Want to devote your expertise in data science to accelerate the pace at which new medicines are found? The Carpenter-Shen lab develops and applies methods to extract quantitative information from high-throughput biological images, integrated with other omics.

King’s College London are recruiting a Facility Manager to lead their newly established Cryo-EM Structural Discovery Facility. This is an exciting opportunity for an experienced cryo-EM specialist to support cutting-edge structural biology research, shape the development of a growing facility, and work with researchers across academia and industry using state-of-the-art instrumentation. If you're passionate about advancing research through technical expertise and collaboration, the team would be keen to hear from you. 

  Job Description - Electron Microscopy Technician Chief, Cell Biology (946510)

Job Description

Electron Microscopy Technician Chief, Cell Biology - (946510)

Description

  THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER

JOB INFORMATION

Job Code: 4381 Job Title: ELECTRON MICROSCOPY TECH CHIEF Date Last Edited: 2/17/2026 FLSA Status: N

JOB SUMMARY Works independently with full technical authority to direct electron microscopy core-facility operations. Serves as the institutional subject-matter expert for electron-microscopy methods, instrumentation, and workflows. Establishes facility-wide technical standards, oversees advanced research and clinical EM services, and ensures alignment with institutional research priorities. Serves as the core facility authority for electron microscopy services. Operates fully independently to manage instrument suites, develop facility-wide protocols, and drive innovation in sample preparation and imaging. Provides strategic technical consultation to internal and external stakeholders, ensuring the core meets both research and clinical objectives.

ESSENTIAL FUNCTIONS

Job Duties

• Directs day-to-day operations of the electron microscopy laboratory, ensuring reliable, efficient, and high-quality delivery of EM services in alignment with the Director's scientific vision and priorities.
• Provides advanced technical and operational leadership for electron microscopy workflows, instrumentation, and service offerings; oversees EM personnel to ensure consistent execution of approved methods and standards.
• Applies deep expertise in TEM/SEM systems and advanced EM modalities, to guide operational decisions, assess technical feasibility, and support implementation of new methods and protocols developed under the Director's direction.
• Coordinates laboratory duties, schedules, project activities, instrument usage, operating time, billing, and space utilization to support multiple concurrent research and/or clinical projects.
• Oversees readiness and availability of EM instrumentation and technical resources, including coordination of service, maintenance, calibration schedules, and downtime planning to minimize disruption to users.
• Supervises laboratory and administrative personnel, and support staff; manages staffing levels, assignments, onboarding, and professional development in accordance with institutional guidelines.
• Operationalizes new electron microscopy methods and protocols by coordinating staffing, training logistics, documentation/SOP finalization, safety review, and compliance requirements in collaboration with scientific leadership.
• Orders and allocates laboratory supplies, materials, and equipment; manages inventory, vendor relationships, service contracts, warranties, licenses, and permits to ensure continuity of operations.
• Ensures compliance with safety, regulatory, and institutional requirements; oversees training programs, documentation systems, audits, and corrective actions related to EM laboratory operations.
• Monitors and reports laboratory performance metrics, including utilization, turnaround time, staffing efficiency, and operational costs; supports budgeting, forecasting, and resource planning.
• Identifies operational risks and technical bottlenecks; escalates scientific decisions to the Director while independently resolving administrative, staffing, and operational issues.
• Performs other duties as assigned.

QUALIFICATIONS

Education and Experience

Required

• Education
• Master's Degree in a relevant scientific, engineering, or biomedical field or
• Bachelor's Degree in a relevant scientific, engineering, or biomedical field
• Experience
• 3 years of progressively responsible electron microscopy experience, demonstrating increasing leadership over EM operations, instrumentation, and service delivery with a Master's Degree or
• 5 years of progressively responsible electron microscopy experience, demonstrating increasing leadership over EM operations, instrumentation, and service delivery with a Bachelor's Degree

Knowledge, Skills and Abilities

• Work requires advanced, in-depth knowledge of electron microscopy methodologies, instrumentation, and data quality standards sufficient to oversee and govern day-to-day EM operations.
• Work requires independent judgment and high-level problem-solving related to operational execution of EM services, while escalating final scientific decisions to the Director.
• Work requires accountability for facility-wide instrumentation performance, operational readiness, and adherence to specimen-handling and data-quality standards.
• Work requires advanced organizational and communication skills to coordinate complex, multi-user EM workflows, manage competing priorities, and ensure consistent execution of approved methods.
• Work requires excellent vision for close work.
• Work requires expert-level understanding of EM workflows and techniques, including the physical, spatial, and quantitative principles underlying advanced microscopy, even when not performing routine hands-on work.
• Work requires strong written and oral communication skills, including the ability to author and maintain SOPs, operational documentation, training materials, and internal guidance.

PHYSICAL DEMANDS/WORKING CONDITIONS Physical Demands

• Eye/Hand/Foot Coordination
• Talking Working Conditions
• Hazards
• Laboratory Setting

PACT STATEMENT The following is the acronym, "PACT", and is fundamental to all non-clinical positions at UT Southwestern Medical Center:

• P-Problem Solving: Employees take ownership in solving problems effectively, efficiently, and to the satisfaction of customers, or managers. They show initiative in addressing areas of concern before they become problems.
• A-Ability, Attitude and Accountability: Employees exhibit ability to perform their job and conduct themselves in a professional and positive manner reflecting a professional environment readily assuming obligations in a dependable and reliable manner.
• C-Communication, Contribution, and Collaboration: Who are our Customers? Anyone who requests our help, needs our work product, or receives our services. Employees focus on customer service with creative solutions while improving the customer experience through clear, courteous, and timely delivery and communication. Sharing ideas with others helps expand our contribution to department goals.
• T-Teamwork: Employees work to contribute to the department's success by supporting co-workers, promoting excellence in work product and customer service, and in maintaining a satisfying, caring environment for each other. Salary Salary Negotiable

Security This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

EEO Statement UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.     Primary Location: Texas-Dallas-5323 Harry Hines Blvd Work Locations: 5323 Harry Hines Blvd 5323 Harry Hines Blvd  Dallas 75390 Job: Research & Laboratory Organization: 353001 - CB-Core EMCF Schedule: Full-time Shift: Day Job Employee Status: Regular Job Type: Standard UTSW Job Grade: University Classified Grade 22 Job Posting: Jun 18, 2026, 1:07:15 PM

The life sciences increasingly depend on advanced services offered by core facilities, synchrotrons, data services and other research infrastructures, creating a need for highly-skilled professionals who can operate, improve and expand these scientific services. EMBL’s ARISE2 programme offers over 20 fully funded, three-year postdoctoral fellowships for researchers with STEM backgrounds who are interested in advancing their careers in research infrastructures in academia or industry.

Your role ARISE2 fellows will: • Develop a method or development within EMBL’s areas of expertise, with potential for broader service application • Receive structured training in the operation and management of research infrastructures, including service provision, project and staff management, innovation, and science policy, FAIR principals and AI. • Build professional networks through secondment and job shadowing at EMBL and ARISE2 partner organisations ARISE2 projects should align with EMBL’s research areas—such as genomics, structural biology, imaging, cell and tissue biology, environmental research, and translational applications—while contributing to the development of services that support the wider life science community.

You may develop projects in fields including • Data and computational science: Bioinformatics, AI/ML, computational modelling, software engineering, data management, data science. • Imaging and optical engineering: Imaging and image analysis, optical engineering, detector development, microscopy, X-ray optics • Structural Biology and Mechanical Engineering: Automation, high-precision mechanics, microfluidics, robotics, X-ray crystallography • Biotechnology: (Bio)chemical engineering, chemistry or chemical biology, omics technologies.

You have • A Ph.D. at the time of the call deadline (September 30, 2026). Researchers who have successfully defended their doctoral thesis but who have not yet been formally awarded the degree are eligible to apply. • A university degree in a relevant STEM discipline (Science, Technology, Engineering and Mathematics) • Experience in technology development – experience can be from academia and/or industry and should be relevant to the research fields of our group and team leaders who are participating in the call • Strong research potential that can be illustrated by a diverse set of research outputs (e.g., publications, software, data sets, patents, technical documentation, contribution to technology development or other innovative research etc.) • Ability to work independently and collaborative settings • Excellent communication skills and fluency in English • Good organisational and time-management skills

You might also have • Experience in the improvement or development of methods, techniques or technology for service provision. ARISE2 receives funding from HorizonEurope under the Marie Skłodowska-Curie action COFUND (grant agreement No 101178241).

Why join us EMBL is Europe’s flagship research laboratory for the life sciences – an intergovernmental organisation performing scientific research in disciplines including molecular biology, physics, chemistry and computer science. We are an international laboratory with more than 1800 employees from many nations, operating across six sites, in Heidelberg (HQ), Barcelona, Hinxton near Cambridge, Hamburg, Grenoble and Rome. One of our missions is to provide access to advanced technologies and engage in technology transfer activities. EMBL is a curiosity-driven, community-oriented and international organisation. As an inclusive, equal opportunity employer, we believe that diversity enables us to collaborate more effectively and be innovative in our approaches. We are, therefore, committed to creating an inclusive and flexible culture - one where everyone can realise their full potential and make a positive contribution to our organisation. We operate by our values of: openness, inclusion, integrity, transparency, fairness. At EMBL, as per our Equality, Diversity and Inclusion Strategy, we actively encourage applications from people who are currently underrepresented in science. We also welcome applications from researchers at risk and applicants with disabilities and offer consultations during the selection process to ensure individual needs are taken into account. We value our collegial and family-friendly working environment, and offer excellent health insurance, pension contributions, flexible hybrid working arrangements, family allowances, diverse training opportunities and other social benefits. Salaries and allowances offered to ARISE2 fellows are competitive. The entry-level gross salary (excluding employer’s social contributions) varies by EMBL host site and currently ranges from 3291,23 to 4118,45 EUR per month. EMBL fellows are exempt from national taxes due to EMBL’s intergovernmental status, but contribute to EMBL’s social security system. A full overview of salaries at the different EMBL sites is available here. Our working language is English.

What else you need to know You will need to select the group you wish to join and prepare the short project proposal which you would like to do in the group. We strongly encourage you to contact the groups before applying, to inform them about your interest and learn about their future plans. For details on how to apply, please visit our ARISE2 website. The application with all required documents should be submitted using the online submission system. • We accept applications from 30 June - 30 September, 2026. • Interviews of top candidates are planned for November 25-27th, 2026 . • Start of the fellowship: between January and April, 2027. Please contact the ARISE2 team (arise2@embl.org) if you have any questions. EMBL is a signatory of DORA. Find out how we implement best practices in research assessment in our recruitment processes here Please apply online through: www.embl.org/jobs

Open position for a postdoctoral fellow in the Spaulding Lab at the Mount Desert Island Biological Laboratory in Bar Harbor, Maine. The Spaulding Lab uses C. elegans to investigate mechanisms and functions of subcellular organization, with a particular focus on the nucleolus. We are especially interested in understanding how disrupted subcellular organization contributes to age-related forms of neurodegenerative disease.

Works independently with full technical authority to direct electron microscopy core-facility operations. Serves as the institutional subject-matter expert for electron-microscopy methods, instrumentation, and workflows. Establishes facility-wide technical standards, oversees advanced research and clinical EM services, and ensures alignment with institutional research priorities. Serves as the core facility authority for electron microscopy services. Operates fully independently to manage instrument suites, develop facility-wide protocols, and drive innovation in sample preparation and imaging. Provides strategic technical consultation to internal and external stakeholders, ensuring the core meets both research and clinical objectives.  The Electron Microscopy Core Facility at UT Southwestern Medical Center is seeking a Chief Electron Microscopy Technician to support and oversee advanced electron microscopy operations within a dynamic, research-focused core facility.

SenseAI Vision is a disruptive software company in the electron microscopy market. It has proprietary ‘compressed sensing’ software that can generate better quality images with less data, to reduce beam damage and speed up workflows. It has applications outside electron microscopy as well. It is growing quickly and already has pedigree, publications and customers all over the world. We are seeking an entrepreneurial and results-driven Applications Engineer, to play a key role in the translation, adoption and growth of SenseAI’s technology into the electron microscopy market and indeed into new markets. What We Offer:

• Hybrid working – flexibility to work from home with regular in-person collaboration
• Monthly team meetups in Liverpool – stay connected with a motivated, passionate team
• Autonomy & opportunity – a genuine chance to shape the direction of a pioneering deep-tech start-up, with real responsibility from day one
• Competitive salary – commensurate with experience
• Options package – share in the success you help create
• Be part of something exciting – join a fast-growing, award-winning team working at the cutting edge of electron microscopy and beyond

  Responsibilities:

• Serve as primary technical liaison between customers and the product development team
• Provide expert-level application support for electron microscopy software, including installation, configuration, and troubleshooting
• Conduct product demonstrations, technical trainings, and workshops for customers, both onsite and remotely
• Collaborate with R&D to translate customer feedback into software improvements and new feature requirements
• Assist in the development of technical documentation, user guides, and training materials
• Support sales teams with technical expertise during pre-sales consultations and product evaluations
• Analyse customer workflows and recommend optimised solutions leveraging company software
• Test new software releases to ensure functionality, performance, and compatibility with various microscopy systems
• Participate in scientific conferences, workshops, and trade shows to showcase applications and engage with the research community
• Maintain up-to-date knowledge of electron microscopy techniques, imaging modalities, and related hardware/software integrations

  Preferred Qualifications:

  Essential:

• Right to work in the UK (essential) - candidates must hold or be eligible for full UK right to work;
• Based in, or willing to relocate to, the North West of England (preferred); UK-based candidates will also be considered
• Master's or PhD in Physics, Materials Science, Engineering, Biology, or related field
• Electron microscopy experience including TEM, STEM, SEM, and FIB-SEM
• Python and typical image processing workflows utilised in electron microscopy
• Experience solving problems related to implementing and further developing complex techniques
• Strong communication and presentation skills, comfortable working directly with scientists and engineers
• Strong knowledge of imaging analysis software, microscopy workflows, and data management
• Ability to travel to customer sites, conferences, and training events (up to ~30%) Desirable:
• Capable of operating a variety of instruments from various manufacturers, including detailed knowledge of internal and external hardware
• Knowledge or awareness of compressed sensing as applied to various EM techniques
• Experience working in materials science or life sciences using electron microscopy

SUMMARY Works independently with full technical authority to direct electron microscopy core-facility operations. Serves as the institutional subject-matter expert for electron-microscopy methods, instrumentation, and workflows. Establishes facility-wide technical standards, oversees advanced research and clinical EM services, and ensures alignment with institutional research priorities. Serves as the core facility authority for electron microscopy services. Operates fully independently to manage instrument suites, develop facility-wide protocols, and drive innovation in sample preparation and imaging. Provides strategic technical consultation to internal and external stakeholders, ensuring the core meets both research and clinical objectives. 

The Electron Microscopy Core Facility at UT Southwestern Medical Center is seeking a Chief Electron Microscopy Technician to support and oversee advanced electron microscopy operations within a dynamic, research-focused core facility.

The EMCF provides high-quality electron microscopy services to investigators across UT Southwestern, including transmission electron microscopy of cells and tissues, whole-mount scanning electron microscopy, negative staining, correlative light and electron microscopy, immunogold labeling, high-pressure freezing, freeze substitution, array tomography, and volume EM imaging. The facility supports a broad range of biological and biomedical research projects using advanced EM platforms and sample-preparation workflows.

The Chief Electron Microscopy Technician will play a key role in the daily operation, technical development, and user support activities of the Electron Microscopy Core Facility. The successful candidate will work with researchers to prepare samples, acquire high-quality EM data, troubleshoot technical issues, maintain instrumentation, and train users in EM-related workflows. This position is ideal for an experienced electron microscopy professional with strong technical skills, excellent organizational ability, and a commitment to supporting innovative biomedical research.

The Electron Microscopy Core Facility at UT Southwestern Medical Center is entering an exciting stage of growth and innovation. As a central research resource, EMCF partners with investigators across the institution to provide expert electron microscopy support, from project planning and sample preparation to high-resolution imaging, training, and data acquisition.

Our Core supports a wide range of biological EM applications, including TEM of cells and tissues, SEM of whole-mount samples, negative staining of macromolecules and microorganisms, correlative light and electron microscopy, immunogold labeling, high-pressure freezing, freeze substitution, array tomography, and volume EM. We are actively expanding our instrumentation and technical capabilities. The recent addition of the Thermo Scientific Hydra Bio Plasma FIB-SEM brings powerful new opportunities for volume EM, plasma FIB milling, correlative imaging, and advanced biological sample analysis. A new JEOL 120 kV JEM-120i TEM is also coming soon, further strengthening our TEM capacity and supporting the continued growth of the Core.

Joining EMCF means becoming part of a collaborative, research-driven environment where technical excellence directly supports scientific discovery. The selected candidate will have the opportunity to work with advanced electron microscopy platforms, contribute to the development of new workflows, support investigators across diverse research areas, and play an important role in the continued growth of one of UT Southwestern’s key research core facilities. For more information about the Electron Microscopy Core Facility, visit the EMCF website.

Key Responsibilities · Perform and oversee electron microscopy sample preparation for TEM, SEM, negative staining, immunolabeling, CLEM, and volume EM projects. · Operate and support advanced EM instrumentation, including TEM, SEM, FIB-SEM, high-pressure freezing, freeze substitution, ultramicrotomy, coating, and critical-point drying systems. · Support imaging workflows using instruments such as FEI Tecnai G2 Spirit BioTwin, JEOL 1400 Plus, Zeiss Sigma VP, and Thermo Scientific Hydra Bio Plasma FIB-SEM. · Train and assist researchers in TEM operation, SEM operation, sample processing, and negative staining workflows. · Coordinate project workflow, sample intake, scheduling, and communication with facility users. · Troubleshoot sample-preparation and imaging problems and recommend appropriate EM approaches for research questions. · Help maintain facility protocols, quality standards, equipment readiness, and safe laboratory practices. · Contribute to the continued growth of advanced EM capabilities, including volume EM, CLEM, high-pressure freezing, and immunogold labeling.

Preferred Qualifications · Strong hands-on experience with biological electron microscopy. · Experience with TEM and/or SEM sample preparation and imaging. · Knowledge of ultramicrotomy, resin embedding, negative staining, immunogold labeling, high-pressure freezing, freeze substitution, or volume EM. · Ability to work collaboratively with researchers from diverse scientific backgrounds. · Strong communication, documentation, organization, and troubleshooting skills. · Prior experience in a core facility, academic research environment, or biomedical imaging facility is highly desirable.

BENEFITS UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:

PPO medical plan, available day one at no cost for full-time employee-only coverage 100% coverage for preventive healthcare-no copay Paid Time Off, available day one Retirement Programs through the Teacher Retirement System of Texas (TRS) Paid Parental Leave Benefit Wellness programs Tuition Reimbursement Public Service Loan Forgiveness (PSLF) Qualified Employer Learn more about these and other UTSW employee benefits!(Opens in a new window) EXPERIENCE AND EDUCATION

Required

Education Master’s Degree in a relevant scientific, engineering, or biomedical field or  Bachelor’s Degree in a relevant scientific, engineering, or biomedical field    Experience 3 years of progressively responsible electron microscopy experience, demonstrating increasing leadership over EM operations, instrumentation, and service delivery with a Master’s Degree or  5 years of progressively responsible electron microscopy experience, demonstrating increasing leadership over EM operations, instrumentation, and service delivery with a Bachelor’s Degree 

The Center for Bioimage Informatics at St. Jude Children's Research Hospital is seeking two Senior Image Data Scientists to design, develop, validate, document, and operate image-analysis pipelines and visualization solutions for biomedical imaging research. This role works closely with investigators, software engineers, data scientists, imaging facility scientists, and biostatisticians to translate scientific questions into reproducible, scalable analysis workflows using modern image analysis, statistical, computer vision, and machine learning approacheThe successful candidate will support image data management, maintain analysis software and repositories, evaluate new methods and tools, and provide technical consultation and training to research teams. This role also serves as a project lead to coordinate image-analysis efforts, align related projects, and contribute to shared CBI infrastructure that supports routine and advanced bioimage analysis. 

Applicant Statement:  Applicants are encouraged to include a brief cover letter or supplemental statement with a link to representative work, such as a public repository, napari plugin, published pipeline, or comparable artifact. The statement should briefly describe one end-to-end image-analysis project or software tool the applicant has owned in production, including the biological or scientific question, data scale, methods or model used, pipeline design, validation approach, user adoption, and resulting impact. 

Preferred Qualifications: 

• PhD in a relevant quantitative, computational, biomedical, or scientific field. 
• Experience developing, validating, and maintaining image-analysis pipelines for biological or medical imaging data. 
• Strong programming skills in Python and experience with modern computer vision, machine learning, deep learning, or statistical image-analysis methods. 
• Experience with emerging AI methods relevant to bioimage analysis, including vision transformers, foundation models, generative AI, large language models (LLMs), or agentic AI tools. 
• Experience with scalable and reproducible scientific workflows (e.g., Snakemake, Nextflow), containers, version control, and HPC or cloud environments. 
• Demonstrated experience using modern bioimaging tools, data standards, and open-source ecosystems such as napari, ImageJ/Fiji, Cellpose, SAM-family and related foundation segmentation models, QuPath, BioFormats, OME-Zarr/NGFF, or similar platforms. 
• Experience with large image data volumes, image data management, quality control, benchmarking, annotation strategies, and method evaluation. 
• Demonstrated ability to collaborate with research teams, communicate technical results clearly, write user-facing documentation, and provide training through courses, workshops, seminars, or similar formats. 
• Evidence of technical leadership, such as leading multi-lab projects, contributing to shared infrastructure, publishing methods, or contributing to open-source scientific software. Minimum Education and/or Training:
• Bachelor's degree in applied mathematics, physics, chemistry, bioinformatics, computer science, data science, computer engineering or related field required.
• Master's degree preferred.

Minimum Experience:

• Minimum Requirement: Bachelor's degree with 3+ years of work experience in relevant area (e.g., applied mathematics, physics, chemistry, bioinformatics, computer science, data science, computer engineering) required.
• Experience Exception: Master's degree with 1+ years of relevant experience.
• Experience in image analyses, image data management, and programming (e.g., Python, R, Matlab, Java, C/C++).
• Experience in image analysis platforms (e.g., ImageJ/Fiji, CellProfiler), scientific computing, scientific data visualization, scientific computer code optimization and evaluation in an HPC environment, development of algorithms, statistical methods or scientific software, working with large image data volumes, biological/medical imaging preferred.
• Proven performance in earlier role/comparable role.

Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Senior Image Data Scientist-Center for Bioimage Informatics.

Explore our exceptional benefits!

St. Jude is an Equal Opportunity Employer

No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

The laboratory of Dr. Xing Liu in the Department of Biochemistry at Purdue University is seeking highly motivated Postdoctoral Researcher to join an interdisciplinary and mechanistic research program. More details can be found here: https://jobrxiv.org/job/purdue-university-27778-postdoctoral-researcher-biochemistry-and-cell-biology/

Advanced Workflow Specialists Manager

Leica Microsystems  Cassina De' Pecchi, Milano, Italy  Category Customer Support Job Id R1310698 This job available in 6 locations 

Next job  Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology? At Leica Microsystems, one of Danaher’s 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact.  You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact – innovating at the speed of life. Shape the Future with Us! At Leica Microsystems, we have been shaping the future for over 175 years with groundbreaking optical and digital solutions. With a culture rooted in customer focus, innovation, and teamwork, we lead the market in microscopy, imaging, and analysis, unveiling the invisible and empowering our customers to build a better, healthier world. Joining Leica Microsystems means contributing to scientific discoveries and supporting surgeons in making critical decisions. Our advanced microscopes and AI-based image analysis solutions enable users to gain profound insights into development and engineering challenges. Here, you will work on meaningful projects alongside passionate colleagues, driving progress and pushing the boundaries of what’s possible. Learn about the Danaher Business System which makes everything possible. The Application Workflow Specialists Manager(d/f/m) is responsible for leading a team of Advanced Workflow Specialists with the aim of making best use of the available resources and developing them according to the market demands. Supporting the area on Scientific and Application requests requiring advanced knowledge and expertise to maximize sales revenue. This role is key to enable the delivery of custom-tailored value propositions throughout all our touch points along the customer journey to increase our win rate, revenues and market share through the AWS team. This position reports to the Director Business Development EMEA and is part of the Business Development Team working remotely to cover EMEA.  In this role, you will have the opportunity to:

• Develop and enable the AWS team to support and guide the sales force in demonstrating value propositions through best-in-class demonstrations, application support, product knowledge to grow revenues
• Contributes to the development of accounts through speeding up customer onboarding and drive positive customer advocacy
• Provide Market Intelligence: market trends, new applications, technologies, analysis workflows, competition and customer needs. Support the development of targeted application notes.
• Contribute to translating the strategy at EMEA regional level into actions
• Monitor execution of action plans and course correct as appropriate to achieve desired results
• Proactively support the development of direct reports and associates through quality career discussions and lived development plans. Support new hires integration through carefully designed immersion plans as well as through training and mentoring
• Engage actively and collaborate closely with Sales and Marketing and drive team Engagement and foster an inclusive culture. The essential requirements of the job include:
• Minimum 4 years of hands-on experience in the field of Life Science microscopy.
• Profound knowledge of 3D imaging solutions and Image analysis
• Experience in Biopharma and Biotech environments
• First-hand knowledge of applied microscopy solutions are a plus
• Sales talent and knowledge about sales or proven sales experience is a plus Travel, Motor Vehicle Record & Physical/Environment Requirements: i
• Ability to travel – 50%
• Must have a valid driver’s license with an acceptable driving record It would be a plus if you also possess previous experience in:
• Selling Capital Equipment into the Academic and (Bio-)Pharmaceutical Market Leica Microsystems, a Danaher operating company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it’s a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at Danaher Benefits Info. At Leica Microsystems we believe in designing a better, more sustainable workforce. We recognize the benefits of flexible, remote working arrangements for eligible roles and are committed to providing enriching careers, no matter the work arrangement. This position is eligible for a remote work arrangement in which you can work remotely from your home. Additional information about this remote work arrangement will be provided by your interview team. Explore the flexibility and challenge that working for Leica Microsystems can provide. LI-EB1 Donnez vie à votre potentiel Êtes-vous prêt(e) à accélérer votre potentiel et à avoir un impact réel dans les sciences de la vie, le diagnostic et les biotechnologies ? Chez Leica Microsystems, l’une des plus de 15 sociétés opérationnelles de Danaher, notre travail sauve des vies — et nous sommes tous unis par un engagement commun à innover pour un impact concret. Vous vous épanouirez dans une culture d’appartenance où votre point de vue unique compte. En exploitant le système d’amélioration continue de Danaher, vous contribuerez à transformer les idées en impact — en innovant à la vitesse de la vie. Façonnez l’avenir avec nous ! Chez Leica Microsystems, nous façonnons l’avenir depuis plus de 175 ans grâce à des solutions optiques et numériques révolutionnaires. Avec une culture ancrée dans l’orientation client, l’innovation et le travail d’équipe, nous sommes leaders du marché en microscopie, imagerie et analyse, révélant l’invisible et permettant à nos clients de construire un monde meilleur et plus sain. Rejoindre Leica Microsystems, c’est contribuer à des découvertes scientifiques et aider les chirurgiens à prendre des décisions critiques. Nos microscopes avancés et nos solutions d’analyse d’images basées sur l’intelligence artificielle permettent d’obtenir des insights précieux face aux défis du développement et de l’ingénierie. Ici, vous travaillerez sur des projets porteurs de sens aux côtés de collègues passionnés, en accélérant le progrès et en repoussant les limites du possible. Découvrez le Danaher Business System, qui rend tout cela possible Le/la Responsable des spécialistes des workflows applicatifs (Application Workflow Specialists Manager - d/f/m) est chargé(e) de diriger une équipe de spécialistes des workflows avancés afin d’optimiser l’utilisation des ressources disponibles et de développer les compétences en fonction des besoins du marché. Il/elle soutient la région sur les demandes scientifiques et applicatives nécessitant un haut niveau d’expertise, dans le but de maximiser le chiffre d'affaires. Ce rôle est essentiel pour permettre la mise en œuvre de propositions de valeur personnalisées à chaque point de contact du parcours client, afin d’augmenter notre taux de succès, nos revenus et notre part de marché grâce à l’équipe AWS. Ce poste est rattaché au Directeur Business Development EMEA et fait partie de l’équipe Business Development, avec une couverture EMEA en remote. Dans ce rôle, vous aurez l’opportunité de :
• Développer et accompagner l’équipe AWS pour soutenir les équipes commerciales dans la démonstration de propositions de valeur via des démonstrations de premier niveau, du support applicatif et une expertise produit afin de stimuler la croissance du chiffre d’affaires
• Contribuer au développement des comptes en accélérant l’onboarding client et en favorisant une expérience client positive
• Fournir des informations de marché : tendances, nouvelles applications, technologies, workflows d’analyse, concurrence et besoins clients, et contribuer au développement de notes applicatives ciblées
• Participer à la déclinaison de la stratégie EMEA en actions concrètes
• Suivre l’exécution des plans d’action et ajuster si nécessaire pour atteindre les résultats attendus
• Soutenir activement le développement des collaborateurs via des discussions de carrière de qualité et des plans de développement concrets, ainsi que l’intégration des nouveaux employés via des parcours d’immersion et du mentoring
• Collaborer étroitement avec les équipes Sales et Marketing, encourager l’engagement et promouvoir une culture inclusive Profil recherché
• Minimum 4 ans d’expérience pratique en microscopie appliquée aux sciences de la vie
• Excellente connaissance des solutions d’imagerie 3D et d’analyse d’images
• Expérience dans les environnements biopharma ou biotech
• Connaissance pratique des solutions de microscopie (atout)
• Expérience ou affinité avec les ventes (atout) Mobilité et exigences
• Capacité à voyager jusqu’à 50 %
• Permis de conduire valide requis Un plus si vous avez également :
• Une expérience dans la vente d’équipements de capital auprès d’institutions académiques ou du secteur (bio)pharmaceutique Avantages & environnement de travail Leica Microsystems, société du groupe Danaher, propose un large éventail de programmes d’avantages compétitifs qui enrichissent notre quotidien. Qu’il s’agisse de programmes de santé ou de congés payés, nos bénéfices contribuent à une vie équilibrée au-delà du travail. Chez Leica Microsystems, nous croyons en une organisation du travail durable et flexible. Pour les rôles éligibles, nous offrons la possibilité de travailler en remote. Ce poste permet un mode de travail à distance depuis votre domicile. Découvrez la flexibilité et les défis qu’offre une carrière chez Leica Microsystems. Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life. For more information, visit www.danaher.com.

The Biomedical Optical Imaging Laboratory at the University of Illinois Urbana-Champaign invites applications for a postdoctoral associate to lead biologically driven research in spatial biology, cancer biology, and translational imaging. Our laboratory develops and applies advanced optical imaging technologies, including multiplexed fluorescence imaging, super-resolution microscopy, quantitative phase imaging, and spatial image analysis, to study cancer biology across molecular, cellular, and tissue scales. A central goal of our work is to transform advanced imaging technologies into practical tools for disease diagnosis, treatment response assessment, risk stratification and precision medicine. For more information, please visit our website: This position is designed for a motivated scientist with a strong background in cancer biology, molecular biology, cell biology, chromatin biology, epigenetics, immunology, pathology, or related fields. The postdoctoral associate will investigate how cancer cells and their microenvironments change during tumor progression, treatment response, recurrence, and clinical disease evolution. Potential research directions include cell-state plasticity, tumor heterogeneity, chromatin and nuclear organization, epigenetic regulation, tumor–immune interactions, tissue architecture, and spatial biomarkers for clinical translation. The successful candidate will join a multidisciplinary team of biologists, engineers, imaging scientists, computational scientists, pathologists, clinicians, and translational partners. The position provides strong opportunities for high-impact publications, biological discovery, grant writing, conference presentations, mentoring, translational research, technology development, and exposure to commercialization pathways. Candidates interested in moving discoveries toward clinical implementation, diagnostic applications, biotechnology, or startup translation are especially encouraged to apply.

Responsibilities The postdoctoral associate will lead biologically motivated studies using advanced spatial imaging approaches. Responsibilities include: · Develop, optimize, and execute multiplexed immunofluorescence staining workflows in cells, 3D cultures, organoids, spheroids, and tissue sections. · Design and perform experiments to investigate cancer progression, treatment response, tumor heterogeneity, cell-state plasticity, and microenvironmental organization. · Study changes in chromatin organization, epigenetic regulation, nuclear morphology, DNA damage response, proliferation, senescence, differentiation, and cellular adaptation in cancer models. · Apply complementary biological approaches, including 2D/3D culture systems, tissue-based studies, molecular biology assays, and functional perturbation experiments, to support imaging-based discoveries. · Integrate multiplexed fluorescence imaging, super-resolution microscopy, quantitative phase imaging, and quantitative image analysis to connect cellular morphodynamics with molecular and functional states. · Work closely with computational team members to analyze spatial and single-cell imaging data and extract biologically meaningful insights. · Prepare manuscripts, present findings at conferences, contribute to grant applications, and mentor graduate and undergraduate trainees.

Qualifications Applicants should have, or be close to completing, a Ph.D. in bioengineering, biophysics, biotechnology, cancer biology, cell biology, biomedical sciences, immunology, pathology, or a related discipline. The successful candidate must have hands-on proficiency in multiplexed immunofluorescence staining and fluorescence microscopy, with experience applying these methods to biological questions in cancer, immunology, epigenetics, or related fields. Hands-on experience with spatial omics, super-resolution microscopy, expansion microscopy, tissue clearing, advanced image analysis, or translational cancer studies is desirable. Strong candidates should have relevant experience in one or more of the following areas: · Highly multiplexed fluorescence imaging, spatial biology, confocal microscopy, super-resolution microscopy, or quantitative microscopy · 2D/3D cancer models, organoids, spheroids, tissue sections, patient-derived samples, or molecular biology assays · Cancer biology, tumor progression, drug screening, tumor microenvironment biology, or cancer cell plasticity · Chromatin biology, epigenetic regulation, nuclear organization, DNA damage response, or transcriptional regulation · Quantitative image analysis using ImageJ/Fiji, Python, MATLAB, CellProfiler, or related tools

We are especially interested in candidates with a demonstrated track record of independent research, strong problem-solving ability, rigorous experimental design, careful troubleshooting, attention to detail, and scientific creativity. The ideal candidate should be able to formulate meaningful biological questions, design and execute experiments, optimize staining and imaging workflows, interpret complex spatial imaging data, communicate findings clearly, and take intellectual ownership of a project. The Postdoctoral Research Associate is a full-time, benefits-eligible position appointed on a 12-month service basis. The initial appointment is for one year with the possibility of extension based on performance and funding. The anticipated start date is as soon as possible, but negotiable. Salary is commensurate with experience and qualifications. Applicants should send a cover letter, CV, and the names and contact information of three references to Prof. Yang Liu by email (liuy46@illinois.edu). Applications will be accepted until the position is filled.  The University of Illinois System is an equal opportunity employer, including but not limited to disability and/or veteran status, and complies with all applicable state and federal employment mandates.  Please visit Required Employment Notices and Posters to view our non-discrimination statement and find additional information about required background checks, sexual harassment/misconduct disclosures, and employment eligibility review through E-Verify.

The main purpose of this job is to bring cutting-edge light microscopy research approaches to Brandeis researchers and oversee the day-to-day operations of the Brandeis light microscopy facility. The employee will supervise and maintain several $1M+ instruments and associated computers. They will conceptualize, design, run, and analyze novel experiments with users in the light microscopy facility, and train and oversee users running the microscopes. They will manage projects, author papers and will write equipment grants as co-principal investigator. The employee will interface with service engineers and other relevant Brandeis staff (e.g. facilities, finance, procurement). The employee will manage procurement, billing, scheduling, and finances of the facility. They will also do all the administrative and organizational work for the facility, manage compliance and the budget, and oversee others with less experience. The employee will serve as the sole liaison to outside academic and industry users of the facility. Job Description:

• Maintains light microscopes and ancillary equipment and computers. Calls for service when needed and negotiates/selects service agreements. Decides on and executing needed maintenance and repairs. Maintains organization and safety of light microscopy facility, interfaces with facilities for maintenance of light microscopy facility. 25%
• Trains users on light microscopes and ancillary equipment and computers. Conceptualizes and oversees a wide range of complex, novel experiments and data analyses. Supports and advises trained users on a daily basis on their projects, including data acquisition and analysis. Devises optimal approaches to meet scope of work and ensure timely high quality submissions and deliverables. May be co-author on publications and contribute to writing. 25%
• Administers the light microscopy facility, including budget management, billing, user agreements, ordering lab supplies, coordinating with financial staff on periodic reports, website updates and maintenance. Serves as the sole liaison to outside academic and industry users of the facility. 10%
• Plans acquisition or assembly of new high-end instruments, or upgrades of existing instruments. Contributes to writing equipment grants, including as co-PI 10%
• Coordinates and meets regularly with light microscopy facility faculty co-directors. 5%
• Lead workshops on microscopy and image analysis for undergraduates, graduate students, postdocs, and staff 5%
• Serves as liaison to light microscopy experts in the wider scientific community. Attends national and international meetings to stay abreast of the latest technology. 5%
• May teach a lecture or lab-based 2- or 4-credit course 15% The salary range for the position is $82.2k-$100k. Job Description:
• Bachelor's degree (life sciences or physical sciences) is reuired. Doctoral degree is preferred.
• Must have 5 or more years experience with Light Microscopy experiments, equipment maintenance, and data analysis including widefield, confocal microscopy super-resolution (e.g., STED), and lightsheet microscopy.
• Previous experience in facility management is greatly desired.
• Will support experiments for 20 or more different user groups from Brandeis, outside academic institutions, and industry. Responsibility for light microscopy facility budget ($100000+/year range). Collaborates with facility directors in writing 1-2 grants/year

The Inserm chair recruitments are Tenure Tracks intended for researchers with strong potential to manage and lead research teams and participate in national, European or international projects.

Scientific project: Development of nano-imaging methods for complex patho-physiological processes monitoring Understanding many complex diseases and designing rational treatments requires research on multiple scales, ranging from molecular events to morphological and functional behaviour at the organ level. The dynamics and spatial organization of signalling pathways can be essential in determining normal or pathological responses in cells and tissues. This project aims to provide a versatile toolkit for precision imaging at the nanometre scale and with sub-second resolution, compatible with complex systems. This approach will be applied in vitro to study the spatiotemporal organization of fundamental biological functions (division, transcription, trafficking, etc.) in single-celled organisms in various contexts, providing a new test for relevant biomedical questions, such as stress response or antibiotic resistance.

Summary of the teaching project: The junior professor is expected to teach and train students at École Polytechnique/Institut Polytechnique de Paris, either at the master's level or at the bachelor's level and in the École Polytechnique engineering program. He/she expected to teach biology, biomedical engineering, biophotonics or biophysics for a minimum of 42 hours per year, with the possibility of teaching up to 64 hours per year for an additional salary. He/she will also benefit from an environment conducive to innovation, with the local Drahi-X innovation centre and local initiatives aimed at supporting technology transfer.

Strategy of the host institution: The French National Institute for Health and Medical Research (Inserm) is the primary public institution dedicated to biomedical and health research. Inserm conducts research with a focus on translating research findings into clinical and therapeutic applications that address current public health challenges. Partners include universities, hospitals, and international research organizations. École Polytechnique is a leading French institute within the Institut Polytechnique de Paris and part of the dynamic Saclay scientific hub, combining high-level research, teaching, and innovation at the cutting edge of science and technology. The research conducted covers all modern scientific fields, with the aim of providing answers to today's major societal challenges. Among these fields, the theme of “Biology-Health” has seen significant development in recent years, with the creation of a highly active interdisciplinary center called “Engineering for Health (E4H)”. Supported by the ExcellenceS (France2030) “STEP2” project, the center will be joined by several junior professors. The researcher recruited in this program will strengthen the Laboratory for Optics and Biosciences, a leading laboratory in the “Biology-Health” theme at the Institut Polytechnique de Paris and participate in this major movement for the Life Sciences.

Strategy of the host laboratory: The junior professor will join the Laboratory for Optics and Biosciences (LOB, https://lob.ip-paris.fr/en), a joint Inserm-CNRS Physics-École Polytechnique unit. The LOB recently received a very positive evaluation from HCERES and Inserm, and the unit has been renewed in January 2026. The LOB is part of a dynamic environment within the interdisciplinary Engineering for Health (E4H) centre, which brings together fundamental, technological, and computational activities for health sciences in the laboratories and facilities of Institut Polytechnique de Paris. The junior professor will strengthen the “Quantitative Nanoimaging of Biological Systems – Organization and Dynamics” team, https://lob.ip-paris.fr/en/research/nanoimaging-cell-dynamics-and-quantitative-biology, which focuses on cell signalling processes and develops original techniques based on tracking single molecules using fluorescent nanoparticles or super-resolution.

Intelligent Imaging Innovations (3i) Ltd is looking for a Technical Support Specialist to join its expanding team in London, England. 

The ideal candidate has earned a bachelor's or technical degree and has experience with optics. Familiarity with multiphoton, confocal, imaging analysis, advanced microscopy and/or fluorescent microscopy is highly preferred. 

We are hiring a postdoctoral fellow to develop high speed voltage imaging technology. We have developed an approach to capture fluorescence lifetime images at kilohertz frame rates, opening several exciting directions for quantitative measurements in the brain. Our work is interdisciplinary by nature, and candidates may come from many different backgrounds including neuroscience, engineering, physics, and bioengineering.

As the BioOptics Core Facility expands its portfolio, we are seeking a microscopy specialist with focus on multiphoton intravital microscopy who will both establish this specialized modality and strengthen our core team's expertise across the facility's comprehensive range of advanced imaging techniques. The BioOptics Core Facility supports an international community of 36 research groups and 450 scientists at the IMP, IMBA, and GMI as well as scientists from the Vienna BioCenter and beyond. We provide expert services in flow cytometry, microscopy, and image analysis, utilizing state-of-the-art instrumentation and advanced software. Explore our capabilities at: http://cores.imp.ac.at/biooptics/ 

Key responsibilities

• Establish and integrate our new commercial multiphoton intravital microscopy system into the facility's workflow
• Provide comprehensive user support for MP-IVM applications, from initial consultation through data acquisition
• Design and innovate custom sample holders, accessories, and workflows that enable seamless exchange between specimen types and experimental approaches
• Support experimental design by working closely with researchers to translate biological questions into optimized imaging strategies
• Expand the microscopy team's expertise by offering training and support across the facility's diverse portfolio of advanced imaging techniques and assisting with instrument maintenance

  Key requirements

• Strong background in Biophysics or any related field
• Thorough knowledge and understanding of advanced microscopy technologies
• Expertise and practical experience in multiphoton intravital microscopy
• Passion for technology development and innovation
• Self-organized, structured, and reliable working style within a team environment
• Excellent command of English (spoken and written) is required; German skills are an asset
• Enthusiastic, friendly, collaborative mindset and the ability to interact professionally with facility users

  What we offer

  The institutes, embedded in the Vienna Biocenter (VBC), are offering the opportunity to work in a dynamic international environment with excellent benefits including child support center, subsidized cafeteria, and training courses. The yearly gross salary starts from € 68.000,- depending on qualification and experience. 

The position is open immediately and is initially limited to one year with a strong intention to extend. Please send your comprehensive CV, a detailed letter of motivation and references (including current contact details of two referees) using the portal below:

https://imba.onlyfy.jobs/application/apply/69sth8yiurd25atenx80zxx4kko0v8l

GMI - Gregor Mendel Institut für Pflanzenbiologie GmbH www.imp.ac.at; www.imba.oeaw.ac.at; www.gmi.oeaw.ac.at; www.viennabiocenter.org; BioOptics homepage 

The Bisson Lab at Indiana University Bloomington is hiring a research engineer to build the imaging and environmental hardware for a new project on microbial life in the Great Salt Lake. We study how archaea and other halophiles sense and respond to mechanical and physicochemical forces. To do this in situ, we are building portable microscopes, microfluidic devices, and synthetic Great Salt Lake (SynGSL) tank systems housed in IU's greenhouse. This is a hands-on instrument-building role — design through iteration, not delivery to spec.

You will

• Build and field-deploy portable optical microscopes for live imaging of ~1 µm cells in brine and salt-crystal environments.
• Design and construct greenhouse-scale environmental tanks with optical access for long-term live imaging.
• Develop microfluidic devices (PDMS, fluoropolymers, brine-compatible materials) for confined-flow experiments.
• Travel to the Great Salt Lake (1–4 trips/year) to test and iterate equipment in the field.
• VMLs classification correlating microbiome community images and metagenomic data Profile we want
• Hands-on experience building scientific instruments — optics, mechanics, electronics, fluidics, or any combination. Demonstrated builds matter more than degrees.
• Comfort moving between machine shop, optics bench, and wet lab.
• Comfort with ambiguity in early-stage projects where the spec evolves with the science.
• Willing to live with what you build for 1–3 years and rebuild it when it fails. Bonus: microfluidics/soft lithography, environmental rigs, 3D-printing/CAD, embedded control (Arduino/RPi), Python.

Required BS or higher in engineering, physics, or related field desired — but not required as long equivalent demonstrated build experience. PhD not required.

Logistics

• Full-time, IU Bloomington. On-site (lab + greenhouse).
• Initial 1-year appointment, renewable. Funding in place.
• Salary commensurate with experience, IU research staff scales.
• Start: summer 2026 onwards To apply Send a one-page cover letter (focus on what you've built), CV, and contact info for 2 references to saltylab@iu.edu with subject line "SynGSL Engineer — [Last Name]". Rolling review, position open until filled. Lab: bissonlab.com Blurb of the position at LinkedIn: https://shorturl.at/mosz7 Indiana University is an equal opportunity employer.

The position We are looking for strong and motivated candidate to fill one postdoc position or one IR position (both 1 year renewable, multi-year funding) in the group ‘Physics and mechanics of biological systems’ at CBS Montpellier, France. Our project probes the physics of bacterial motility and biofilm formation from an experimental biophysics perspective.

Activities • digital inline holography and computational reconstruction of holograms • light sheet microscopy, TIRF microscopy, fluorescent microscopy • microscope design and construction • machine learning, artificial intelligence • image analysis, time series analysis • single-molecule biophysics • programming • wetlab activities and cell/molecular biology (bacteria)

Expertise sought We seek an outstanding candidate who has (or will soon have) a PhD and who: • has a strong background in physics, optics, biophysics, or a related discipline; • has experience or is intimately familiar with digital holography and numerical reconstruction of holograms; • has experience or is intimately familiar with light sheet microscopy or TIRF microscopy; • has experience in advanced microscope design and construction; • has experience or extensive knowledge in machine learning; • has experience with image analysis, time series analysis, and quantitative data analysis; • has experience with programming (our lab works primarily in Python); • either has experience in a wet lab, or is eager to learn to work with bacteria; • is innovative and enjoys troubleshooting and pushing the limits of custom optical microscopy setups; • enjoys working in an interdisciplinary environment; • is creative, enthusiastic, highly motivated, and able to work both independently and as a member of a team. High level English communication skills are an asset; no knowledge of French is required. We strive for gender and diversity equality, and we welcome applications from all backgrounds.

Context of the work Most our knowledge of bacteria comes from studies of independent swimming cells. Yet, most bacteria on earth are found in non-motile aggregated communities, called biofilms, which bear little resemblance to their motile counterparts. Biofilms are acutely resistant to antibiotics, extremely difficult to eradicate, and are implicated in important global challenges, from deadly infections and antimicrobial resistance to food safety and water security.

Under the current paradigm, biofilms begin when a motile cell adheres and senses a surface, triggering a change in ‘lifestyle’. But, this crucial nucleation step remains poorly understood: what mechanochemical signal underlies surface sensing? Moreover, many natural biofilms, including many that cause chronic infections, exist in absence of a substrate, suggesting that biofilms can nucleate via multiple mechanisms. Can nucleation be understood, not as a biochemical switch of an individual, but as an emergent behavior of active colloids?

By developing a unique setup which combines digital holographic microscopy and light sheet microscopy, this project seeks to capture and resolve rare nucleation events, and the resulting physiological response, thereby uncovering the physical mechanisms of biofilm initiation in various microenvironments.

This is a new project and new line of research led by a young PI, Ashley Nord, funded by the Foundation Bettencourt Shueller Impulscience award (for 5 years). Ashley is a part of the ‘Physics and Mechanics of Biological Systems’ team, comprised of three permanent CNRS researchers, all with a background in physics and biophysics. The team is highly interactive and dynamic, and the candidate will have the opportunity to collaborate on other ongoing projects within the team, depending on their interests. The Center for Structural Biology (CBS) is an interdisciplinary and international research institute located in Montpellier, France. It is comprised of 13 research teams with a mix of biophysics, bioengineering, and structural biology. Their expertise spans a vast range, including cutting-edge optical microscopy techniques, optical and magnetic tweezers, atomic force microscopy, NMR, X-ray crystallography, bioinformatics, bioengineering, and biomolecular modelling. It is home to many PhD students and postdocs of diverse backgrounds and nationalities.

Applications will be reviewed on a rolling basis until the position is filled.

This role oversees a state-of-the art service facility by performing a broad range of complex laboratory and research related assessments and self-evaluations, acting as a specialist on laboratory methods and equipment functions, performing a variety of tests requiring a high degree of proficiency, troubleshooting problems and recommending solutions, evaluating experiment results using complex statistical and multivariate analysis.

  Position Summary

• The primary role is to manage the day-to-day operations of the Integrated Biomedical Imaging Facility and the Translational Hearing Center Imaging Facilities, including several types of confocal and multiphoton microscopes, a tunable near-infrared laser, and advanced analytical software applications (such as Imaris).
• Additional responsibilities include maintaining instruments in excellent working order, performing regular quality assurance checks, interfacing with technical service personnel from the various vendors, conducting training sessions for new users and advising users on optimizing imaging protocols, keeping billing records, keeping current with the latest information in a rapidly developing field of research, generating monthly invoices, and providing customer assistance.
• Supported by multiple state and federally funded research grants (NIH, NE-INBRE, COBRE), this role requires active participation in organizational meetings and the development of progress reports, presentations, and future grant submissions. 
• Candidates with a terminal degree are eligible for a non-tenure track faculty appointment.
• Proficiency with imaging platforms from major vendors (including Nikon, Leica, Zeiss, and Molecular Devices) is essential. The instruments have multiple imaging capabilities and therefore selecting the appropriate instrument for a user's task is especially important.
• Additional responsibilities include maintaining instruments in excellent working order, performing regular quality assurance checks, interfacing with technical service personnel from the various vendors, conducting training sessions for new users (around 50 per year) advising users on optimizing imaging protocols; Providing customer assistance.
• Keep billing records and generating monthly invoices.
• Other duties as assigned; i.e keeping current new research and preparing information/data for grant submissions and reports.   Qualifications
• Master's degree in related field of science is required, PhD preferred.
• 6+ years of research lab experience.
• 6+ years of experience in optics and advanced microscopy techniques.
• Supervisory experience required.
• Experience in writing manuscripts and grant proposals.
• Advanced computer skills (editing code, analyzing data, creating graphics, image processing) and analytical skills needed.   This role is partially grant funded.  

  About Us

  Creighton University is committed to providing a safe and non-discriminatory educational and employment environment. The University admits qualified students, hires qualified employees and accepts patients for treatment without regard to race, color, religion, sex, marital status, national origin, age, disability, citizenship, sexual orientation, gender identity, gender expression, veteran status, or other status protected by law. Its education and employment policies, scholarship and loan programs, and other programs and activities, are administered without unlawful discrimination. Creighton complies with all applicable laws and regulations governing equal opportunity in the workplace and in educational activities.

Applicants with disabilities needing reasonable accommodations to complete the application or hiring process should contact Human Resources at HR@creighton.edu. Creighton University seeks candidates who understand, respect, and can contribute to the University's mission and values. 

Who We Are: Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science, academic and industry partners, and vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs. Position Description: The Cellular Models and Assay Technologies (CMAT) lab and Microscopy group at Calico are looking for an innovative, technology-driven Scientist to join our teams. This role offers a rare chance to push the boundaries of microscopy and spatial biology within a biotech environment, where novel technologies can be rapidly translated into biological insights that directly inform therapeutic strategy. In collaboration with Biology subject matter experts, the successful candidate will invent, adapt, and apply advanced microscopy techniques to unravel the mechanisms underlying age and age-related disease. A primary area of focus will be the integration of Laser Capture Microdissection (LCM) with proximity biotinylation, in order to map molecular environments within cells and tissues. By combining these with fluorescent biosensors and morphological profiling, you will aim to identify and isolate specific cellular states for deeper phenotyping.  This hands-on role requires deep expertise in Microscopy, Image Analysis, Cell and Tissue Biology, alongside the ability to develop or implement novel methods as needed. This role will evolve as scientific questions demand, and we are looking for a curious, versatile and proactive scientist who takes an active role in the evolution and expansion of their role.  Responsibilities:

• In collaboration with other Microscopy and Image Analysis experts, deploy cutting edge technologies to accelerate diverse projects across Calico
• Apply Laser Capture Microdissection (LCM) to isolate specific cell populations or morphological features from cell cultures and tissue sections for downstream multiomics analysis
• Accelerate LCM workflows through automated image analysis and segmentation
• Design and optimize functional reporters in cells and tissues, e.g. proximity biotinylation, to map protein-protein interactions, and fluorescent biosensors to track cellular response to perturbation
• Continuously explore this ever-evolving field and invent and/or implement novel systems as they become available Position Requirements:
• Ph.D. in Cell Biology, Bioengineering, Biophysics, or a related field with 3+ years of post-doctoral or industry experience
• Extensive hands-on experience with complex fluorescence microscopy techniques (e.g. laser capture microdissection, smart microscopy, light sheet, live cell imaging, super-resolution, etc.)
• Track record of developing or adapting novel microscopy methods to uncover biological insights
• Demonstrated ability in quantitative image analysis, utilizing commercial software (e.g., Imaris, Arivis), open-source tools (e.g., FIJI, CellProfiler), and custom solutions (e.g., Python)
• Experience with functional reporter systems in cells and/or tissues (e.g., proximity biotinylation, fluorescent biosensors) and demonstrated ability to rapidly adopt new techniques
• Experience with mammalian cell culture and stable cell line generation with a diversity of delivery systems
• Ability to operate independently, define experimental strategies, and prioritize multiple concurrent projects in a fast-paced environment
• Exceptional interpersonal and communication skills and effective collaboration across functional groups
• Must be willing to work onsite 5 days per week Nice to Have:
• Demonstrated proficiency in Laser Capture Microdissection (e.g. Leica LMD) applications in a diversity of cell and tissue types
• Hands-on experience with proximity biotinylation techniques (i.e. BioID, APEX2, TurboID, BAR), including antibody conjugation strategies, fusion protein design, labeling kinetics optimization, and streptavidin-based enrichment
• Hands-on experience with development, optimization, and application of fluorescent sensors and biosensors
• Familiarity with custom microscope hardware and control software
• Experience with complex cell culture models (e.g. primary culture, iPSC-derived neurons, microglia)
• Experience with multiplex immunofluorescence and histological techniques, including tissue processing (FFPE and OCT blocks), cryosectioning, human tissues and patient-derived samples The estimated base salary range for this role is $156,000 - $191,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.