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Brazilian Center for Research in Energy and Materials
Specialist in Advanced Methodologies in Biology - Bioimaging
Campinas, S√£o Paulo - Brazil
Latin America
Learn More
Deadline: Jun 28, 2024

The Specialist will be part of the Advanced Methodologies in Biology team, performing activities in the field of bioimaging, which include preparing biological samples, data collection, and image processing. The role also involves active participation in the routine of the Biological Imaging Laboratory (LIB), directly assisting users, providing necessary support and training, as well as analyzing and scheduling proposals. The Specialist will contribute to the development of laboratory documents, such as Standard Operating Procedures (SOPs) and scientific reports. They will work in a multidisciplinary team, interacting regularly with other areas of LNBIO, such as Operations and Maintenance. Requirements:

  • Bachelor's degree in Biology, Pharmacy, Chemistry, or related fields;
  • Master's degree in Biology or related fields;
  • Intermediate level of English;
  • Knowledge of biological sample preparation for microscopy, data collection in optical microscopy (preferably confocal and STED), data visualization, and processing;
  • Desirable experience in electron microscopy of biological samples;
  • Experience in user support is a plus.
University of Manchester
Research Associate in Multiscale Imaging
Manchester, UK
Europe
Learn More
Deadline: Jul 19, 2024

Applications are invited for a Research Associate to work with investigators at the Discovery Research Platform for Cell-Matrix Biology in Multiscale Imaging. The extracellular matrix is a complex network of fibrillar proteins, glycoproteins and secreted factors that form complex assemblies essential for tissue structure and function. Most components of the extracellular matrix are large, insoluble multicomponent complexes which are extensively post-translationally modified. Within the Manchester Cell Matrix Centre, we have expertise in imaging all hierarchies of matrix, from high resolution structures of individual matrix proteins to tissue-level imaging. One of our research themes is to now integrate these imaging approaches to visualise matrix across scales. Therefore, the aim of this project is to integrate the imaging from the molecular to the tissue scale. Working with research groups across the Platform and with Facilities (Electron Microscopy, Bioimaging, eBiC and National X-ray Computed Tomography), you will develop 3D imaging approaches (eg cryo-electron tomography of adhesion complexes and correlated microCT and SBF-SEM of tissues) which will be applied to matrix samples, and to integrate these data from different length scales.

EMBL
AMBER Postdoctoral Fellowship: A novel optical microscopy platform for cross scale imaging of mammalian and human fertility
Heidelberg, Germany
Europe
Learn More
Deadline: Sep 6, 2024

This postdoctoral position is part of the EU cofund research project AMBER, Advanced Multiscale Biological imaging using European Research infrastructures, will address scientific and sectoral gaps in biological imaging ranging from molecular, through cellular, to tissue, organ and organism levels of organisation, and is coordinated by LINXS Institute of advanced Neutron and X-ray Science. AMBER is funded by the EU Marie SkŇāodowska-Curie (MSCA) COFUND scheme. Your work may include clinical and biomedical projects. It may also include technique development work aimed at combining imaging techniques and data analysis to provide a more integrated picture of life processes in the context of health and disease. To be a postdoc fellow at the AMBER programme you will get unprecedented medical, biological, and methodological capabilities, with a profound potential impact for Europe‚Äôs next generation of research and researchers. When you have completed the AMBER programme you will be extraordinarily well equipped to further your career in academia, at infrastructures, in the health and MedTech sectors, and beyond.

EMBL
Scientist in Electron Microscopy Facility
Heidelberg, Germany
Europe
Learn More
Deadline: Jul 26, 2024

We are currently looking for a Research technician / Scientific Officer to join the EMCF. The position will involve direct participation in the research projects by performing ultrastructural analysis on a variety of biological specimens, by training users on the EMCF workflows and by contributing to the general organisation of the facility.

Cryo-EM Unit (National Facility for Structural Biology) at Human Technopole
EM Specialist
Milano, Italy
Europe
Learn More
Deadline: Jul 5, 2024

EM Specialist (Volume EM Applications: from fixation, HPF, AFS, sectioning all down to imaging) position More info about the position and the Unit here:   https://careers.humantechnopole.it/o/electron-microscopy-em-specialist-1   APPLICATION CLOSING DATE: July 5th, 2024   Number of positions offered: 1 Contract offered: CCNL Chimico Farmaceutico, Fixed-term 3 years with possibility of renewal - Employee Level Salary range: up to 40K, depending on the seniority of the candidate. Tax benefits where applicable.

Carl Zeiss AG
Internship/Master Thesis in deep learning-based methods for microscopy
Oberkochen, Germany
Europe
Learn More
Deadline: Aug 17, 2024

We seek a motivated and talented intern or Master's thesis student to work on a research project focused on exploring the potential of deep learning-based methods for microscopy. The successful candidate will have the opportunity to implement and evaluate DL-based methods and collaborate with a team of experts in the field. This is a unique chance to gain hands-on experience in cutting-edge research and contribute to the development of advanced microscopy techniques.

Your role:

  • Familiarize yourself with state-of-the-art deep learning-based methods for microscopy
  • Implement DL-based and analytical methods for microscopy
  • Evaluate methods with benchmark datasets
  • Possibly conduct real-data validation
  • Collaborate with the team to achieve project goals and deliverables
  • Communicate project progress and results to mentors and team members
  • Document the study results

Your profile:

  • Master's degree student in computer science, bio-engineering or related fields
  • Strong background in machine learning or related fields
  • Experience with deep learning frameworks (e.g., TensorFlow, PyTorch)
  • Experience with image processing (OpenCV, Open3D)
  • Familiarity with microscopy is a plus
  • Excellent problem-solving skills
  • Detail-oriented and able to work in a team
  • Self-motivated and independent working style with a passion for exploring complex and innovative topics
  • Good written and oral communication skills in English
  • Motivated, curious, and eager to learn
  • Available to work for at least six months (internship or Master's thesis)
Zeiss Group
Computational Imaging Scientist (f/m/x)
Oberkochen, Germany
Europe
Learn More
Deadline: Jul 17, 2024

You have ideas to shape the future of imaging and optical metrology? Research at ZEISS does shape the future - We believe that algorithms and hardware belong together and by co-designing them on equal footing we add value for our customers and push the boundaries of what is possible in imaging and optical metrology. Working on projects in the interface between algorithms, optic design, and system engineering you will develop visions and prototypes for future ZEISS products. Today these include light, electron, and X-ray microscopes as well as OCT devices, industrial CT scanners, and 3D measurement systems. You will bring your algorithmic knowhow and leverage the latest algorithm and technology advancements to generate ideas on how to address tomorrow’s challenges and upcoming megatrends. And you will use your expertise in algorithm design and implementation/prototyping skill to convince decision makers to change the development roadmaps for new ZEISS products.

UT Southwestern Medical School
Senior Research Scientist/Electron Microscopy
Dallas, Texas
USA

Apply online and send CV directly to Natalia.Gunko@UTSouthwestern.edu.

The successful candidate should hold a PhD or M.Sc. degree and have strong training in biological sciences or related field. It is also critical that the candidate has a history of working with electron microscopes. It is essential that the candidate possesses a deep understanding and experience in biological science electron microscopy and sample preparation. Experience in CLEM and/or volume electron microscopy is desirable. The ideal candidate should be technologically adept, a team player with strong interpersonal and communication skills, as well as being well-organized, structured, and capable of planning and executing tasks effectively. This position is available within the Department of Cell Biology at the Electron Microscopy Core Facility (EMCF). The EMCF offers transmission and scanning electron microscopy services, along with additional offerings such as correlative light and electron microscopy (CLEM), and immunogold labeling. The candidate will work close  ly with the Director, group members, and will play an important role in CLEM projects and Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) technology for large volume imaging of biological samples.

ESSENTIAL JOB FUNCTIONS: Collaborate with EMCF staff in day-to-day operations. Provide support to users for experimental design, sectioning, staining, and image acquisition. Perform sectioning and operate electron microscopes. Implement and adjust EM applications and workflows. Oversee user operations to ensure safe and effective instrument usage, and adherence to best-practice microscopy techniques.

REQUIREMENTS: Ph.D. or M.Sc. degree in Biological Sciences or related field, with 9 or more years of relevant experience in a multi-user electron microscopy-based facility or research laboratory. Proficiency in operating scanning and transmission electron microscopes, along with experience in biological science electron microscopy. Ability to support and engage with a diverse user base with varying levels of microscopy experience and skills. Strong interpersonal skills, capable of interacting with individuals at all levels including undergraduate students, graduate students, post-docs, staff, faculty, and industry customers. Willingness to learn and adapt to new techniques and technologies. Team-oriented work ethic. Kate Luby-Phelps, Ph.D.

University of Texas at Austin
Light Microscopy Specialist
Austin, Texas
USA
Learn More
Deadline: Jul 1, 2024

Job Details: The Center for Biomedical Research Support (CBRS) is a collection of 10 service centers that operates under the Vice President for Research, Scholarship and Creative Endeavors (OVPR) and broadly supports the research community on campus and externally. CBRS serves a central role across all of campus to provide access to cutting-edge technology, expert advice, and centralized services. CBRS is comprised of core facilities including Biomedical Imaging, Bioinformatics, Biological Mass Spectrometry, Biomedical Research Computing, Cryo-EM imaging, Genome Sequencing, Microscopy/Flow Cytometry and Mouse Genetic Engineering. In addition, CBRS provides laboratory support in stockrooms, electronics repair, and external services drop boxes. The Microscopy and Imaging Facility (MIF) is a core facility in the Center for Biomedical Research Support.  Our mission is to support multidisciplinary research and further scientific knowledge by providing access to state-of-the-art light microscopy, flow cytometry, and other research instrumentation; consultations with our expert staff; instrument trainings; and educational seminars and workshops. We are seeking a skilled and motivated Light Microscopy Specialist to join our team. In this role, you will be responsible for training and experimental support for fluorescence microscopes, particularly confocal microscopes.  As a member of our team, you will play a critical role in advancing research projects at UT. We provide excellent customer service to our researchers, and we believe in making our instrumentation accessible to any researcher, no matter their previous experience level or knowledge. By training researchers in this role, you will contribute to the development of the next generation of scientists.  Through working in a multidisciplinary core facility, you will gain experience with a wide variety of sample types and experiments. We are looking for someone who can work full-time on-site in the Microscopy and Imaging Facility to provide instrument support when needed. UT Austin offers a competitive benefits package that includes:  

  • 100% employer-paid basic medical coverage¬†¬†
  • Retirement contributions
  • Paid vacation and sick time
  • Paid holidays Please visit our Human Resources (HR) website to learn more about the total benefits offered.

    Purpose

    This position will support research at the University of Texas at Austin by providing training on advanced fluorescence microscopes and consultations with users on their experiments. 

    Responsibilities

  • Trains researchers on the theory behind advanced fluorescence microscopes and on how to acquire quantifiable light microscopy data.¬†¬†Instructs researchers on proper operation and ensures safe, responsible use of microscopes. Provides additional support for troubleshooting and new microscopy techniques after training.
  • Advises researchers about experiment design, data acquisition, and image analysis. Responds to researcher inquiries in a timely manner during working hours.
  • Stays current with advances in light microscopy instrumentation and techniques.¬†¬†Works with the facility director to identify upgrades to our instrumentation.
  • Provides periodic maintenance of current and future instrumentation and related computer systems in the Microscopy and Imaging Facility.¬†¬†Monitors use of microscope rooms and ensures spaces are kept tidy.¬†¬†Performs routine quality control of advanced fluorescence microscopes and document results.¬†¬†Consults with the facility director to diagnose microscope issues.¬†¬†Schedule with external service technicians as needed.
  • Operates microscopes on behalf of researchers as assisted use.
  • Develops operating and safety protocols as required for current equipment and changes in methodology.¬†¬†Assists the facility director with adherence to laser safety requirements.
  • Conducts lab administrative duties, including imaging supplies management and monthly billing.¬†¬†Maintains record keeping and scheduling for microscopy instrumentation.
  • Other related functions as assigned.

    Required Qualifications

  • Bachelor's degree with 4 years' experience or master's degree with 2 years' experience in life science, engineering, or another related field
  • Hands-on experience with a laser scanning confocal microscope
  • A working knowledge of the fundamentals of confocal microscopy and other fluorescence microscopy techniques
  • A working knowledge of fluorescence microscopy sample preparation techniques and best practices
  • Experience teaching and/or training others to use scientific instruments
  • Ability to work independently to complete responsibilities
  • Strong organizational and time management skills
  • Strong interpersonal skills to work in a customer-facing role
  • Demonstrated ability to work successfully in a team environment
  • Excellent verbal and written communication skills Relevant education and experience may be substituted as appropriate.

    Preferred Qualifications

  • PhD in life science, engineering, or another related field
  • Hands-on experience using other advanced fluorescence microscopes, such as PALM/STORM, SIM, spinning disk, TIRF, multiphoton, STED, or selective plane illumination light sheet
  • Experience with microscopy sample preparation protocols, including clearing
  • Experience with image processing and analysis with ImageJ, Imaris, NIS-Elements, MATLAB or other software
  • Experience with microscope maintenance, including cleaning, alignment, and quality control
  • Prior professional experience in a core facility

    Salary Range

    $65,000 + depending on qualifications 

    Working Conditions

  • Uniforms and/or personal protection equipment (furnished)
  • May work around chemical fumes
  • May work around standard office conditions
  • May work around biohazards
  • May work around chemicals
  • Repetitive use of a keyboard at a workstation
  • Use of manual dexterity
  • Lifting and moving

    Required Materials

    Please mark "yes" on the application for required materials. Failure to attach all additional materials listed may affect candidates being considered for the position.

  • Resume/CV
  • 3 work references with their contact information; at least one reference should be from a supervisor
  • Letter of interest Important¬†for applicants who are NOT current university employees or contingent workers:¬†You will be prompted to submit your resume the first time you apply, then you will be provided an option to upload a new Resume for subsequent applications. Any additional Required Materials (letter of interest, references, etc.) will be uploaded in the Application Questions section; you will be able to multi-select additional files. Before submitting your online job application, ensure that¬†ALL¬†Required Materials have been uploaded. ¬†Once your job application has been submitted, you cannot make changes.

    Employment Eligibility: Regular staff who have been employed in their current position for the last six continuous months are eligible for openings being recruited for through University-Wide or Open Recruiting, to include both promotional opportunities and lateral transfers. Staff who are promotion/transfer eligible may apply for positions without supervisor approval.

    Retirement Plan Eligibility: The retirement plan for this position is Teacher Retirement System of Texas (TRS), subject to the position being at least 20 hours per week and at least 135 days in length.

    Background Checks: A criminal history background check will be required for finalist(s) under consideration for this position.

    Equal Opportunity Employer: The University of Texas at Austin, as an equal opportunity/affirmative action employer, complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. The University is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender expression, disability, religion, or veteran status in employment, educational programs and activities, and admissions.

    Pay Transparency: The University of Texas at Austin will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information.

    Employment Eligibility Verification: If hired, you will be required to complete the federal Employment Eligibility Verification I-9 form.  You will be required to present acceptable and original documents to prove your identity and authorization to work in the United States.  Documents need to be presented no later than the third day of employment.  Failure to do so will result in loss of employment at the university.

    E-Verify: The University of Texas at Austin use E-Verify to check the work authorization of all new hires effective May 2015. The university’s company ID number for purposes of E-Verify is 854197. For more information about E-Verify, please see the following:

  • E-Verify Poster (English) [PDF]
  • E-Verify Poster (Spanish) [PDF]
  • Right To Work Poster (English) [PDF]
  • Right To Work Poster (Spanish) [PDF]

    Compliance: Employees may be required to report violations of law under Title IX and the Jeanne Clery Disclosure of Campus Security Policy and Crime Statistics Act (Clery Act). If this position is identified a Campus Security Authority (Clery Act), you will be notified and provided resources for reporting. Responsible employees under Title IX are defined and outlined in HOP-3031. The Clery Act requires all prospective employees be notified of the availability of the Annual Security and Fire Safety report. You may access the most recent report here or obtain a copy at University Compliance Services, 1616 Guadalupe Street, UTA 2.206, Austin, Texas 78701.

UT Southwestern Medical School
Electron Microscopy Technician
Dallas, Texas
USA
The UT Southwestern Electron Microscopy Core Facility (EMCF) is looking for an entry level technician to join our staff. The EMCF provides electron microscopy services to the research community at UT Southwestern in Dallas.  The new hire will help with processing and sectioning customer samples, as well as operating the three electron microscopes in the core. 

Interested people must apply online: https://jobs.utsouthwestern.edu/job/20415506/electron-microscopy-technician-cell-biology/. 

Please also send a resume directly to Dr. Natalia Gunko: natalia.gunko@utsouthwestern.edu.
McGill University
BioImaging North America (BINA) Community Congress Microimpact Study
Montreal, Quebec
Canada

Project Summary The main objective of this project is to understand the barriers limiting interactions between two communities of practice in the life sciences: cutting-edge microscope builders/software programmers versus expert microscopy users. We will use and adapt for research professionals the microimpact taxonomy that was developed by the team of the Humanomics Research Centre at Aalborg University in Copehagen, Denmark1. A pilot study will be performed at the occasion of the BioImaging North America Community Congress in September 2024. This study will help develop methods to monitor and analyze participants interactions to understand the dynamics of collaboration (or lack thereof). Job Description We are seeking an enthusiastic intern to join our research team for an exciting project in the field of social sciences applied to the international bioimaging community. This internship offers a blend of full-time and part-time work, with the unique opportunity to contribute to a high-impact multidisciplinary research project that spans over several months.

See Link for more details!

Institute of Science and Technology Austria (ISTA)
Microscopy & Cytometry Technician
Klosterneuburg near Vienna, Austria
Europe
  • Full Time (40 h/w)
  • Klosterneuburg near Vienna, Austria
  • ‚ā¨ 2,850* gross/month (basis full-time 40 hours/week)

Your Responsibilities

The Imaging & Optics Facility (IOF) provides 'state of the art' Microscopy Application and Flow Cytometry services, as well as assistance in image analysis and custom optical development solutions. We aim to strengthen our international team with a highly motivated and reliable team player.

  • Support in general core facility service and infrastructure tasks, including: ordering, inventory, routine facility checks and control of facility (loan) equipment, organization of calibration standards and optical maintenance tools
  • Provide basic training & operating assistance for microscopy and/or cytometry equipment and services
  • Performing routine maintenance, quality monitoring and system performance checks
  • Functioning as building representative for the IOF to coordinate communication and activities with other units & divisions
  • Contribute to event-organization, such as: system demonstrations, annual microscopy-course, technical work-shops, user trainings and outreach events
  • Provide support in the areas of basic image/data analysis (on user-demand) and laser safety, if required

Your Profile

  • BA or MSc in Life Science/(bio-)physics or equivalent
  • Relevant work experience, ideally in a core facility and/or academic environment
  • Service oriented work style
  • Ability to work independently and as part of the team
  • Structured, precise and reliable working style and high degree of organizational skills
  • Excellent communication skills in English

Your benefits

  • Education & training
  • Multiple health offers
  • Free shuttle bus
  • Pension insurance
  • Childcare
  • Cafeteria

ISTA is growing. Grow with us!

Institute of Science and Technology Austria (ISTA) is a constantly growing international institute for conducting frontier research in mathematics, computer science, life sciences & physical sciences. We strive to recruit passionate professionals from across the world over all fields who strive to support our goal of excellent research. Located within a beautiful campus on the outskirts of Vienna, we offer multiple opportunities for personal growth in a stable working environment. Get an insight! ISTA promotes a diverse and inclusive working environment and is committed to the principle of equal employment opportunity for all applicants, free of discrimination. All employment decisions at ISTA are based on job requirements, qualifications, merit and organizational needs. We strongly encourage individuals from underrepresented groups to apply.

Please apply via our job portal. 

*This position comes with possible overpayment depending on education, qualification and work experience. For more information on how ISTA processes your personal data, please refer to www.ista.ac.at/data-protection.

United Therapeutics
Research Associate I/II - Tissue Imaging
Durham, North Carolina
USA

Support development of bioengineered lung tissue using a variety of imaging and analysis techniques including immunostaining, tissue clearing, and confocal imaging. See the job posting for a more detailed description of responsibilities.

Laboratoire Kastler Brossel
High-speed computational Raman imaging of bacteria
Paris, France
Europe
Learn More
Deadline: Sep 30, 2024

Background. Raman microscopy is a label-free chemically-selective technique with superb spatial resolution. Even though technological developments in Raman microscopy are impressive in terms of speed [1], there is still the issue of overwhelmingly large data sets generated, an aspect that fundamentally precludes video-rate microspectroscopy. In recent years, we developed a set of new computational microscopy tools exploiting paradigm shifts in signal processing (Compressive Sensing) in order to achieve chemically selective imaging at high speeds. We coin this set of methods compressive Raman microspectroscopy [2]: we design an experiment which retrieves the same outcome as in traditional Raman imaging, however performing considerably fewer measurements. For that purpose, we develop novel spectrometers layout using fast digital micromirror devices (DMD). Exploiting this emerging technology, we have shown record acquisition speeds and sensitivity in various biomedical systems. Recent outcomes allowed us to reach video-rate speeds for imaging in spontaneous Raman imaging [3].

As a next step, we will further increase the acquisition speed to tackle motile biological systems. In particular, we aim at imaging biofilm formation in bacteria biofilms. The successful applicant will work on a new spectrometer layout, in order to increase the dynamic range for imaging species at low and high concentration levels with compressive Raman imaging. This would allow to observe the formation of bacterial biofilms [4] in real time.

Candidates profile. Various PhD/Post-doc positions are open. Regardless of the position applied, the candidate must be ambitious and highly motivated, have a particular taste for optics and interdisciplinary research. Regarding the PhD position, he/she should have a degree in Physics or closely related area. Regarding the Post-Doc position, he/she should have a PhD in Physics, Physical Chemistry, or closely related area (e.g. Signal Processing, Materials Science), be highly independent (both at the organizational and scientific level) and aspiring supervisor. Programming skills are compulsory. Candidates from Life Sciences are also encouraged to apply. Previous experience with Raman spectroscopy is a plus.

Offer details. The Post-Doc is for 2-year contract (with possibility of renewal). The PhD position is for 3 years. Both positions include all social benefits in France (health care, pension system, unemployment aid etc.). Post-doc gross salary will vary depending on the experience. The position is to start as soon as possible, but will stay open until suitable candidates are found.

How to apply. These positions are part of the activities of the Complex Media Optics Lab, at the Laboratoire Kastler-Brossel, ENS, Paris. Applicants interested within these research activities should submit CV, a brief motivation statement, and at least one contact detail for requesting a recommendation letter, to the point of contact: Hilton Barbosa de Aguiar, h.aguiar@lkb.ens.fr .

References [1] J.-X. Cheng and X. S. Xie, Science 350(6264), (2015) [2] P. Berto et al, Opt. Lett. 42(9), 1696 (2017); C. Scott√© et al, Anal. Chem. 90(12), 7197‚Äď7203 (2018); F. Soldevila et al, Optica 6(3), 341 (2019); B. Sturm et al, ACS Photonics 6(6), 1409‚Äď1415 (2019) [3] Gentner et al, arXiv:2301.07709 [4] P. Thomen et al, Soft Matter 16(2), 494‚Äď504 (2020); P. Thomen et al, PLoS One 12(4), e0175197 (2017)

University of Texas at Austin
Core Facilities Technician, Center for Biomedical Research Support
Austin, Texas
USA

Job Posting Title: Core Facilities Technician, Center for Biomedical Research Support

Hiring Department: Center for Biomedical Research Support

Position Open To: All Applicants

Weekly Scheduled Hours: 40

FLSA Status: Exempt

Earliest Start Date: Immediately

Position Duration: Expected to Continue

Location: AUSTIN, TX

Job Details: GENERAL NOTES: The Center for Biomedical Research Support (CBRS) is a collection of 10 service centers that operates under the Vice President for Research, Scholarship and Creative Endeavors (OVPR) and broadly supports the research community on campus and externally. CBRS serves a central role across all of campus to provide access to cutting-edge technology, expert advice, and centralized services. CBRS is comprised of core facilities including Biomedical Imaging, Bioinformatics, Biological Mass Spectrometry, Biomedical Research Computing, Cryo-EM imaging, Genome Sequencing, Microscopy/Flow Cytometry and Mouse Genetic Engineering. In addition, CBRS provides laboratory support in the forms of stockrooms, electronics repair, and external services drop boxes.  The Microscopy and Imaging Facility (MIF) is a core facility in the Center for Biomedical Research Support at the University of Texas at Austin.  Our mission is to support multidisciplinary research and further scientific knowledge by providing access to state-of-the-art light microscopy, flow cytometry, and other research instrumentation; consultations with our expert staff; instrument trainings; and educational seminars and workshops. We are seeking a skilled and motivated Core Technician to join our team. In this role, you will be responsible for the maintenance, operation, and user training of scientific instrumentation, with a specific focus on light microscopes, flow cytometers, sectioning instruments, plate readers, and gel imagers.  As a member of our team, you will play a critical role in advancing research projects at UT Austin. We provide excellent customer service to our researchers, and we believe in making our instrumentation accessible to any researcher, no matter their previous experience level or knowledge. By training researchers in this role, you will contribute to the development of the next generation of scientists.  Through working in a multidisciplinary core facility, you will gain experience with a wide variety of sample types and experiments. We are looking for someone who can work full-time on-site in the Microscopy and Imaging Facility to provide instrument support and maintenance when needed. UT Austin offers a competitive benefits package that includes:  

  • 100% employer-paid basic medical coverage¬†¬†
  • Retirement contributions
  • Paid vacation and sick time
  • Paid holidays Please visit our Human Resources (HR) website to learn more about the total benefits offered. PURPOSE:¬† This position will support research at the University of Texas at Austin by providing user training on instrumentation, consultations with users on their experiments, and maintenance of instrumentation to ensure data quality, with a specific focus on light microscopes, flow cytometers, sectioning instruments, plate readers, and gel imagers. RESPONSIBILITIES:¬†
  • Trains researchers on the theory and proper operation of instrumentation in the Microscopy and Imaging Facility, with a specific focus on light microscopes, sectioning instruments, gel imagers, and plate readers. Provides ongoing support to researchers for troubleshooting or experiment questions after training.
  • Conducts daily and periodic maintenance of instruments, including light microscopes, flow cytometers, sectioning instruments, gel imagers, plate readers, and related computers. Schedules and coordinates external service technicians as needed. Keeps accurate records of all maintenance performed to ensure quality of experiment data.
  • Operates instruments to acquire data on behalf of researchers. Communicates regularly with researchers on these assisted use projects to discuss their experiment needs and goals.
  • Consults with researchers on experiment design, data acquisition, and analysis.
  • Develops standard operating protocols as needed for new instrumentation or changes in methodology. Keeps accurate records of instrument usage and scheduling.¬†¬†
  • Other related functions as assigned. REQUIRED QUALIFICATIONS:¬†
  • Bachelor‚Äôs degree with at least two years of relevant experience or master‚Äôs degree.
  • Hands-on experience operating a cryostat or similar sectioning instrument.
  • Hands-on experience operating a plate reader and/or gel imager.
  • Hands-on experience operating light microscopes, including fluorescence microscopes.
  • Ability to work independently to complete responsibilities.
  • Organizational and time management skills.
  • Excellent interpersonal skills.
  • Excellent written and verbal communication skills. Relevant education and experience may be substituted as appropriate. PREFERRED QUALIFICATIONS:¬†¬†
  • Experience with light microscope maintenance protocols, including cleaning.
  • Experience with flow cytometry maintenance protocols, including quality control.
  • Experience training others to use scientific instruments.
  • Experience with sample preparation, including fluorescent labeling. SALARY RANGE:¬† $45,000 + depending on qualifications WORKING CONDITIONS:
  • Uniforms and/or personal protection equipment (furnished)
  • May work around chemical fumes
  • May work around standard office conditions
  • May work around biohazards
  • May work around chemicals
  • Repetitive use of a keyboard at a workstation
  • Use of manual dexterity
  • Lifting and moving REQUIRED MATERIALS: Please mark "yes" on the application for required materials.¬†Failure to attach all additional materials listed may affect candidates being considered for the position.
  • Resume/CV
  • 3 work references with their contact information; at least one reference should be from a supervisor.
  • Letter of interest Important¬†for applicants who are NOT current university employees or contingent workers:¬†You will be prompted to submit your resume the first time you apply, then you will be provided an option to upload a new Resume for subsequent applications. Any additional Required Materials (letter of interest, references, etc.) will be uploaded in the Application Questions section; you will be able to multi-select additional files. Before submitting your online job application, ensure that¬†ALL¬†Required Materials have been uploaded. ¬†Once your job application has been submitted, you cannot make changes. Important for Current university employees and contingent workers:¬†As a current university employee or contingent worker, you MUST apply within Workday by searching for Find UT Jobs. If you are a current University employee, log-in to Workday, navigate to your Worker Profile, click the Career link in the left hand navigation menu and then update the sections in your Professional Profile before you apply. This information will be pulled in to your application. The application is one page and you will be prompted to upload your resume. In addition, you must respond to the application questions¬†presented to upload any additional Required Materials (letter of interest, references, etc.) that were noted above.

    Employment Eligibility: Regular staff who have been employed in their current position for the last six continuous months are eligible for openings being recruited for through University-Wide or Open Recruiting, to include both promotional opportunities and lateral transfers. Staff who are promotion/transfer eligible may apply for positions without supervisor approval.

    Retirement Plan Eligibility: The retirement plan for this position is Teacher Retirement System of Texas (TRS), subject to the position being at least 20 hours per week and at least 135 days in length.

    Background Checks: A criminal history background check will be required for finalist(s) under consideration for this position.

    Equal Opportunity Employer: The University of Texas at Austin, as an equal opportunity/affirmative action employer, complies with all applicable federal and state laws regarding nondiscrimination and affirmative action. The University is committed to a policy of equal opportunity for all persons and does not discriminate on the basis of race, color, national origin, age, marital status, sex, sexual orientation, gender identity, gender expression, disability, religion, or veteran status in employment, educational programs and activities, and admissions.

    Pay Transparency: The University of Texas at Austin will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information.

    Employment Eligibility Verification: If hired, you will be required to complete the federal Employment Eligibility Verification I-9 form.  You will be required to present acceptable and original documents to prove your identity and authorization to work in the United States.  Documents need to be presented no later than the third day of employment.  Failure to do so will result in loss of employment at the university.

    E-Verify: The University of Texas at Austin use E-Verify to check the work authorization of all new hires effective May 2015. The university’s company ID number for purposes of E-Verify is 854197. For more information about E-Verify, please see the following:

  • E-Verify Poster (English) [PDF]
  • E-Verify Poster (Spanish) [PDF]
  • Right To Work Poster (English) [PDF]
  • Right To Work Poster (Spanish) [PDF]

    Compliance: Employees may be required to report violations of law under Title IX and the Jeanne Clery Disclosure of Campus Security Policy and Crime Statistics Act (Clery Act). If this position is identified a Campus Security Authority (Clery Act), you will be notified and provided resources for reporting. Responsible employees under Title IX are defined and outlined in HOP-3031. The Clery Act requires all prospective employees be notified of the availability of the Annual Security and Fire Safety report. You may access the most recent report here or obtain a copy at University Compliance Services, 1616 Guadalupe Street, UTA 2.206, Austin, Texas 78701.

Yale School of Medicine, Yale University
Senior Staff Scientist (87647BR)
New Haven, Connecticut
USA
Learn More
Deadline: Sep 1, 2024

The FIB-SEM Collaboration Core (F-SCC) at Yale School of Medicine is seeking a talented, skilled, and highly motivated researcher to assume the role of Senior Staff Scientist (87647BR) to lead and perform the FIB-SEM sample preparation and image acquisition operations. At the forefront of volume Electron Microscopy, the F-SCC utilizes the state of the art enhanced Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) technology for large volume imaging with nanometer isotropic resolution. Under supervision of the Director, the candidate will be responsible for pipeline processes of X-ray guided FIB-SEM sample preparation, enhanced FIB-SEM image acquisition, and image registration and alignment. The candidate is expected to be multi-tasking, perform independent experiments using the state-of-the-art laboratory techniques including enhanced Focused Ion Beam Scanning Electron Microscopy and X-ray micro-CT. The candidate will work closely with supervisor, group members, and collaborators.

Johnson & Johnson
Principal Scientist, Cryo-EM
Spring House, Pennsylvania
USA

Johnson & Johnson is recruiting for a Principal Scientist, Cryo-EM, located in Spring House, PA.

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com/

The Discovery Technologies and Molecular Pharmacology group is a dynamic, diverse and critical part of the Discovery Sciences organization in Janssen R&D. We are committed to the discovery and characterization of high-quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Areas. This mission requires deep scientific expertise across broad disciplines including chemistry, cellular and molecular pharmacology, enzymology, screening, protein science, and structural biology coupled with an ability to work collaboratively with internal and external partners. Building on a strong legacy of success, we are currently seeking an outstanding and motivated individual to join our team as a Principal Scientist, Cryo-EM.

Key Responsibilities: Be an active member of drug discovery teams, working closely with computational and medicinal chemists on structure-based drug design approaches for small/large molecule optimization. Be responsible for end-to-end high-resolution structure determination via Cryo-EM including sample and cryo-EM grid optimization, data collection, processing, and structure refinement, and communicating these results to the project teams. Collaborate closely with protein scientists, biophysicists, protein NMR, and X-ray crystallography scientists as part of an integrated structural biology effort. Actively seek innovative strategies to handle complex targets including grid preparation, data collection, processing, and analysis. Contribute to increasing the structural biology scientific expertise of the group by publishing high-impact research papers, attending and presenting at scientific conferences, internalizing impactful outside technologies and techniques, and establishing academic collaborations. Mentor lab scientists and contribute to the strategic planning of the Structural Biology group. QUALIFICATIONS Education:

Ph.D. or equivalent and postdoctoral experience in structural biology (Cryo-EM, X-ray crystallography, biophysics, protein engineering) or related field is required Experience and Skills: Required:

Minimum 3 years of industry experience is required Deep scientific expertise in structural biology, with strong experience in sample preparation using Vitrobot, data collection via EPU, and structure determination are required Strong record of external publications and presentations is required Outstanding written and oral communication skills are required Preferred: Experience in cryo-ET/FIB milling, and Micro-ED is preferred Experience in machine learning and docking programs (e.g., Schrödinger) is preferred Experience in structure-guided small/large molecule design utilizing Cryo-EM/X-ray is preferred Knowledge of protein production techniques and protein stability requirements is preferred Broad knowledge of biophysics (such as ITC, DSF, SPR, ASMS, HDX-MS), biochemistry, molecular pharmacology, and protein sciences is preferred Expertise in one or more of the following therapeutic areas: Oncology, Inflammation, Neuroscience, Cardiovascular, and Infectious Diseases is preferred Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com

CRUK Cambridge Institute (CRUK CI)
Microscopy Specialist (Scientific Associate, Senior Scientific Associate)
UK
Europe

The CRUK Cambridge Institute's (CRUK CI) scientific Core Facilities perform a fundamental role at the heart of our research community. They are a repository for deep knowledge and expertise in scientific technologies and techniques and work in partnership with the Institute's research groups in answering biological questions related to cancer. The Light Microscopy Core Facility provides expertise, training, and instrumentation across a wide range of research projects. We support 5000 hours of yearly microscope usage for our 200 researchers at the CRUK CI and the wider community. The supported technologies include Confocal, High Content, Light Sheet, STED Super-resolution and Widefield Microscopy as well as a wide range of image analysis. We are looking for a Microscopy Specialist to join our team to provide scientific and technical support and training in microscopy and image analysis to members of the research groups. The role holder will assist with the day to day running of the Microscopy Core Facility including maintaining the microscopy equipment. You will have the opportunity to apply your problem-solving skills to troubleshoot challenging technical issues, analyse image data and contribute towards a large range of research projects in the CRUK CI. The Microscopy Specialist reports directly to the reports directly to the Light Microscopy Facility Manager, Andreas Bruckbauer and will be part of a team of currently four facility staff supporting research assistants, research associates, clinical fellows, and PhD students from the research groups. The role holder would possess in-depth experience in confocal microscopy and image analysis at a level sufficient to provide training to inexperienced users. Expertise in other advanced microscopy techniques such as Super-Resolution microscopy or Light Sheet microscopy is desirable (required for the Senior Scientific Associate). Ideally you would have experience of working in a Microscopy Core Facility team and will possess excellent communication and teamwork skills. Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online. Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application. Please include details of your referees, including email address and phone number, one of which must be your most recent line manager. The closing date for applications is: 6th May 2024 The interview date for the role is: To be confirmed Please quote reference SW41069 on your application and in any correspondence about this vacancy. The University actively supports equality, diversity and inclusion and encourages applications from all sections of society. The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

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