or other cellular-based fields while demonstrating a command of immunofluorescent applications and microscopy techniques. The candidate will work closely with our Chief Scientific Officer, who has expertise in super-resolution microscopy applications, to support our client's research goals across industry and academia.

· Experimental design and organize research projects · Development and optimization of immunofluorescent sample preparation and internal protocols · Image collection, quantification, and analysis · Data handling and reporting · Implement advanced techniques in immunofluorescence · Maintain and optimize microscope operations · Maintain and optimize the laboratory environment (equipment, reagents, cell culture, immunohistochemistry, and other sample support) · Work with our equipment providers to set up and maintain equipment and train Identifyn™ team members on equipment operation · Assist and provide value to our clients in all aspects of experimental design, sample preparation, image collection, and analysis throughout all Identifyn™ projects · Training and support of Identifyn™ lab technicians Minimum Qualifications · Doctoral Degree. Experience will not substitute in place of a degree. · The ability to effectively run high-resolution microscopy instrumentation, command of imaging software, and super-resolution experience is a plus. · Proficiency with microscopy sample preparation. · Cell culture and immunohistochemistry. · Publications in peer-reviewed journals. · Demonstrated team leadership. · Strong interpersonal communication skills are essential. · Excellent English language skills (both verbal and written) are required. · Ability to analyze, organize, and prioritize work under pressure while meeting deadlines in a fast-paced environment. · Ability to process and handle confidential information with discretion. · Ability to work evenings, nights, and weekends as necessary. · Ability to work independently or in a team environment. Job Type: Full-time

Salary: $100,000.00 - $135,000.00 per year

Benefits:

• Health insurance
• Paid time off Schedule:
• Monday to Friday Ability to commute/relocate:
• Sarasota, FL 34237: Reliably commute or planning to relocate before starting work (Required) Application Question(s):
• Experience with Zeiss Zen Blue or Black Education:
• Doctorate (Required) Work Location: In person

The Center for Biomedical Research Support (CBRS) is a collection of 10 service centers that operates under the Vice President for Research, Scholarship and Creative Endeavors and broadly supports the research community on campus and externally. CBRS serves a central role across all of campus to provide access to cutting-edge technology, expert advice, and centralized services. CBRS is comprised of core facilities including Biomedical Imaging, Bioinformatics, Biological Mass Spectrometry, Biomedical Research Computing, Cryo-EM imaging, Genome Sequencing, Microscopy/Flow Cytometry and Mouse Genetic Engineering. In addition, CBRS provides laboratory support in the forms of stockrooms, electronics repair, and external services drop boxes. The Deputy Executive Director serves the role of unifying operations and serving as a leader within CBRS as well as a connection to external offices and units outside of CBRS.

"Qualifications Required: A Ph.D. in a relevant field of Engineering or Biology or a related field and a demonstrated track record of productive research is required (1st author publications in established societal or field-leading journals).   Preferred: Candidates should be experienced in optical imaging. Experience with essential techniques of cell biology and multiphoton microscopy is desirable. Successful candidates will be able to independently design imaging experiments and analyze molecular to cell scale imaging data. Successful candidates will also have excellent communication and organizational skills, creative approaches to experimental design, and must be able to work collaboratively.     Principal Duties and Responsibilities: We have an opening for a research scientist (funded by multiple societal and NIH grants, including the University of Minnesota U54 Center for Multiparametric Imaging of Tumor Immune Microenvironments), available immediately in the Department of Biomedical Engineering and the Masonic Cancer Center at the University of Minnesota-Twin Cities. The objective of this team science work is perform advanced imaging experiments of archival samples (e.g. histology and immunohistochemistry or immunofluorescence slides) and live cells and tissues. The work will not fully center around a single project or grant, but a broader imaging base to support multiple projects and emerging collaborations. The successful candidate will use advanced optical imaging, primarily multiphoton excitation, second harmonic generation, and multiphoton fluorescence lifetime imaging microscopy, as well as more standard linear microscopies (such as confocal microscopy), to advance our understanding of cancer cell behaviors dynamics, particularly dynamics of key immune cell populations in solid tumors. The candidate will be responsible interacting and integrating with teams of graduate students, postdoctoral trainees, and research scientists in the Provenzano lab. The candidate will also be responsible for interfacing with collaborating laboratories and coordinating experiments. The candidate will also be responsible for analyzing data, helping preparae of manuscripts along with the PI, and presenting results to the PI and at local, regional, and national meetings.  

• Work in conjunction with faculty mentor who determines the research agenda. (5%)
• Design and carry out experiments and analyze data (75%)
• Prepare and present data to study investigators. (10%)
• Author, co-author, and otherwise collaborate on reports, conference papers and journal articles. (10%)"

"How to Apply: Applications must be submitted online: https://humanresources.umn.edu/content/find-job (Job Opening ID 348078). To be considered for the position, please click the ‘Apply’ button and follow the instructions. You will have the opportunity to complete an online application for the position and attach a cover letter and resume."

The Centre for Advanced Microscopy (CAM) is looking for an enthusiastic team player with extensive experience in a wide range of microanalytical techniques including WDS and EDS analysis. The successful candidate is a person with excellent interpersonal skills and the capacity to quickly develop productive, professional relationships with colleagues and clients. Highly developed organisational skills and effective self-management are key. The successful applicant will provide expertise in the operation of various microanalytical techniques available across a range of scanning electron microscopes, including those related to the JEOL JXA8530F electron probe microanalyser (EPMA). The Microanalytical Engineer will also provide (i) expert advice and training on relevant applications on the EPMA and other high-end FESEMs, including SEM imaging, quantitative EDS and EBSD to researchers and students from ANU as well as external university clients and industry users; (ii) training workshops for clients from various disciplines and (iii) laboratory and equipment management including performance management and basic maintenance of instrumentation. For further information about this position please contact, Associate Professor Melanie Rug, T: +61 2 6125 7649, E: melanie.rug@anu.edu.au

Ever wondered how chromatin looks in situ in "real" cells during development and in gametes? Interested in pushing boundaries of structural cell biology?

Then wait no longer and apply for a PhD position to work with our multidisciplinary team of developmental biologists, epigeneticists, physicists and cutting edge electron microscopy experts at the MRC London Institute of Medical Sciences and the Rosalind Franklin Institute to unravel mysteries of chromatin organisation underpinning life and development

The National Cancer Institute (NCI), National institutes of Health (NIH) is seeking a talented Computational Biologist to join the CCR High-Throughput Imaging Facility (HiTIF) as a Staff Scientist.

HiTIF is a shared collaborative resource for CCR and NIH Investigators. We work with laboratory scientists to design and execute novel high-throughput, fluorescence microscopy-based imaging assays, which are used to identify and dissect the molecular mechanisms underlying physiological and pathological cellular processes in functional genomics screens. We have a demonstrated successful record in developing cutting edge computational workflows to study biological pathways involved in genome architecture, chromatin regulation, the DNA damage response, cancer, and aging, among others. For more information visit our webpage.

HiTIF is expanding its data science capabilities to support the growing need for advanced single-cell analysis of images generated by NCI light microscopy cores. The Staff Scientist will work closely with multidisciplinary teams, collaborating with researchers, other computational biologists at HiTIF, and principal investigators, to derive biological insights from complex imaging datasets. The successful candidate will be proficient in fluorescence microscopy image analysis, and develop machine learning and deep learning models to analyze images and data.

The NIH is a vibrant research environment, and opportunities for professional growth and development. In this role, you will have an opportunity to work as part of a team to develop and implement novel computational approaches to dissect cellular function in healthy and diseased states using a variety of high-throughput imaging assays. Furthermore, you will contribute to cutting-edge research initiatives aimed at the understanding, diagnosis, and treatment of cancer.

For additional details about the position, and for instructions on how to apply. please visit the URL below.

Working Location: MASSACHUSETTS, WALTHAM (may allow for some remote work) Are you looking for a company that cares about people’s lives and health, including yours? At EVIDENT, we help make people’s lives healthier, safer and more fulfilling, every day.    Let’s inspire healthier lives, together.

Job Description

Evident Scientific is seeking a highly motivated and passionate problem solver to join the Life Science Research Microscopy Marketing team as Associate Product Manager. The successful candidate will be responsible for managing their optical microscopic/imaging systems product portfolio, developing, and executing global product strategies, and driving the growth for their microscope product lines.

Job Duties

* Primary function is to support sales activities through cross-functional coordination, imaging systems product demonstration (hands-on, hardware and software), promotion and training to ensure the success of their microscopic product lines.   *  Conduct market research to identify new product opportunities, customer needs and competitor landscape.   *  Plan new product launches with GTM strategy.   *  Analyze sales opportunities and customer profiles.   *  Propose product modifications/additions/improvements, develop and implement new product business plans.   *  Create marketing communications collateral such as applications articles, videos, and product bulletins to support sales activities, website content development and social media. Support and manage national or local trade shows as assigned.    * Serve as internal subject matter expert on microscopic hardware, software and imaging analysis, and manage the life cycle of product lines.   * Collaborate with cross-functional teams to ensure that their optical imaging solution products meet customer needs and are in compliance with regulatory requirements.

Job Requirements

  REQUIRED QUALIFICATIONS:   *  Bachelor’s degree in Physics, Biomedical Engineering, Neuroscience, Business Administration, Marketing or other scientific field required. Advanced degree holder preferred.   * Strong interpersonal and communication skills and the ability to work effectively with a wide range of constituencies in a diverse and global community are essential.   *  Must be a strong problem solver with a bias toward action – able to move quickly and decisively; has results-driven orientation.   *  Travel up to 30-50% expected.   *  Strong working knowledge of Optical Imaging Systems, Microsoft Office, Excel, and PowerPoint required.   PREFERRED QUALIFICATIONS: * Two or more years of Life Science product marketing or sales experience preferred. *  Experience with marketing communications preferred.   We realize work isn’t just a job to you.   It’s a big part of your life, but not the only part. That’s why we offer competitive salaries, a robust 401(k) program, annual bonus program and comprehensive medical benefits, as well as tuition reimbursement, flexible schedules, parental and adoption leave, on-site services and Colleague Affinity Networks — so you can be ready for where life can take you.   EVIDENT is passionate about the solutions it creates for the life sciences, and industrial equipment industries. For more than 100 years, Olympus has focused on making people’s lives healthier, safer and more fulfilling by helping detect, prevent, and treat disease, furthering scientific research, ensuring public safety, and capturing images of the world. Olympus has manufactured microscopes since the company’s founding in 1919. Today, EVIDENT is a leading manufacturer of optical and digital microscope systems for life science solutions. EVIDENT’s Life Sciences division supplies microscope systems for biological use in clinical, research, and educational applications. For more information, Click Here.   It is the policy of EVIDENT to extend equal employment and advancement opportunity to all applicants and employees without regard to race, color, national origin (including language use restrictions), citizenship status, religious creed (including dress and grooming practices), age, sex (including pregnancy, childbirth, breastfeeding, medical conditions related to pregnancy, childbirth and/or breastfeeding), gender, gender identity and expression, sexual orientation, marital status, disability (physical or mental) and/or a medical condition, genetic information, ancestry, veteran status or service in the uniformed services, and any other characteristic protected by applicable federal, state or local law.

EvidentLifeScience

Posting Notes: || United States (US) || Massachusetts (US-MA) || Waltham || 

We are actively seeking a highly skilled and passionate Microscopist to join our team at the HSC Cell Imaging Core, which is located at the University of Utah in Salt Lake City, Utah. As a service unit under the VPR office, the Core provides access to a wide range of advanced instruments, (>15) including fluorescence, confocal, spinning disk confocal, 2 photon, and STEDYCON microscopes, and slide scanners. In addition, the Core is expanding its capabilities with the upcoming integration of a Nikon Ring-TIRF spinning disk microscope and a NanoString system.

The successful candidate should possess a Ph.D. in a relevant field, such as biology, engineering, or physics, and must have excellent skills in advanced microscopy techniques, as well as experience in a service environment, including training and assisting researchers, and troubleshooting instrument issues. Click the link to apply: https://employment.utah.edu/salt-lake-city-ut/research-associate-microscopist/478DF09827BD4BF7B90ED80405E42DFB/job/ 

The Core understands that this is a unique multidisciplinary position and provides complementary training to ensure the successful candidate is able to effectively integrate into the team. While prior experience with scientific imaging analysis tools, such as Imaris, Nikon Elements, and ImageJ, is preferred, it is not a strict requirement. Strong communication and interpersonal skills are essential for success in this dynamic and multidisciplinary role.

Please reach out for any questions.

As an independent research organization, the Morgridge Institute for Research explores uncharted scientific territory to discover tomorrow’s cures. In affiliation with the University of Wisconsin-Madison, we support researchers who take a fearless approach to advancing human health in emerging fields such as regenerative biology, metabolism, virology and biomedical imaging. Through public programming, we work to inspire scientific curiosity in everyday life.

The Opportunity:

Applications are invited for a Postdoctoral Research Associate role at the Morgridge Institute for Research in collaboration with the University of Wisconsin, Madison. The objective of this research is to develop and apply optical microscopy and analysis techniques to quantitatively monitor metabolic and structural changes in cancer, stem, and immune cells. Measurements will be made in mouse models of cancer in vivo, patient immune cells, and patient tumors maintained in 3D cultures (“organoids”). The Postdoctoral Research Associate will work with multiphoton and fluorescence lifetime imaging microscopy in collaboration with engineers, clinicians, and biologists. The applicant will have access to state-of-the-art resources in biomedical photonics, and opportunities to develop other photonics techniques including high-throughput microscopy and flow cytometry. This position will also provide a unique opportunity to gain experience in a multidisciplinary research environment.

Duties Include:

• Perform imaging experiments and quantitative image analysis.
• Maintain cell and organoid cultures.
• Conduct animal procedures.
• Maintain the cell culture lab, lab equipment, and organize lab inventory.
• Keep up to date with training per safety and protocol requirements.
• Clearly communicate research progress results to project stakeholders
• Prepare weekly overviews of work completed and planned. Give updates, including outlining progress and setbacks, and solicit feedback in regular meetings.
• Conduct data analysis and prepare data for presentation and submission in peer-reviewed journals and at professional meetings
• Contribute ideas and feedback to other researcher’s projects in regular meetings.
• Assist or lead other projects within the laboratory as appropriate.
• Form and contribute to collaborations with other labs. Maintain relationships with collaborators and hold oneself to professional standards.
• Other miscellaneous duties as required

  Requirements:

  To perform this job successfully, an individual must be able to perform each primary duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations will be considered and may be made to enable individuals with disabilities to perform the primary responsibilities.

  Education and Experience

• Ph.D. degree in an appropriate field of engineering, the physical sciences, or biology (with quantitative expertise).
• Previous experience in fluorescence microscopy and/or cell culture or small animal studies is particularly helpful.

  Knowledge, Skills and Abilities Required:

• Experience in programming, e.g. MatLab, Python, R, micromanager, C, C++, Labview.
• Experience in cell culture.
• Strong background in biology and engineering.
• Ability to perform reproducible quantitative imaging experiments.
• Working knowledge of quantitative analysis.
• Ability to leverage previous experiences to learn and develop new skills.
• Ability to take initiative and independently evaluate project options.
• Ability to handle multiple assignments concurrently while working independently and effectively under deadlines.
• Ability to work both independently and as part of a dynamic research team.
• Excellent attention to detail.
• Strong written and oral communication skills.
• Strong organization skills and attention to detail.

In order to insure the safety of our workplace, proof of COVID-19 vaccination is required unless an exemption is granted for medical, disability or religious reasons.

Interested candidates should submit a curriculum vita, a list of three references and a one-page statement of research interests via the link provided.

We are recruiting a new director for the Biological Imaging Development CoLab (BIDC) at the University of California in San Francisco.

CoLabs (http://colabs.ucsf.edu/) is a new model for supporting collaborative research at UCSF. The BIDC is one of five CoLabs teams with specialized research and technical expertise in analyzing biological samples using various approaches. These teams work together closely and collaborate with a large group of investigators in many UCSF departments. BIDC’s missions include microscopy education, training, consulting, and technical support and microscopy research and development.

The BIDC Director role is multifaceted and requires independence, initiative, organization, and flexibility. The incumbent must have experience in biological-related microscopy research, strong interpersonal skills to work closely with investigators, students, postdoctoral fellows, visiting scholars, and staff members, and strong time management skills. The incumbent also must have strong mentoring and leadership skills.

In general, the BIDC Director’s activities will include, but are not limited to: maintenance and management of the Biological Imaging Development CoLab’s (BIDC) microscopes and support equipment; training and assisting new users on microscopes, techniques, and data analysis; assisting in experimental design and analysis pipelines; direct supervision of two or more employees; oversight of CoLab’s budget including salaries and materials; coordinating team members for new initiatives and projects; and the mentoring and career development of co-workers. The BIDC Director is also responsible for keeping the facility current with trends and needs of the microscopy community. This is accomplished either through the raising funds and purchasing commercial equipment, designing and developing technology, or adding new support resources for the research community. The incumbent will report directly to the Director of the CoLabs and the BIDC Steering Committee.

Required qualifications:

A PhD in natural sciences; biology, chemistry, physics, or related discipline. At least 5 years of experience in microscopy-based instrument development. At least 5 years of experience in high-dimensional microscopy data analysis. At least 5 years of experience in biology specific microscopy techniques and analysis. Proficiency in microscopy data analysis using available software such as Imaris, Elements, LAS, FIJI, ImageJ, and Ilastik. Demonstrated skills and experience in teaching and mentoring graduate students and professional trainees. Strong interpersonal skills and the ability to work with individuals from diverse backgrounds. Strong time management skills and demonstrated attention to details. Preferred qualifications:

Excellent written and verbal communication including writing of research manuscripts, and scientific oral presentations (in-person and virtually). Experience in preparing grant proposals, especially shared equipment grant proposals. Experience in management of a shared research resource or core facility. Proficiency in custom microscopy data analysis using Matlab and Python. Hands-on experience in confocal, widefield, light-sheet, and super-resolution microscopy techniques. Experience in computer assisted drawing (CAD) for instrument design and development. Experience in electrical circuit design with soldering skills.

The Digital Pathology Scientist is responsible for developing digital pathology methodologies, techniques, workflows, and supporting processes to help execute a number of commercial and research priorities related to CND's patient-focused mission. As a key member of the R&D team and co-leader of the Company's Digital Pathology Initiative, the Digital Pathology Scientist will drive ongoing AI-driven methods to analyze and characterize pathologic images of neurocutaneous biomarkers generated through CND's innovative skin-based diagnostic tests. The Digital Pathology Scientist will play an instrumental role in: (1) creating and executing digital prereading capabilities and efficient workflows for CND's commercial testing business, (2) ongoing R&D projects related to analysis of neurocutaneous biomarkers associated with specific neurologic disorders including synucleinopathies and long COVID pathologies, and (3) specific projects with CND biopharma clients developing drugs targeting alpha-synuclein. In collaboration with pathologists and R&D scientists, the Digital Pathology Scientist will also design, develop, validate, and implement quantitative image analysis/artificial intelligence solutions and algorithms for digital interpretation of immunofluorescence slides for current and emerging neurodiagnostic biomarkers. The Digital Pathology Scientist will become proficient at using CND's current and future suite of digital pathology equipment, software, and other technologies.

We are recruiting a European Application Specialist for Nikon Europe BV Healthcare Division (NEBV-HC). In this position, you will support the sales & training of Nikon’s high-end microscope systems product portfolio in Europe. We are looking for someone who will have an outstanding understanding of Nikon’s products and their application to customer needs and how this fits into the overall microscopy market and trends. You will be working in the European Applications & Support team and work closely with other HQ teams including Product Management, Marketing Communications & Service. You will support branch and distributor colleagues.

We are recruiting a European Support Specialist for Nikon Europe BV Healthcare Division (NEBV-HC). In this position, you will provide remote support to Nikon branches and distributors for product and support related questions including technical information, compatibility information and diagnosis of problems. We are looking for someone who will have an outstanding understanding of Nikon’s products and their application to customer needs and how this fits into the overall microscopy market and trends. You will be working in the European Applications & Support team and work closely with other HQ teams including Product Management, Marketing Communications & Service. You will support branch and distributor colleagues.

The Cleveland Clinic Florida Research and Innovation Center (FRIC) is seeking a motivated and skilled microscopist to manage and direct its Light Microscopy Core. This position requires advanced technical and scientific expertise in imaging acquisition and analysis, along with the ability to work collaboratively in a BSL-2/3 research facility. The Light Microscopy Core Director will report to the Director of Research Compliance and Operations.

Responsibilities: * Manage the daily operations of the Core, including oversight of Core projects and infrastructure; the purchase, utilization, and upkeep of equipment; and hiring and managing of junior Core staff * Train FRIC investigators in the proper use of microscopes and imaging equipment; troubleshoot experimental and technical problems to help optimize techniques and improve understanding of biological questions * Provide advice to clients on experimental design, protocols, and sample preparation * Provide post-acquisition image processing and analysis and assist with interpretation of data * Together with the Director of Research Compliance and Operations, establish and implement the Core's business plan, policies, and procedures, while assessing needs and opportunities for improvement and innovation * Maintain SOPs and quality control measures in order to monitor compliance of the Core, its Staff, and users with institutional and regulatory policies in a BSL-3 environment (e.g., biohazard material handling, IBC protocols, and IACUC protocols) * Participate in grant and manuscript writing * Help develop informational and educational materials to communicate information to Core users and help maintain the Core website * Supervise Core accounting; manage billing; maintain and generate reports, records and statistics; provide budgetary analyses as requested by the Director of Research Compliance and Operations.

Full job description here: https://www.lerner.ccf.org/florida/careers/

Any interested applicants should send a CV and resume to FRIC Director of Research Compliance and Operations, Sara Tavakoli at tavakos@ccf.org<mailto:tavakos@ccf.org>

Develop concepts/simulations/prototypes for computational light microscopy imaging applications in a world-leading research center.

The Director of the Center for Advanced Light Microscopy (CALM) will lead a team that provides access to state-of-art microscopes for use by the UCSF community and serves over 400 scientists a year. The candidate is expected to have a strong background in microscopy and image analysis. Strong technical knowledge, interpersonal skills, and a commitment to customer service is extremely important. Responsibilities:

• Administration of the imaging center including managing recharge proposals, billing, website maintenance, and grant writing
• Plan and execute acquisition of new equipment and upgrades to current microscopes
• Perform routine maintenance and repairs on core microscopes
• Assist researchers with image acquisition, image analysis, and experimental design
• Teaching microscopy theory and methods in workshops and graduate level courses Required Qualifications:
• A PhD degree in biology, physics, optics, or a related field.
• Candidates should have strong organizational skills, be flexible, and be able to prioritize tasks, have excellent verbal and written communication skills.
• Previous experience with microscopy, we are particularly looking for candidates with experience in multiphoton microscopy, programming, or development of microscopy hardware. Preferred Qualifications:
• Previous experience with equipment maintenance, image analysis, and training in a core facility environment is desirable.
• Experience working within collaborative, multidisciplinary teams.
• Experience in PC maintenance and Linux System administration. For positions that are 51% effort or more: The posted UC salary scales set the minimum pay determined by rank and step at appointment. See Table 5: https://www.ucop.edu/academic-personnel-programs/_files/2022-23/oct-2022-salary-scales/t5-summary.pdf. The minimum base salary range for this position is $106,900-$284,100. This position includes membership in the health sciences compensation plan (https://ucop.edu/academic-personnel-programs/_files/apm/apm-670.pdf) which provides for eligibility for additional compensation. For positions that are 50% effort or less: See Table 2 (https://www.ucop.edu/academic-personnel-programs/_files/2022-23/oct-2022-salary-scales/t2.pdf) for the salary range for this position. A reasonable estimate for this position is $82,200-$218,500. Please apply online at https://aprecruit.ucsf.edu/JPF04464 with cover letter, CV, statement of contributions to diversity, and contact information for three references. Applicant materials must list current and/or pending qualifications upon submission. The selected candidate must meet all of the qualifications at the time of appointment.

  APPLICATION REQUIREMENTS

  Document requirements

• Cover Letter
• Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).
• Statement of Contributions to Diversity - Please see the following page for more details: Contributions to Diversity Statement
• Statement of Research (Optional)
• Statement of Teaching (Optional)
• Misc / Additional (Optional) Reference requirements
• 3 required (contact information only)

  CAMPUS INFORMATION

  As a condition of employment, you will be required to comply with the University of California SARS-CoV-2 (COVID-19) Vaccination Program Policy found here: https://policy.ucop.edu/doc/5000695/SARS-CoV-2_Covid-19. UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.