Job Openings

We are looking for a highly motivated PhD student (f/m/d) in the field of materials science who is passionate about both physical chemistry and nanoscale characterization of materials. The PhD position is part of the E-MOSAIC project, which is focused on the development of electron microscopy approaches for the characterization of complex hybrid materials at the atomic scale. As a member of the project team, you will contribute to establishing and applying low-electron-dose workflows for the analysis of the local structure in soft functional materials (semi-crystalline and amorphous materials) using electron diffraction and electron energy loss spectroscopy methodologies. You will apply statistical methods for the combined analysis of the obtained data with the aim to retrieve information about both local coordination and chemical composition in these materials at the nanoscale.

We are looking for a highly motivated PhD student (f/m/d) in the field of materials science who is passionate about both physical chemistry and nanoscale characterization of materials.

YOUR TASKS: The PhD position is part of the E-MOSAIC project, which is focused on the development of electron microscopy approaches for the characterization of complex hybrid materials at the atomic scale. As a member of the project team, you will contribute to establishing and applying low-electron-dose workflows for the analysis of the local structure in soft functional materials (semi-crystalline and amorphous materials) using electron diffraction and electron energy loss spectroscopy methodologies. You will apply statistical methods for the combined analysis of the obtained data with the aim to retrieve information about both local coordination and chemical composition in these materials at the nanoscale. YOUR PROFILE:

• You have a Master’s degree in Chemistry/Materials Science/Physics or a closely related field, with a strong interest in transmission electron microscopy and/or spectroscopy techniques.
• Experience with material characterization using microscopy and/or spectroscopy techniques is an advantage.
• Ability to work as a member of an international, multi-disciplinary team.
• Excellent communication and writing skills, thorough command of the English language. German language knowledge is very beneficial. WE OFFER: We offer excellent conditions for you to complete your doctoral degree:
• An exciting position in a dynamic research team located on the attractive research campus Saarbruecken.
• An opportunity to work with high-end microscopy equipment, including an aberration corrected transmission electron microscope, and different scanning electron microscopes.
• Strong support to perform high-quality research and to publish and present your research results (journals, national and international conferences).
• A comprehensive benefits package (flexible working hours, mobile working, company pension scheme).  Desired starting date: as soon as possible, salary level E13 TV-L 60%, contract limited to three years (with possible extension). We are looking forward to receiving your application (CV, a complete list of publications, one-page motivation letter, at least two letters of reference) by November 15th, 2025. Please use our online application system. The INM practices an open and appreciative corporate culture in which the existing diversity is promoted and lived. The institute is an equal-opportunity employer with a certified family-friendly policy, and it provides offers for a better work life balance, flextime and mobile working. We promote the professional opportunities of women and strongly encourage them to apply. Severely disabled applicants with equal qualifications and aptitude will be given preferential consideration.

Science is too slow. The discoveries that could cure disease are bottlenecked by manual work. What if we could change that?

At Cytely, we’re not just making discovery faster. We’re building a world where science accelerates itself to unlock human biology and cure all preventable disease.

We are seeking a scientifically trained specialist who can identify research needs, initiate meaningful conversations, and guide prospects from first contact through onboarding. You will work directly with researchers to uncover how microscopy and image analysis can accelerate their work, demonstrate how Cytely can provide value, and ensure a smooth handoff into the platform. This role combines scientific credibility with relationship-building and will involve close collaboration with our applications and product teams.

Key Responsibilities

• Prospect and qualify potential customers, identifying research pain points.
• Lead early-stage discussions to align Cytely’s platform with customer needs.
• Design tailored onboarding experiences, ensuring new users adopt successfully.
• Represent Cytely at meetings, conferences, and presentations.
• Contribute to customer-facing content such as case studies, campaigns, and educational material.

Qualifications

• Advanced degree (PhD or MSc) in biomedical sciences or related field.
• Hands-on experience with microscopy hardware and software.
• Strong understanding of image analysis and segmentation workflows.
• Proven ability to communicate complex scientific ideas to diverse audiences.
• Comfortable in customer-facing settings, with willingness to travel.

We are looking for a scientist with strong microscopy and image analysis expertise to ensure our existing customers thrive on Cytely’s platform. You will support users after onboarding, helping them gain maximum value, designing additional analysis pipelines where needed, and ensuring long-term satisfaction and renewal. While the role is primarily focused on customer success, it will also include light prospecting and lead qualification.

Key Responsibilities

• Support customers after onboarding, ensuring smooth adoption and satisfaction.
• Develop and refine analysis workflows tailored to ongoing customer projects.
• Act as a trusted advisor to maintain strong relationships and drive renewals.
• Identify upsell opportunities and collaborate with the sales team.
• Occasionally qualify new leads and support early-stage discussions.

Qualifications

• Advanced degree (PhD or MSc) in biomedical sciences or related field.
• Hands-on experience with microscopy workflows and image analysis tools.
• Strong communication and problem-solving skills.
• Experience in customer-facing roles, with the ability to build long-term relationships.
• Flexible mindset to contribute to both post-sales and occasional pre-sales activities.

The Center for Microscopy and Image Analysis (ZMB) is a nationally and internationally recognized Core Facility at the University of Zurich (UZH), providing access to state-of-the-art light and electron microscopy. With a team of over 15 highly qualified staff members, the ZMB supports and collaborates with more than 200 research groups across the University, offering advanced expertise, customized support, and training in cutting-edge imaging technologies. As one of Europe's leading research universities with an international reputation for excellence, UZH provides an outstanding environment for scientific innovation, interdisciplinary exchange, and collaboration

Your responsibilities

The Head of the ZMB will play a key role in shaping the future of microscopic imaging at UZH. She or he will be responsible for leading and continuously advancing all activities of the Core Facility within the framework set by the ZMB Steering Committee, which consists of user representatives.

Key duties and responsibilities:

• Drive the development and enhancement of the facility's services, methodologies, protocols, and instrumentation portfolio - including integration of emerging technologies and prototype developments into sustainable, high-performance user services
• Advance image analysis by designing and implementing innovative IT and data management strategies in collaboration with the UZH BioVisionCenter
• Active engagement in national and international microscopy networks and initiatives
• Lead and support staff at all levels, including recruitment, performance planning, and structured career development
• Design and promote training programs for facility users and strengthen the user community network
• Develop and maintain strong scientific and commercial collaborations
• Shape long-term strategies for the facility in close cooperation with the Steering Committee
• Oversee administrative and financial operations and report regularly to the Steering Committee

  Your profile

  We are seeking a dynamic and innovative leader person with:

• An academic education (PhD or equivalent) in the life-sciences or a related discipline
• An exceptional expertise in advanced microscopic techniques (light- and electron- microscopy)
• A strong record of scientific and/or technological achievements
• Proven leadership and facility management skills, including the ability to lead a diverse team and to foster collaborations across disciplines
• A clear service orientation, with the commitment to providing high-quality support to a broad user community
• A vision for the future development of microscopy and image analysis in life sciences and beyond

UZH is an equal opportunity employer and explicitly encourages applications from qualified women.

Information on your application

Please submit your application (motivation letter, curriculum vitae, certificates) in a single PDF file until December 15, 2025.

This role offers a unique opportunity to apply and integrate advanced image processing techniques to progress the fields of biomedical and life sciences. Working within a team of biologists, physicists and engineers, the specialist will help build robust and reproducible protocols to extract meaningful quantitative information from both simple and complex microscopy datasets and present it effectively. 

This is a joint position between Biomedicum Imaging Unit BIU at the Meilahti campus and Light Microscopy Unit LMU at the Viikki campus, which are open access core facilities offering a wide variety of basic and advanced light microscopy techniques to several hundred local, national and international users annually.

The position This role offers a unique opportunity to apply and integrate advanced image processing techniques to progress the fields of biomedical and life sciences. Working within a team of biologists, physicists and engineers, the specialist will help build robust and reproducible protocols to extract meaningful quantitative information from both simple and complex microscopy datasets and present it effectively. 

This is a joint position between Biomedicum Imaging Unit (BIU) at the Meilahti campus and Light Microscopy Unit (LMU) at the Viikki campus, which are open access core facilities offering a wide variety of basic and advanced light microscopy techniques to several hundred local, national and international users annually.    Specific tasks •  Develop and apply different image analysis approaches to, for example, segment, track, and characterize cellular structures and dynamics in biological systems, including 3D and timelapse light microscopy data, and embed these approaches into the general service portfolio of BIU/LMU. •  Maintain custom scripts and software tools for microscopy image analysis and data processing, implement image analysis according to FAIR principles. •  Create a well organised, version controlled (including software version packaging) space for sharing image analysis workflows. •  Communicate concepts of image analysis and their relevance for biological questions to experts and non-experts. •  Take part in the planning stage of users’ imaging projects. •  Organise monthly Helsinki Bioimaging Call4Help sessions for users.

In this project, you will contribute to both engineering and neurobiology. First, you will help build a light-sheet microscope optimized for voltage imaging at the single-cell and subcellular level in live larval zebrafish (reference↗). The development of this system will be supported by experienced colleagues and the Biology Image Center↗ team. Once the microscope is established, you will use it to investigate the electrophysiological properties of cerebellar Purkinje cells with advanced voltage indicators such as Voltron2. The ultimate goal is to uncover how Purkinje cells alter their dendritic signaling and spiking characteristics under different sensory or chemogenetic conditioning paradigms, and to determine how these changes may be mediated through intrinsic plasticity or brain state.

Position Highlights:

• The Research Specialist III should possess knowledge that will allow them to exercise independent judgment in developing methods, techniques and evaluation criteria for obtaining research results.
• Act independently to determine methods and procedures on new assignments and may provide guidance and oversee the activities of lower-level staff.
• Provide training and assistance on various microscopy techniques including but not limited to: Fluorescence, Intravital, Live Cell, Confocal, 2-photon, Digital Pathology, and Image Analysis. 
• Work with other staff members of the core to complete projects and perform core equipment maintenance.
• Attend in-house courses, seminars and workshops, related to core activities and cancer biology.
• Assist customers with grant proposals and manuscript preparation.
• Participate in national Shared Resources and Microscopy organizations. The Ideal Candidate:
• Experienced biotechnology research professional.
• The successful candidate will communicate effectively with the research community and provide superior customer service to the core's clients.
• Must demonstrate the ability to assist and train clients in instrument operation and independently perform regular laboratory maintenance and QC.
• Capable of autonomously performing all tasks required by the core for extended periods.
• The candidate will have a broad knowledge of advanced microscopy technologies and image analysis.
• Master’s degree in Core related field of study is preferred.
• Experience with advanced microscopy applications, especially confocal, 2-photon, and/or light-sheet.
• Or experience with Digital Pathology and Spatial Biology applications. Responsibilities:
• Work on-site during normal operating hours of the core. 
• Occasional work outside normal operating hours to complete time-sensitive experiments.
• Train and assist customers on a variety of microscope systems.
• Train and assist customers with Image Analysis on multiple software platforms.
• Develop methods and standard procedures to facilitate client's research projects.
• Maintain and troubleshoot equipment and customer projects
• Assist core manager with administrative tasks.
• Work closely with other research cores to advance customer projects.
• Communicate effectively with customers including presentation of data to faculty members.
• Participate in Microscopy courses, seminars, and workshops.
• Maintain a safe working environment and follow universal safety precautions. Credentials and Qualifications:
• BA/BS in Core related field of study is required, with core specific advanced training and work experience. Requires at least 5 years in science related work and/or post-graduate coursework. Requires at least 3 years in core facility specific applications and at least 2 years of that in research-based technology.
• Work experience in multi-user core facility preferred..

Join Our Team! St. Jude Children’s Research Hospital is seeking a highly motivated Image Analyst and Microscopist to join our cutting-edge Microscopy Core Facility in the Department of Cell and Molecular Biology. This is a full-time position available at either the Lead Researcher or Associate Scientist level, depending on experience. The role will focus on helping users with advanced image analysis and protocol development for high-content microscopy, super-resolution microscopy, and tissue imaging. This is an outstanding opportunity to apply your expertise in advanced imaging, high-content microscopy, and computational analysis to support groundbreaking biomedical research. You will join a close-knit team of specialists including an imaging expert, a data analyst/Python programmer, and the core director—working together to deliver innovative solutions for St. Jude scientists.

What You’ll Do

• Provide expert support for users, developing advanced imaging and analysis workflows across platforms such as high-content microscopy, super-resolution imaging, and tissue imaging.
• Design and implement rigorous, reproducible image analysis pipelines using open-source tools (Fiji, napari, ilastik, CellProfiler, custom Python notebooks) and commercial solutions (Imaris, Huygens Professional, LAS X, NIS Elements, Zen Blue/Black, MATLAB).
• Partner with the core director and imaging team to ensure high-quality user assistance and project documentation.
• Write user guides, protocols, and workflow documentation to enhance training and reproducibility across projects.
• Collaborate with Research Information Services to leverage CPU and GPU cluster computing resources for large-scale image analysis.
• Train and mentor users on a variety of microscopy modalities, including confocal, STED, SIM, FLIM, TIRF, STORM, HCA, and holotomography.

Other responsibilities: 

• Participate in the teaching and training of staff and students on image analysis techniques through workshops and 1-to-1 training.
• Stay at the forefront of microscopy and analysis by developing new protocols and workflows ahead of emerging needs.
• Interact regularly with vendors, technical specialists, and service engineers to maintain robust instrumentation.

What You Can Expect

• Joining a small and dynamic team composed of individuals with complementary skills in the field of microscopy and image analysis.
• An exciting role within a rapidly expanding core facility (from 3,500 user hours in 2022 to over 8,000 in 2024).
• Integration into the new Department of Imaging Sciences and a network of core facilities across campus.
• Opportunities to broaden your skills by collaborating with researchers across diverse scientific areas of St. Jude.

Minimum Education

• Bachelor's degree in relevant scientific area is required

Minimum Experience Associate Scientist Level:

• 7 + years of research experience is required
• 5 + years of research experience is required with a Master’s degree
• 2 + years of research experience is required with a PHD
• Experience leading and supporting research experiments preferred
• Some experience leading lab and scientific project coordination, maintenance, and other research support activities preferred
•  Experience in light microscopy (from theoretical knowledge of super-resolution modalities to experiment design) preferred.
• Demonstrated experience in data analysis of large and/or complex datasets Lead Researcher Level:
• 5+ years of research experience is required
• 3+ years of experience is required with a Master’s degree
• No prior experience required with a PHD
• Strong knowledge and experience in understanding and application of underlying principles related to techniques being performed
• Experience in light microscopy (from theoretical knowledge of super-resolution modalities to experiment design) preferred.

Compensation

In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65,520 - $114,400 per year for the role of Lead Researcher/Associate Scientist- Image Analyst and Microscopist.Explore our exceptional benefits! St. Jude is an Equal Opportunity Employer

No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

PROGRAM DESCRIPTION At Frederick National Laboratory, the Cancer Research Technology Program (CRTP) is a multi-disciplinary hub where emerging technologies, biological expertise and research capabilities are developed and implemented in collaboration with intramural National Cancer Institute investigators and other researchers. Within the CRTP is the Center for Volume Electron Microscopy (CvEM); in our group, scientists work in a highly collaborative environment to develop and deploy cutting-edge technologies for high-resolution 3-D volume EM and correlative microscopy (CLEM) of cells and tissues with research and/or clinical relevance. Our group works on innovations in sample preparation, imaging strategies and data processing/analysis, with an emphasis on artificial intelligence (AI) aided image segmentation and visualization.

KEY ROLES/RESPONSIBILITIES

• Operation of scanning and transmission electron microscopes, including biological sample preparation

• Simple data analysis and visualization using computational tools

• Rigorous record keeping

• BASIC QUALIFICATIONS To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:

• Possession of Bachelor’s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) or four (4) years relevant experience in lieu of degree. Foreign degrees must be evaluated for U.S. equivalency

• In addition to the education requirement, a minimum of two (2) years of related experience is required

• Prior experience with conventional biological electron microscopy (imaging, sample prep, data analysis, and record keeping)

• Experience with 2D and 3D visualization software

• Ability to obtain and maintain a security clearance

• PREFERRED QUALIFICATIONS  Candidates with these desired skills will be given preferential consideration:

• Publications in volume electron microscopy

• Experience with correlative microscopy (CLEM)

• Ease with computation (running scripts, knowledge of data/metadata concepts)

• JOB HAZARDS

• This position is subject to working with radioactive material and requires

• to become an approved radiation worker

The Team CZI and its Biohub Network supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease. 

Achieving our mission will only be possible if scientists are able to better understand human biology. To that end, we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems — paving the way for new discoveries that will change medicine in the decades that follow:

• Building an AI-based virtual cell model to predict and understand cellular behavior
• Developing novel imaging technologies to map, measure and model complex biological systems  
• Creating new tools for sensing and directly measuring inflammation within tissues in real time.tissues to better understand inflammation, a key driver of many diseases
• Harnessing the immune system for early detection, prevention, and treatment of disease

Our work in science is focused on doing fundamental research to better understand human biology and building the tools and technology that move science forward to prevent disease and get to cures faster. Join us in accelerating science.

The Opportunity 

At CZI, we are generating unprecedented scientific datasets that drive biological modeling innovation:

• Billions of standardized cells of single-cell transcriptomic data, with a focus on measuring genetic and environmental perturbations
• 10s of thousands of donor-matched DNA & RNA samples
• PB-scale static and dynamic imaging datasets
• TB-scale mass spectrometry datasets
• Diverse, large multi-modal biological datasets that enable biological bridges across measurement types and facilitate multi-modal model training to define how cells act.

After model training, we make all data products available through public resources like CELLxGENE Discover and the CryoET Portal, used by tens of thousands of scientists monthly to advance understanding of genetic variants, disease risk, drug toxicities, and therapeutic discovery.

As a Senior Staff Data Scientist, you'll lead the creation of groundbreaking imaging datasets that decode cellular function at the molecular level, describe development, and predict responses to genetic or environmental changes. Working at the intersection of data science, biology, and AI, you'll define data needs, format standards, analysis approaches, quality metrics, and our technical strategy, creating systems to ingest, transform, and validate and deploy data products. 

Success for this role means delivering high-quality, usable datasets that directly address modeling challenges and accelerate scientific progress. Join us in building the data foundation that will transform our understanding of human biology and move us along the path to curing, preventing, and managing all disease.

What You’ll Do

• Define the technical strategy for a robust imaging data ecosystem and build data ingestion pipelines, define data formats, write validation tools, QC metrics, and analysis pipelines.
• Collaborate with ML engineers, AI Researchers, and Data Engineers to iteratively evaluate, refine and grow datasets to maximize model performance. 
• Discover and define new data generation opportunities, and manage the delivery of those data products to our AI team.
• Collaborate with engineers, product managers, UX designers, and other data scientists to publish valuable datasets as part of CZI's open data ecosystem.

What You’ll Bring

• 10+ years of experience with large scale biological imaging data.
• Demonstrated delivery of multiple large biological data products.
• Experience with big data: extraction, transport, loading, databases, standardization, validation, QC, and analysis.
• Experience with processing and orchestration pipelines, such as Argo Workflows, Databricks
• Strong fundamentals in statistical reasoning and machine learning.
• Experience with biological data analysis and QC best practices
• Excellent written and verbal communication skills.
• Enthusiasm to ramp up on technologies and learn new domains.
• Experience working in a multidisciplinary environment (engineering, product, AI Research).

Senior Postdoctoral Position in Single Molecule Microscopy Department of Molecular Immunology at the University of Freiburg (Germany) (https://lillemeier.biologie.uni-freiburg.de)   We are seeking a highly creative, collaborative, and motivated Senior Postdoctoral Researcher with significant experience in single molecule microscopy who is interested in visualizing immune responses in T cells.   This full-time senior postdoctoral position is available from 1st of January 2026 with the possibility of becoming permanent after 2 years. The salary is at E13 level by the TV-L agreement (Tarifvertrag für den öffentlichen Dienst der Länder / collective agreement for public employers). We welcome applicants from different areas, e.g. immunology, biology, physics and engineering, with considerable expertise in fluorescence single molecule microscopy using state-of-the-art equipment and a keen interest in immunology. The candidate is expected to conduct studies independently and supervise postdoctoral researchers and students on microscopy projects. This position requires a Ph.D. degree (or equivalent), and publications in peer-reviewed journals. We are an equal opportunity employer and encourage applications from candidates of all genders.  

The position is designed to study spatio-temporal mechanisms that control the assembly and signal transduction of the TCR and PD1 pathways at the T cell plasma membrane.   Our group is interested in the regulation of lymphocyte activity and functions during cancer and autoimmunity. Current research is focused on the activating T cell receptor (TCR) and inhibitory PD1 pathways in T cells. We apply multidisciplinary approaches that combine cutting-edge fluorescence microscopy with biophysics, biochemistry and molecular biology to elucidate how protein conformations, modifications and assembly at the plasma membrane control signal transduction. Specifically, we have discovered that the T cell signaling pathways are segregated into distinct plasma membrane nanodomains that concatenate upon T cell stimulation. We are studying how the signaling pathways utilize nanodomain distributions and dynamics, and how signals are exchanged between them. We aim to identify and modulate spatio-temporal mechanisms that are specific to signaling proteins and/or pathways. Our goal is to determine the potential of these mechanisms as future drug targets for immunotherapies.   To Apply: Please submit (1) a letter of motivation including a description of past research accomplishments and future research interests/goals (not more than two pages), (2) curriculum vitae (CV) with publication list and (3) at least three contact details for referees. Please, send your application in a single pdf file to: lillemeier@bio.uni-freiburg.de

Postdoctoral Fellow - Biomolecular Condensates, Protein Dynamics & GI Disease Weill Cornell Medicine - Division of Gastroenterology and Hepatology

The Platt Lab in the Division of Gastroenterology and Hepatology at Weill Cornell Medicine invites applications for a postdoctoral research position in molecular and cellular biology. We investigate how changes in protein mobility and biomolecular condensates contribute to human disease, with a particular focus on gastrointestinal pathophysiology.

The successful candidate will lead projects using advanced imaging techniques, including fluorescence recovery after photobleaching (FRAP) and single-particle tracking (SPT), to uncover how environmental stressors disrupt biomolecular condensates and protein dynamics. Our goal is to reveal disease mechanisms and identify tractable therapeutic targets. We are a newly established and growing lab that values scientific rigor, creativity, and collaboration.

Responsibilities

• Design and execute independent experiments using advanced imaging and molecular biology techniques
• Analyze protein mobility using quantitative imaging and computational tools
• Contribute to manuscript and grant writing
• Present research findings at internal seminars and external conferences
• Collaborate across disciplines to explore emerging models of disease pathogenesis

Qualifications

• PhD, MD/PhD, or equivalent degree in molecular biology, biophysics, systems biology, or a related field
• Strong background in imaging, microscopy, and cell biology
• Experience with image analysis software (e.g., ImageJ/FIJI, MATLAB, Python)
• Interest or experience in biomolecular condensates, protein dynamics, and/or redox biology
• Demonstrated ability to publish high-quality scientific work
• Creative, collaborative, and motivated to uncover fundamental disease mechanisms

Application Instructions To apply, please send the following to Dr. Jesse Platt at jep4025@med.cornell.edu:

• A one-page cover letter describing your research background and interests
• CV with a list of publications
• Contact information for 2–3 references The position is available immediately and will remain open until filled. Salary range: $61,008 – $74,088, based on experience and in accordance with WCM’s minimum stipend policy. Weill Cornell Medicine is an equal opportunity employer and encourages applications from candidates of diverse backgrounds. Learn more about our work: https://www.linkedin.com/in/jesse-platt-md-phd-a3a42621/

The Neuron Signaling Lab at NUS is seeking a motivated and skilled Research Fellow to join our interdisciplinary neuroscience team. We use advanced optical imaging and behavioral analysis to uncover how molecular pathways shape brain function, aiming to bridge molecular and systems neuroscience.

Our core platforms include: § 3D & 4D confocal fluorescence microscopy § 1P & 2P fluorescence microendoscopy § Fiber photometry & optogenetics § Genetically encoded molecular tools We focus on behaviors such as reward learning, fear learning and motor learning, with strong interest in primary cilia and nuclear signaling in the brain.

Position Summary: We seek a candidate with strong expertise in microscopy and computational image analysis to: 1. Support and enhance ongoing imaging projects in the lab 2. Develop AI-powered pipelines for analysis of microendoscopic calcium imaging, confocal fluorescence microscopy, and behavioral videos 3. Lead cross-modality image registration applications 4. Launch new projects that leverage our optical expertise to probe brain function

Preferred Qualifications & Expertise: § PhD in neuroscience, bioengineering, computational biology, or related field § At least one strong first-author publication in microscopy and/or image analysis is required § Strong background in optical imaging principles and microscopy (e.g., confocal, 2P, STED, or light sheet) § Demonstrated experience in image processing, quantitative analysis, and biological interpretation § Proficiency in AI/machine learning tools for image segmentation, transformation, registration, or tracking § Solid mathematical foundation for image analysis (e.g., affine transformations, convolutional filters, matrix and morphological operations) § Programming skills in Python, MATLAB, and/or experience with ImageJ, Napari, Imaris, TensorFlow, or PyTorch § Familiarity with in vivo imaging, optogenetics or spatial transcriptomics methods is a plus § Strong interest in bridging biological questions with quantitative approaches § Excellent problem-solving, collaborative, and communication skills

Environment & Opportunities: Our lab is part of a highly multidisciplinary research environment, with close collaborations in biochemistry, neural computation, and genomics. The successful candidate will be embedded in a vibrant scientific community and have access to a full suite of optical and behavioral neuroscience platforms. In addition to technical capability, we are looking for an individual excited by our novel multi-scale approach to neurobiology and eager to tackle complex, integrative questions.

Yale School of Medicine https://medicine.yale.edu/fib-sem/ The FIB-SEM Collaboration Core (F-SCC) at Yale School of Medicine is seeking a Senior Staff Scientist to join our pioneering team at the forefront of volume electron microscopy. The F-SCC leverages cutting-edge enhanced Focused Ion Beam Scanning Electron Microscopy (eFIB-SEM) technology to achieve large-volume imaging at nanometer isotropic resolution.

Position Summary: Under the supervision of the F-SCC Director, the Senior Staff Scientist will manage the image acquisition pipeline. Responsibilities include:

• Performing X-ray-guided FIB-SEM sample preparation
• Conducting enhanced FIB-SEM image acquisition
• Carrying out image registration, alignment, segmentation, and data analysis The successful candidate will be expected to work independently, multitask effectively, and perform experiments using advanced laboratory techniques, including enhanced FIB-SEM and X-ray micro-computed tomography (micro-CT). Collaboration and close communication with the supervisor, collaborators, and core members are essential.

Qualifications:

• Strong expertise in electron microscopy and related imaging technologies preferred
• Ability to manage multiple projects simultaneously and work independently
• Excellent teamwork, communication, and organizational skills

Consideration: please submit an application and cover letter describing how your previous research accomplishments and scientific interests fit with the scope of the research via this link.

The successful candidate will be an integral part of a team whose aim is to discover the next generation genetic therapies for a wide range of indications. The position requires enthusiasm, passion, attention to detail, and a desire to create new medicines for patients.