Job Openings

An exciting opportunity has arisen for an Optical Microscopy Support Specialist to join the Bioimaging Platform at the John Innes Centre in Norwich in the East of England. This is a fulltime, permanent position. Closing date: 11th August 2025.

About the John Innes Centre: The John Innes Centre is an independent, international centre of excellence in plant and microbial sciences. We nurture a creative, curiosity-led approach to answering fundamental questions in bioscience, and translate that knowledge into societal benefits. Our strategic vision, Healthy Plants, Healthy People, Healthy Planet, sets out our ambitious long-term goals for the game changing impact of our science globally. 

About the Bioimaging Platform: This position will be based within the Bioimaging Platform, which caters to the light and electron microscopy needs of the research groups at the John Innes Centre (JIC) in Norwich. We provide extensive microscopy services, training, and technical support to JIC scientists, and also collaborate on imaging projects across the wider Norwich Research Park. On the optical microscopy side we have four scanning confocal microscopes (Zeiss LSM980 Airyscan Multiplex and LSM880 Airyscan fast, Leica Stellaris 8 FALCON with FLIM/FCS and SP8 TCSPC with Picoquant FLIM), a Zeiss Elyra PS1 and an Elyra 7 SIM microscope, three Zeiss epifluorescence microscopes and two Zeiss Axio Zoom V16 fluorescence stereo microscopes. In addition, there is an array of sample preparation equipment. The electron microscopy side of the platform features a field-emission transmission electron microscope (TEM) and two field-emission scanning electron microscopes (SEM) with cryo-systems, including one with a 3View system for serial block-face SEM as well as specimen preparation equipment for electron microscopy.

The role: We are seeking an enthusiastic and motivated Optical Microscopy Support Specialist to join our Bioimaging Platform at a world-leading institute in a full-time, indefinite post. The post holder will train users on all the light microscopes, collaborate on imaging projects, provide technical support including some sample preparation, give talks at the annual light microscopy course and help with the development of advanced technologies such as (FRET-)FLIM and FCS. A second aspect of the role is to give advice and collaborate on image analysis projects. The post holder will work closely with the Senior Optical Microscopist.

The ideal candidate: The ideal candidate will have experience with various light microscopes, esp. scanning confocal microscopes. A knowledge of quantitative techniques such as (FRET-)FLIM, FCS and FRAP is highly desirable as is experience in user training on instruments. Experience in microscope maintenance/trouble shooting would be welcomed but those skills can be acquired on the job. It is essential that the candidate has an interest in image analysis and coding and experience in image analysis software (Fiji, Arivis) and Python/Java programming would be ideal. Opportunities to attend technical training courses will be provided. Experience in applying AI to image analysis would be a bonus but this skill can be acquired while in post. Excellent communication skills are essential for user training, presentations and collaborations with research groups.

Additional information: For further information and details of how to apply, please visit our website http://jobs.jic.ac.uk or contact the Human Resources team on 01603 450814 or nbi.recruitment@nbi.ac.uk quoting reference 1004919. Interviews will be held on Monday 15th September. For informal enquiries please contact Eva Wegel at eva.wegel@jic.ac.uk.

A core aspect of Si-M’s research agenda is the development, refinement, and application of human model systems to simulate physiological and pathophysiological processes in a translational context. Consequently, high-resolution, light microscopy-based analysis of diverse tissue types—including 3D ex vivo cultures, biopsies, and stem cell-derived organoids in static and dynamic (fluidic) systems—constitutes a key focus of numerous research projects. The platform is equipped with a comprehensive suite of high-end microscopy systems and complementary analytical infrastructure.

• Operational and research-oriented leadership of the Microscopic Imaging Platform as a shared facility
• Personnel leadership, budget responsibility, and resource management
• Operation and quality assurance of the technical infrastructure
• User support, consultation, and training
• Participation in scientific collaboration projects and acquisition of third-party funding
• Implementation of quality, risk, and safety management systems

For further details please check out the official announcement linked in the URL!

The Opportunity

The position is focused on developing novel hardware technologies to extend the capabilities of cryogenic FIB-SEM to enable a deeper understanding of cell architecture and function at molecular resolutions. In this, the 3D cellular structure of unstained, vitrified cells is to be systematically imaged at the highest possible resolutions. The challenge is that contrast of non-lipid structures is very low in the SEM, and the research will focus on developing alternative contrast strategies using an in-tool AFM. This on-site position will be based in Redwood City, CA.

What You’ll Do:

• Develop improved methods and workflows for imaging and analyzing unstained biological samples within the FIB-SEM (with AFM)
• Explore novel approaches for successively imaging the surface of FIB-milled vitrified biological samples using the AFM or related scanning probe optical methods 
• Collaborate closely with platform and technical research teams at CZII
• Collaborate broadly with the scientific community
• Write papers and present findings at scientific conferences
• Mentor and train junior researchers in the lab
• Keep up-to-date with the latest research in the field and identify new areas of investigation.
• You will understand the challenges and opportunities for the Institute, and prioritize where to focus our efforts in biological research as well as how to best apply novel technology developments to provide the highest impact and results to the scientific community You have: 
• PhD in Chemistry, Physics, Engineering or related field
• A strong track record of research accomplishments in AFM imaging
• Excellent analytical skills 
• Ability to design and fabricate instrumentation
• Ability to work independently as well as part of a team
• Excellent written and verbal communication skills
• Outstanding attention to detail, accuracy, and procedures
• Must have the ability to multitask and work with technology developers in a highly collaborative environment

  Nice to have: 

• Experience with cryogenic imaging
• Python or other coding expertise
• FIB-SEM on biological samples
• Near-field optical imaging experience

  Compensation:

  The Redwood City, CA base pay range for this role is $108,000.00 - $148,500.00. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. 

I would like to share an exciting opportunity at Karolinska Institutet, where we are currently recruiting 20 Assistant Professors with a strong focus on scientific excellence. At the Department of Medicine, Huddinge (MedH), we are looking to recruit up to two Assistant Professors in the fields of molecular or translational medicine. We are seeking early-career researchers with a strong scientific drive and the ambition to grow in an international, collaborative environment. As part of MedH, new faculty members will benefit from:

• Strong academic mentorship and career support
• Access to state-of-the-art infrastructure and a modern preclinical animal facility
• Rich clinical cohorts and biobank resources
• A competitive salary and a generous startup package
• A vibrant research environment spanning stem cell biology, immunology, infectious diseases, hematology and cancer, gastroenterology and hepatology, cardiovascular research, nutrition, metabolism and diabetes, and aging
• A fantastic microscopy core facility! :) The position is open to international applicants and includes a generous funding package. Please help us spread the word! Application deadline: 2 September 2025 More information and application: Assistant Professor in molecular or translational medicine

The University of Wyoming Science Institute and the University of Wyoming Office of Research and Economic Development invites applications for the director of the new Center for Advanced Scientific Instrumentation (CASI) (https://www.uwyo.edu/science-initiative/casi) beginning in the Fall of 2025. Applicants with experience in quantitative imaging techniques from all fields of physical and life sciences are encouraged to apply. ESSENTIAL DUTIES AND RESPONSIBILITIES:

The research project concerns the development and use of MINFLUX single-molecule microscopy for cellular imaging and dynamic studies on the nanoscale. 

As an expert in light microscopy you will join a core facility team as a consultant for researchers at Novartis Basel. You will also play a key part in supporting scientific projects by advising users, coordinating resource sharing, and contributing to the maintenance and optimization of microscopy infrastructure.

Explore the Frontiers of Materials Characterization.  This fully funded PhD position at DTU Nanolab offers the chance to work at the forefront of research addressing one of today’s most pressing environmental challenges: water contamination by persistent pollutants. In this project, you will explore how nanoporous materials interact with organic contaminants at the molecular level. Using advanced electron microscopy techniques, you will investigate structure–property relationships at the nanoscale to help develop next-generation materials for water purification. Your work will involve visualizing molecule–nanopore interfaces and uncovering the structural and chemical dynamics that govern adsorption processes. This interdisciplinary research is part of a joint research project between DTU Nanolab and Dr. Romy Ettlinger’s group at the Technical University of Munich (TUM), which specializes in designing porous materials for environmental remediation. You will contribute to a deeper understanding of how to engineer materials that can effectively remove harmful substances from water, with real-world impact on sustainability and public health.

The Bowman lab is seeking to recruit a postdoctoral fellow to develop novel instrumentation and methods for high-speed optical microscopy. We have developed nanosecond imaging techniques that enable new approaches for achieving fast, quantitative measurements of fluorescent biosensors. Using these approaches, we are building customized microscopes from the ground up to enable imaging of complex cellular signals in vivo and in 3D tissue environments. Our work is interdisciplinary by nature, and candidates may come from many different backgrounds including engineering, physics, bioengineering, and neuroscience. For this role we are seeking applicants with prior experience developing optical and/or electronic instrumentation and methods. For example, candidates may have experience building (1) Microscopes – e.g. fluorescence, nonlinear, super-resolution, or label-free techniques, (2) Laser, optical, or atomic physics experiments, (3) Instrument control systems, RF electronics, or image data analysis pipelines, or (4) Imaging and electrophysiology systems for in vivo measurements. We are committed to working across disciplinary boundaries and to providing a training environment with strong mentorship and career development opportunities. Candidates will have significant opportunities for creativity in defining project directions and will have the chance to participate in fruitful collaborations both within Salk and with external research groups.

The Euro-BioImaging Bio-Hub hosted by the European Molecular Biology Laboratory (EMBL) is looking for a highly motivated science professional and manager to support EC-funded projects, in particular IMAGINE, including technology validation by our Nodes and user project management, relevant engagement with the imaging community and outreach activities to researchers in the life sciences, as part of the operation of the European research infrastructure Euro-BioImaging ERIC (www.eurobioimaging.eu). Euro-BioImaging ERIC offers life scientists open access to imaging instruments, expertise, training opportunities, and data management services that they do not find at their home institutions or among their collaboration partners. All scientists, regardless of affiliation, area of expertise, or field of activity, can benefit from these pan-European open access services. Euro-BioImaging offers state-of-the-art imaging services through its internationally renowned facilities called Nodes. These Nodes are distributed across Euro-BioImaging’s 19 members. The management entity of Euro-BioImaging, the so-called Hub, is distributed across three sites: the legal seat is based in Finland, the Med-Hub in Italy, and the Bio-Hub is hosted by EMBL in Heidelberg, Germany. This post is for the Bio-Hub at EMBL. Your role  IMAGINE is an EC funded project coordinated by EMBL for developing and establishing “Next generation Imaging technologies to probe structure and function of biological specimen across scales in their natural context”.   The goal of this cross-disciplinary initiative is to develop next generation of scale-crossing imaging technologies needed to enable an integrated investigation of structure and function of biological systems, and to bring those technologies not only to highly specialized central facilities and standard laboratory models, but also out in the field, at Europe’s coastline and on the ocean. For achieving this goal, the IMAGINE consortium brings together leading European technology developing institutions, with leading industrial companies and the pan-European RIs in structural biology, bioimaging and marine biology. Integrating the expertise and domains of the individual project partners, the IMAGINE project focuses on developing and integrating four major microscopy technologies: X-ray imaging, cryo electron microscopy, cryo and dynamic super-resolution microscopy and large volume intravital light microscopy. It furthermore develops the AI-powered image analysis and data integration/sharing capabilities. The Euro-BioImaging Bio-Hub (EMBL) is coordinating the validation of the newly developed technologies, tools and workflows for service readiness in collaboration with Euro-BioImaging Nodes (WP7), setting up procedures for advanced training of Research Infrastructure staff on the developed technologies together with the project partner Instruct and EMBRC (WP10), and fostering Integration of the newly developed services in core facilities across European RIs (WP11).   The successful applicant will lead IMAGINE WP7 and WP11, and manage relevant aspects of the Euro-BioImaging operation, deliverable and milestones in the consortium, supporting Euro-BioImaging tasks related to project implementation through IMAGINE. Responsibilities include but are not limited to:

• Working closely with the IMAGINE project partners developing the new integrative technologies to achieve a seamless transition from technology development to validation
• Contribute to implementation of validation guidelines and processes for effective incorporation of new technologies into future Euro-BioImaging services in close collaboration with experts and the Euro-BioImaging Nodes
• Foster and monitor validation of developed Bioimaging technologies with selected use cases at Euro-BioImaging Nodes
• Support procedures and workflows (roadmap) for integrating the validated IMAGINE technologies into cross-RI services pipelines
• Promote the exchange of experience between the different RIs with the goal of seamless integration of new technologies for service
• Provide consultation, administrative and management support for recruiting and implementing cross-RI demonstrator user projects from academia or industry implementing the newly developed services and correlative pipelines – for validating the workflows interoperability
• Representing imaging community needs in the development of IMAGINE
• Support the delivery of trainings and organisation of workshops for Research Infrastructure staff on the newly developed imaging technologies
• Reporting on project progress and outcomes to the EC as funder
• Communication and outreach activities to advertise Euro-BioImaging’s service portfolio in national and international life sciences’ events
• Strategic support for the Euro-BioImaging Hub and Nodes in preparing for participation in future Horizon Europe consortia
• Outreach to other European Research Infrastructures in the life sciences, also for supporting advanced user projects with requests for common access The successful applicant will be integrated into the international Bio-Hub and Hub team, working closely together with colleagues that are professionals in the fields of imaging technologies, project management, administration, communication & outreach, image data analysis and science policy. They will support the Head of Operations and the Director of the Bio-Hub at EMBL. You have 
• PhD in the life sciences ideally followed by additional professional experience in academia or industry or equivalent experience (postdoctoral training, service provision in a core facility, science project management, etc.).
• Experience in advanced biological imaging technologies.
• Experience in scientific project management in a competitive research environment.
• Proven ability to effectively interact with multiple stakeholders on international and interdisciplinary level and the ability to move between the scientific and managerial level.
• Excellent organisational, management, prioritising, communication, and interpersonal skills.
• Passionate about improving research conditions for European scientists by providing services to the community with a high motivation to leave an impact at work.
• Excellent problem-solving skills and the ability to proactively identify promising solutions even when working under tight deadlines.
• Fluency in written and spoken English. We are looking for a motivated self-starter with an open attitude towards new responsibilities and tasks. The successful applicant will have an intrinsic motivation to deliver, be well structured, rigorous and able to work independently. We welcome a creative, problem-solving colleague, who enjoys working in an international interdisciplinary team within a highly collaborative atmosphere. You may also have
• Experience in user support in microscopy facilities.
• Experience in funding acquisition and reporting duties.
• Experience in communication, marketing and professional networking. Contract length: 2,5 years Salary: Grade 5 (monthly salary starting from 3.9k EUR after tax) + other paid benefits based on personal circumstances 

NES Fircroft is recruiting a Senior Research Scientist to join a leading agricultural company dedicated to enhancing global food security. This role is based at our client's site in Bracknell on a 24-month contract. As a Senior Research Scientist, you will be part of the microscopy team within the Bioscience function in Crop Protection. You will conduct research on various projects related to structural studies or phenotyping changes from active ingredients.

Key Responsibilities:

• Provide proactive scientific and technical support for microscopy requests/tasks by performing studies using fluorescence or electron microscopy.
• Demonstrate proficiency with microscopy techniques (fluorescence and electron-based).
• Execute operational priorities as agreed with the Science Leader.
• Interpret and analyse data, presenting conclusions in detailed reports and presentations.
• Implement HSE actions to ensure operations meet defined standards

Qualifications:

• A BSc or MSc (preferred) or PhD in a relevant field related to microscopy and bioimaging.
• At least 1-2 years of laboratory-based experience.
• Proven experience in imaging plant or insect materials using optical and electron microscopy.

For more information on the role please contact Jade Stirk at jade.stirk@nesfircroft.com

Postdoctoral Fellow - Biomolecular Condensates, Protein Dynamics & GI Disease Weill Cornell Medicine - Division of Gastroenterology and Hepatology

The Platt Lab in the Division of Gastroenterology and Hepatology at Weill Cornell Medicine invites applications for a postdoctoral research position in molecular and cellular biology. We investigate how changes in protein mobility and biomolecular condensates contribute to human disease, with a particular focus on gastrointestinal pathophysiology.

The successful candidate will lead projects using advanced imaging techniques, including fluorescence recovery after photobleaching (FRAP) and single-particle tracking (SPT), to uncover how environmental stressors disrupt biomolecular condensates and protein dynamics. Our goal is to reveal disease mechanisms and identify tractable therapeutic targets. We are a newly established and growing lab that values scientific rigor, creativity, and collaboration.

Responsibilities

• Design and execute independent experiments using advanced imaging and molecular biology techniques
• Analyze protein mobility using quantitative imaging and computational tools
• Contribute to manuscript and grant writing
• Present research findings at internal seminars and external conferences
• Collaborate across disciplines to explore emerging models of disease pathogenesis

Qualifications

• PhD, MD/PhD, or equivalent degree in molecular biology, biophysics, systems biology, or a related field
• Strong background in imaging, microscopy, and cell biology
• Experience with image analysis software (e.g., ImageJ/FIJI, MATLAB, Python)
• Interest or experience in biomolecular condensates, protein dynamics, and/or redox biology
• Demonstrated ability to publish high-quality scientific work
• Creative, collaborative, and motivated to uncover fundamental disease mechanisms

Application Instructions To apply, please send the following to Dr. Jesse Platt at jep4025@med.cornell.edu:

• A one-page cover letter describing your research background and interests
• CV with a list of publications
• Contact information for 2–3 references The position is available immediately and will remain open until filled. Salary range: $61,008 – $74,088, based on experience and in accordance with WCM’s minimum stipend policy. Weill Cornell Medicine is an equal opportunity employer and encourages applications from candidates of diverse backgrounds. Learn more about our work: https://www.linkedin.com/in/jesse-platt-md-phd-a3a42621/

This PhD project will systematically explore the function of squamous cyst cells in the Drosophila testis and how their internal structure facilitates communication with neighbouring germ cells and coordinates tissue-wide responses leading to sperm production. The Drosophila testis is a powerful system, as its simple morphology is combined with sufficient complexity and cellular conservation. Stem cells and differentiating cell types are well-characterised and can be easily traced, while phenotypes can be studied in vivo. To this end, you will use state-of-the-art Drosophila genetic and advanced protein-interaction techniques as well as high-resolution light and electron microscopy. Our findings will impact researchers in stem cell & developmental biology, regenerative medicine, disease modelling and translational research in the longer-term, by targeting the altered signalling networks in squamous cell carcinomas and creating novel therapeutics to treat human disease. You will be part of a dynamic environment and vibrant PhD community at Medway School of Pharmacy and the Universities of Kent and Greenwich at Medway Campus. You will have access to fully operational fly and molecular lab, shared microscopy and proteomic facilities, and will work alongside our world-renowned collaborators with complementing expertise.

For information about the project contact Dr Fani Papagiannouli: f.papagiannouli-227@kent.ac.uk

The Neuron Signaling Lab at NUS is seeking a motivated and skilled Research Fellow to join our interdisciplinary neuroscience team. We use advanced optical imaging and behavioral analysis to uncover how molecular pathways shape brain function, aiming to bridge molecular and systems neuroscience.

Our core platforms include: § 3D & 4D confocal fluorescence microscopy § 1P & 2P fluorescence microendoscopy § Fiber photometry & optogenetics § Genetically encoded molecular tools We focus on behaviors such as reward learning, fear learning and motor learning, with strong interest in primary cilia and nuclear signaling in the brain.

Position Summary: We seek a candidate with strong expertise in microscopy and computational image analysis to: 1. Support and enhance ongoing imaging projects in the lab 2. Develop AI-powered pipelines for analysis of microendoscopic calcium imaging, confocal fluorescence microscopy, and behavioral videos 3. Lead cross-modality image registration applications 4. Launch new projects that leverage our optical expertise to probe brain function

Preferred Qualifications & Expertise: § PhD in neuroscience, bioengineering, computational biology, or related field § At least one strong first-author publication in microscopy and/or image analysis is required § Strong background in optical imaging principles and microscopy (e.g., confocal, 2P, STED, or light sheet) § Demonstrated experience in image processing, quantitative analysis, and biological interpretation § Proficiency in AI/machine learning tools for image segmentation, transformation, registration, or tracking § Solid mathematical foundation for image analysis (e.g., affine transformations, convolutional filters, matrix and morphological operations) § Programming skills in Python, MATLAB, and/or experience with ImageJ, Napari, Imaris, TensorFlow, or PyTorch § Familiarity with in vivo imaging, optogenetics or spatial transcriptomics methods is a plus § Strong interest in bridging biological questions with quantitative approaches § Excellent problem-solving, collaborative, and communication skills

Environment & Opportunities: Our lab is part of a highly multidisciplinary research environment, with close collaborations in biochemistry, neural computation, and genomics. The successful candidate will be embedded in a vibrant scientific community and have access to a full suite of optical and behavioral neuroscience platforms. In addition to technical capability, we are looking for an individual excited by our novel multi-scale approach to neurobiology and eager to tackle complex, integrative questions.

The subject covers the development and application of innovative methods that use light to explore biological systems and processes at the molecular, cellular, and tissue levels. It includes experimental light microscopy and image analysis, such as super-resolution and light-sheet microscopy, within various disciplines like biology and medicine.

Duties

The duties include responsibility for the national research infrastructure NMI (National Microscopy Infrastructure) and the research infrastructure ALM (Advanced Light Microscopy) at SciLifeLab, at 50%. The senior lecturer is expected to participate in the development of existing courses at the undergraduate, advanced, and doctoral levels within the unit for biophysics. Supervision of bachelor's and master's theses, as well as doctoral supervision, is included. The research should focus on method development within the field. The research must ensure that the research infrastructure, the national infrastructure, and teaching stay aligned with the development within the field. The senior lecturer is expected to be able to teach in Swedish within three years, and if necessary, a language plan will be created in connection with the appointment as support.

Yale School of Medicine https://medicine.yale.edu/fib-sem/ The FIB-SEM Collaboration Core (F-SCC) at Yale School of Medicine is seeking a Senior Staff Scientist to join our pioneering team at the forefront of volume electron microscopy. The F-SCC leverages cutting-edge enhanced Focused Ion Beam Scanning Electron Microscopy (eFIB-SEM) technology to achieve large-volume imaging at nanometer isotropic resolution.

Position Summary: Under the supervision of the F-SCC Director, the Senior Staff Scientist will manage the image acquisition pipeline. Responsibilities include:

• Performing X-ray-guided FIB-SEM sample preparation
• Conducting enhanced FIB-SEM image acquisition
• Carrying out image registration, alignment, segmentation, and data analysis The successful candidate will be expected to work independently, multitask effectively, and perform experiments using advanced laboratory techniques, including enhanced FIB-SEM and X-ray micro-computed tomography (micro-CT). Collaboration and close communication with the supervisor, collaborators, and core members are essential.

Qualifications:

• Strong expertise in electron microscopy and related imaging technologies preferred
• Ability to manage multiple projects simultaneously and work independently
• Excellent teamwork, communication, and organizational skills

Consideration: please submit an application and cover letter describing how your previous research accomplishments and scientific interests fit with the scope of the research via this link.

Van Andel Institute (VAI), is seeking to hire an Image Analyst (Core Bioinformatician) within our Optical Imaging Core. The Optical Imaging Core (OIC) provides imaging services for VAI and collaborating institutions. Its goal is to serve the VAI community with state-of-the-art imaging resources to address a broad variety of research questions, as well as offering the expertise to train researchers to use these resources effectively. As an Image Analyst on our team, you will assist researchers by providing technical and computational expertise to accomplish their goals through bioimage analysis. In this role, you will be responsible for developing and supporting advanced image analysis workflows, including but not limited to Python-based image processing/analysis pipelines, training of novel machine learning models, bespoke pipelines with existing image analysis software, and FAIR use protocols for reproducible, unbiased image-based assays. You will collaborate with our existing image analyst as well as work directly with PIs and researchers to help design and optimize imaging experiments for appropriate downstream analyses.

The successful candidate will be an integral part of a team whose aim is to discover the next generation genetic therapies for a wide range of indications. The position requires enthusiasm, passion, attention to detail, and a desire to create new medicines for patients.